1062 10 20655 http://socictopen.socict.org/files/original/3afb177f9f2380a2127d39f8b26bdd57.pdf 6c05511be1024860f0cdc92443d27d65 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Complex Social Networks are Missing in the Dominant COVID-19 Epidemic Models Creator An entity primarily responsible for making the resource Gianluca Manzo Description An account of the resource In the COVID-19 crisis, compartmental models have been largely used to predict the macroscopic dynamics of infections and deaths and to assess different non-pharmaceutical interventions aimed to contain the microscopic dynamics of person-to-person contagions. Evidence shows that the predictions of these models are affected by high levels of uncertainty. However, the link between predictions and interventions is rarely questioned and a critical scrutiny of the dependency of interventions on model assumptions is missing in public debate. In this article, I have examined the building blocks of compartmental epidemic models so influential in the current crisis. A close look suggests that these models can only lead to one type of intervention, i.e., interventions that indifferently concern large subsets of the population or even the overall population. This is because they look at virus diffusion without modelling the topology of social interactions. Therefore, they cannot assess any targeted interventions that could surgically isolate specific individuals and/or cutting particular person-to-person transmission paths. If complex social networks are seriously considered, more sophisticated interventions can be explored that apply to specific categories or set of individuals with expected collective benefits. In the last section of the article, I sketch a research agenda to promote a new generation of network-driven epidemic models. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Compartmental models, small-world networks, Scale-free Networks, egocentered networks, agent-based computational models Identifier An unambiguous reference to the resource within a given context 10.6092/issn.1971-8853/10839 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Sociology (General), Social Sciences http://socictopen.socict.org/files/original/fe4315ff45d5b6248e754d3c69b58a2c.pdf 481b7af21fad454e2051c2b5bcade263 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Challenge of the Energy Sector of Russia during the 2020 COVID-19 Pandemic through the Example of the Republic of Tatarstan: Discussion on the Change of Open Innovation in the Energy Sector Creator An entity primarily responsible for making the resource Anastasia Kulachinskaya, Irina G. Akhmetova, Varvara Y. Kulkova, Svetlana B. Ilyashenko Description An account of the resource Today the world economy is handling an economic crisis caused by the pandemic of a new coronavirus infection (COVID-19), announced by the WHO, as well as by fluctuations in the international energy market and by the development of “green energy”. The crisis, named the “2020 crisis”, is notable for the divergence of the sectoral dynamics of development, with a declining development trend in some industries and the rapid growth of others. The crisis is etymologically relevant to the energy sector, a sector which is important for the survival and specialization of the Russian Federation. This research is aimed at describing the status and highlighting the socioeconomic effects, constraints (economic and social risks), and “growth points” of the energy sector in the modern realities of the 2020 crisis. Methods. The method of in-depth interview was used. The need for studying expert opinion is based on the fundamental principles of implementation research, according to which the success of state sectoral policy depends on its perception and support by stakeholders. Top managers of energy enterprises acted as the experts (N = 10). The interviews were conducted in April 2020. The method of incremental approximation and coding (open and axial) were used for a high-quality discourse analysis. Results. The conducted study revealed divergence of sectoral dynamics of energy consumption, which is a translation of the immanent features of the 2020 crisis into the energy sector. The detected constraints are reserved development prerequisites of “green energy” and reduced investments in development programs. The potential “growth points” include intensified digitalization of the energy sector and the need for institutional changes in taxation in the energy sector, recognized by experts. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource energy economy, state policy during the “2020 crisis”, anti-crisis actions of companies Identifier An unambiguous reference to the resource within a given context 10.3390/joitmc6030060 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Business, Management. Industrial management http://socictopen.socict.org/files/original/c3a3df78372ba4c1e7ffd89d7364f100.pdf 3c82fe9c9c88150cb3356cafb7972e3a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource (Opportunities) Death of Newspaper Industry in Digital Age and Covid-19 Pandemic Creator An entity primarily responsible for making the resource Supadiyanto Supadiyanto Description An account of the resource Newspaper industry is entering a state of emergency in Indonesia. Dewan Pers demands that the government provide incentives to press companies during Covid-19. The growth in the number of internet users, the downward trend in advertising revenue, and the number of newspaper circulation are problems in the print media business. List of questions in this study: what are the trends in the use of internet technology and social media in Indonesia?; why did various newspaper companies in Indonesia collapse and die in the digital era?; how is the effort to save the newspaper business? Meanwhile, the research paradigm is qualitative. The time of the study is November 2019 to May 2020. The results of this research, the growth in the number of internet users has been extraordinary in the last 20 years. Signs of the newspaper era are over, strengthened by many newspaper companies turning to online media. The number of readers fell, the number of advertisers plummeted, number of copies narrowed, and the cost of producing newspapers became increasingly expensive to cause the closure of various newspaper companies. Rescue by attracting young readers and doing various innovations. Tragically, the print media industry will end and die on its own. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19 pandemic, Opportunities, Digital Age, collapse, newspaper industry Identifier An unambiguous reference to the resource within a given context 10.26623/themessenger.v12i2.2244 Source A related resource from which the described resource is derived Jurnal the Messenger Publisher An entity responsible for making the resource available Universitas Semarang Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Communication. Mass media http://socictopen.socict.org/files/original/c309f969c41ee3bba6c210ffb2099fdf.pdf c1dac5a31752fc28495dda3fdac53059 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 Infection in Cancer Patients: A Picture of an Italian Onco-Covid Unit Creator An entity primarily responsible for making the resource Umberto Malapelle, Maria Lucia Reale, Paolo Bironzo, Valentina Bertaglia, Erica Palesandro, Gianmarco Leone, Fabrizio Tabbò, Maristella Bungaro, Marco Audisio, Annapaola Mariniello, Simonetta G. Rapetti, Rosario F. Di Stefano, Elisa Artusio, Enrica Capelletto, Paola Sperone, Adriana Boccuzzi, Marco Calandri, Alberto Perboni, Francesco Passiglia, Silvia Novello Description An account of the resource Background: The world, and Italy on the front lines, has experienced a major medical emergency due to the novel coronavirus outbreak. Cancer patients are one of the potentially most vulnerable cohorts of people, but data about their management are still few.Patients and Methods: In this monocentric retrospective study we included all SARS-CoV-2 oncological patients accepted, between March 27th and April 19th 2020, at the Onco-COVID Unit at San Luigi Gonzaga Hospital, one of the few Italian oncological-COVID wards. Data were obtained from medical records.Results: Eighteen cancer patients with COVID-19 were included. The mean (±SD) age of patients was 67 ± 14 years, 89% were men. Seven (39%) developed infection in communities and 11 (61%) during hospitalization. Lung cancer was the most frequent type of cancer (10, 56%). Seven patients (39%) were symptomatic for COVID-19 at the time of diagnosis and symptoms began 2 (±2) days before. The most common were shortness of breath and diarrhea. Fever was present in 5 patients (28%). Among the 11 asymptomatic patients, 8 (73%) became symptomatic during the hospitalization (mean time of symptoms onset 4 days ±4). Six patients (33%) were on active anti-tumor treatment: 2 (33%) received anti-tumor therapy within 2 weeks before the infection diagnosis and 2 (33%) continued oncological treatment after SARS-CoV-2 positivity. Eight (44%) patients died within a mean of 12 days (±8) from the infection diagnosis.Conclusions: Our series confirms the high mortality among cancer patients with COVID-19. The presence of asymptomatic cases evidences that typical symptoms and fever are not the only parameters to suspect the infection. The Onco-Covid unit suggests the importance of a tailored and holistic approach, even in this difficult situation. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Lung cancer, Cancer patients, Asymptomatic patients, Italian retrospective study Identifier An unambiguous reference to the resource within a given context 10.3389/fonc.2020.01722 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neoplasms. Tumors. Oncology. Including cancer and carcinogens http://socictopen.socict.org/files/original/182aeb9e5991df132501200404483cee.pdf 11ebe0a4cc06f8dfddef1225a47e31df Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Chronic Neurology in COVID-19 Era: Clinical Considerations and Recommendations From the REPROGRAM Consortium Creator An entity primarily responsible for making the resource Vijay Kumar Chattu, Sonu Bhaskar, Sonu Bhaskar, Sonu Bhaskar, Sian Bradley, Sian Bradley, Simon Israeli-Korn, Simon Israeli-Korn, Bindu Menon, Bindu Menon, Vijay Kumar Chattu, Pravin Thomas, Pravin Thomas, Jasvinder Chawla, Jasvinder Chawla, Rajeev Kumar, Rajeev Kumar, Paolo Prandi, Paolo Prandi, Daniel Ray, Daniel Ray, Sailaja Golla, Sailaja Golla, Nirmal Surya, Nirmal Surya, Harvey Yang, Harvey Yang, Sandra Martinez, Sandra Martinez, Mihriban Heval Ozgen, Mihriban Heval Ozgen, Mihriban Heval Ozgen, John Codrington, John Codrington, Eva María Jiménez González, Eva María Jiménez González, Mandana Toosi, Mandana Toosi, Nithya Hariya Mohan, Nithya Hariya Mohan, Koravangattu Valsraj Menon, Koravangattu Valsraj Menon, Abderrahmane Chahidi, Abderrahmane Chahidi, Abderrahmane Chahidi, Abderrahmane Chahidi, Susana Mederer Hengstl, Susana Mederer Hengstl Description An account of the resource With the rapid pace and scale of the emerging coronavirus 2019 (COVID-19) pandemic, a growing body of evidence has shown a strong association of COVID-19 with pre- and post- neurological complications. This has necessitated the need to incorporate targeted neurological care for this subgroup of patients which warrants further reorganization of services, healthcare workforce, and ongoing management of chronic neurological cases. The social distancing and the shutdown imposed by several nations in the midst of COVID-19 have severely impacted the ongoing care, access and support of patients with chronic neurological conditions such as Multiple Sclerosis, Epilepsy, Neuromuscular Disorders, Migraine, Dementia, and Parkinson disease. There is a pressing need for governing bodies including national and international professional associations, health ministries and health institutions to harmonize policies, guidelines, and recommendations relating to the management of chronic neurological conditions. These harmonized guidelines should ensure patient continuity across the spectrum of hospital and community care including the well-being, safety, and mental health of the patients, their care partners and the health professionals involved. This article provides an in-depth analysis of the impact of COVID-19 on chronic neurological conditions and specific recommendations to minimize the potential harm to those at high risk. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource guidelines, coronavirus disease 2019 (covid-19), Protocols, healthcare services, neurodegenerative disorders, chronic neurological disease Identifier An unambiguous reference to the resource within a given context 10.3389/fneur.2020.00664 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neurology. Diseases of the nervous system http://socictopen.socict.org/files/original/a5e10b9f0277bdf42da859150e991b59.pdf da2579fe6637c514f2433d7377170b26 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Molecular Evolution and Structural Mapping of N-Terminal Domain in Spike Gene of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Creator An entity primarily responsible for making the resource Asif Naeem, Maaweya E. Hamed, Majed F. Alghoribi, Waleed Aljabr, Hadel Alsaran, Mushira A. Enani, Bandar Alosaimi Description An account of the resource The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a lethal zoonotic pathogen circulating in the Arabian Peninsula since 2012. There is no vaccine for MERS and anti-viral treatment is generally not applicable. We investigated the evolution of the MERS-CoV spike gene sequences and changes in viral loads over time from patients in Saudi Arabia from 2105–2017. All the MERS-CoV strains belonged to lineage 5, and showed high sequence homology (99.9%) to 2017 strains. Recombination analysis showed a potential recombination event in study strains from patients in Saudi Arabia. The spike gene showed eight amino acid substitutions, especially between the A1 and B5 lineage, and contained positively selected codon 1020. We also determined that the viral loads were significantly (p < 0.001) higher in fatal cases, and virus shedding was prolonged in some fatal cases beyond 21 days. The viral concentration peaked during the first week of illness, and the lower respiratory specimens had higher levels of MERS-CoV RNA. The presence of the diversifying selection and the topologies with the structural mapping of residues under purifying selection suggested that codon 1020 might have a role in the evolution of spike gene during the divergence of different lineages. This study will im­prove our understanding of the evolution of MERS-CoV, and also highlights the need for enhanced surveillance in humans and dromedaries. The presence of amino acid changes at the N-terminal domain and structural mapping of residues under positive selection at heptad repeat 1 provides better insight into the adaptive evolution of the spike gene and might have a potential role in virus-host tropism and pathogenesis. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Middle East respiratory syndrome coronavirus, evolution, viral load, Spike gene Identifier An unambiguous reference to the resource within a given context 10.3390/v12050502 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology http://socictopen.socict.org/files/original/d4b55b7230a44bbfb54bb73d142a6d1e.pdf 7b5d116ce076a706646c1e8cd44da69a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Growth Rate and Acceleration Analysis of the COVID-19 Pandemic Reveals the Effect of Public Health Measures in Real Time Creator An entity primarily responsible for making the resource Marco Milanesi, Yuri Tani Utsunomiya, Yuri Tani Utsunomiya, Adam Taiti Harth Utsunomiya, Rafaela Beatriz Pintor Torrecilha, Silvana de Cássia Paulan, José Fernando Garcia, José Fernando Garcia, José Fernando Garcia Description An account of the resource Background: Ending the COVID-19 pandemic is arguably one of the most prominent challenges in recent human history. Following closely the growth dynamics of the disease is one of the pillars toward achieving that goal.Objective: We aimed at developing a simple framework to facilitate the analysis of the growth rate (cases/day) and growth acceleration (cases/day2) of COVID-19 cases in real-time.Methods: The framework was built using the Moving Regression (MR) technique and a Hidden Markov Model (HMM). The dynamics of the pandemic was initially modeled via combinations of four different growth stages: lagging (beginning of the outbreak), exponential (rapid growth), deceleration (growth decay), and stationary (near zero growth). A fifth growth behavior, namely linear growth (constant growth above zero), was further introduced to add more flexibility to the framework. An R Shiny application was developed, which can be accessed at https://theguarani.com.br/ or downloaded from https://github.com/adamtaiti/SARS-CoV-2. The framework was applied to data from the European Center for Disease Prevention and Control (ECDC), which comprised 3,722,128 cases reported worldwide as of May 8th 2020.Results: We found that the impact of public health measures on the prevalence of COVID-19 could be perceived in seemingly real-time by monitoring growth acceleration curves. Restriction to human mobility produced detectable decline in growth acceleration within 1 week, deceleration within ~2 weeks and near-stationary growth within ~6 weeks. Countries exhibiting different permutations of the five growth stages indicated that the evolution of COVID-19 prevalence is more complex and dynamic than previously appreciated.Conclusions: These results corroborate that mass social isolation is a highly effective measure against the dissemination of SARS-CoV-2, as previously suggested. Apart from the analysis of prevalence partitioned by country, the proposed framework is easily applicable to city, state, region and arbitrary territory data, serving as an asset to monitor the local behavior of COVID-19 cases. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, severe acute respiratory syndrome, Mathematical modeling, Hidden Markov Model, growth curve analysis, moving regression Identifier An unambiguous reference to the resource within a given context 10.3389/fmed.2020.00247 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) http://socictopen.socict.org/files/original/b1769e7a9fa5361be4e27bc4d6895413.pdf 19f7e284f8fb6b14731a8a3f2ca2f4a6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Collaborative Facilitation and Collaborative Inhibition in Virtual Environments Creator An entity primarily responsible for making the resource Andrea Guazzini, Elisa Guidi, Cristina Cecchini, Eiko Yoneki Description An account of the resource Worldwide, organizations and small and medium-sized enterprises have already disruptively changed in many ways their physiological inner mechanisms, because of information and communication technologies (ICT) revolution. Nevertheless, the still ongoing COVID-19 worldwide emergency definitely promoted a wide adoption of teleworking modalities for many people around the world, making it more relevant than before to understand the real impact of virtual environments (VEs) on teamwork dynamics. From a psychological point of view, a critical question about teleworking modalities is how the social and cognitive dynamics of collaborative facilitation and collaborative inhibition would affect teamwork within VEs. This study analyzed the impact of a virtual environment (VE) on the recall of individuals and members of nominal and collaborative groups. The research assessed costs and benefits for collaborative retrieval by testing the effect of experimental conditions, stimulus materials, group size, experimental conditions order, anxiety state, personality traits, gender group composition and social interactions. A total of 144 participants were engaged in a virtual Deese-Roediger-McDermott (DRM) classical paradigm, which involved remembering word lists across two successive sessions, in one of four protocols: I-individual/nominal, I I - nominal/individual, I I I - nominal/collaborative, I V - collaborative/nominal. Results suggested, in general, a reduced collaborative inhibition effect in the collaborative condition than the nominal and individual condition. A combined effect between experimental condition and difficulty of the task appears to explain the presence of collaborative inhibition or facilitation. Nominal groups appeared to enhance the collaborative groups’ performance when virtual nominal groups come before collaborative groups. Variables such as personality traits, gender and social interactions may have a contribution to collaborative retrieval. In conclusion, this study indicated how VEs could maintain those peculiar social dynamics characterizing the participants’ engagement in a task, both working together and individually, and could affect their intrinsic motivation as well as performances. These results could be exploited in order to design brand new and evidenced-based practices, to improve teleworking procedures and workers well-being, as well as teleworking teamwork effectiveness. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource collaborative facilitation, DRM paradigm, collaborative inhibition, virtual dynamics, virtual teamwork Identifier An unambiguous reference to the resource within a given context 10.3390/fi12070118 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Information technology http://socictopen.socict.org/files/original/d660d67157be35e4e7ad7310b9a442d6.pdf 7844b7e83a86648afe23fe87bcf66e1b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Novel Combination of Vitamin C, Curcumin and Glycyrrhizic Acid Potentially Regulates Immune and Inflammatory Response Associated with Coronavirus Infections: A Perspective from System Biology Analysis Creator An entity primarily responsible for making the resource Juntao Kan, Jun Du, Molly Hood, Liang Chen, Xue Zhang, Chun Hu, Lu Zhang Description An account of the resource Novel coronaviruses (CoV) have emerged periodically around the world in recent years. The recurrent spreading of CoVs imposes an ongoing threat to global health and the economy. Since no specific therapy for these CoVs is available, any beneficial approach (including nutritional and dietary approach) is worth investigation. Based on recent advances in nutrients and phytonutrients research, a novel combination of vitamin C, curcumin and glycyrrhizic acid (VCG Plus) was developed that has potential against CoV infection. System biology tools were applied to explore the potential of VCG Plus in modulating targets and pathways relevant to immune and inflammation responses. Gene target acquisition, gene ontology and Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment were conducted consecutively along with network analysis. The results show that VCG Plus can act on 88 hub targets which are closely connected and associated with immune and inflammatory responses. Specifically, VCG Plus has the potential to regulate innate immune response by acting on NOD-like and Toll-like signaling pathways to promote interferons production, activate and balance T-cells, and regulate the inflammatory response by inhibiting PI3K/AKT, NF-κB and MAPK signaling pathways. All these biological processes and pathways have been well documented in CoV infections studies. Therefore, our findings suggest that VCG Plus may be helpful in regulating immune response to combat CoV infections and inhibit excessive inflammatory responses to prevent the onset of cytokine storm. However, further in vitro and in vivo experiments are warranted to validate the current findings with system biology tools. Our current approach provides a new strategy in predicting formulation rationale when developing new dietary supplements. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, vitamin C, Curcumin, inflammatory response, system biology, Glycyrrhizic acid Identifier An unambiguous reference to the resource within a given context 10.3390/nu12041193 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Nutrition. Foods and food supply http://socictopen.socict.org/files/original/b7e6dabea4cac946123f4508e075435b.pdf 904e7cd41ebb063e00208738043f8a0d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Coronavirus PEDV Evades Type III Interferon Response Through the miR-30c-5p/SOCS1 Axis Creator An entity primarily responsible for making the resource Changlin Wang, Lingling Shan, Shuxin Qu, Mei Xue, Keliang Wang, Fang Fu, Lu Wang, Ziqi Wang, Li Feng, Wanhai Xu, Pinghuang Liu Description An account of the resource Porcine epidemic diarrhea virus (PEDV) is an economically important pathogen that has evolved several mechanisms to evade type I IFN responses. Type III interferon (IFN-λ), an innate cytokine that primarily targets the mucosal epithelia, is critical in fighting mucosal infection in the host and has been reported to potently inhibit PEDV infection in vitro. However, how PEDV escapes IFN-λ antiviral response remains unclear. In this study, we found that PEDV infection induced significant IFN-λ expression in type I IFN-defective Vero E6 cells, but virus-induced endogenous IFN-λ did not reduce PEDV titers. Moreover, we demonstrated that PEDV escaped IFN-λ responses by substantially upregulating the suppressor of cytokine signaling protein 1 (SOCS1) expression, which impaired the induction of IFN-stimulated genes (ISGs) and dampened the IFN-λ antiviral response and facilitated PEDV replication in Vero E6 cells. We further showed that PEDV infection increased SOCS1 expression by decreasing host miR-30c-5p expression. MiR-30c-5p suppressed SOCS1 expression through targeting the 3′ untranslated region (UTR) of SOCS1. The inhibition of IFN-λ elicited ISGs expression by SOCS1 was specifically rescued by overexpression of miR-30c-5p. Collectively, our findings identify a new strategy by PEDV to escape IFN-λ-mediated antiviral immune responses by engaging the SOCS1/miR-30c axis, thus improving our understanding of its pathogenesis. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, PEDV, microRNA, SOCS- 1, IFN-λ, miR-30c-5p Identifier An unambiguous reference to the resource within a given context 10.3389/fmicb.2020.01180 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology