272 10 20655 http://socictopen.socict.org/files/original/451e58b0c2fc04a83156a737f52b5cd6.pdf 3ee50f6b9458a875010bc26e34b8b6f3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Best practices for correctly identifying coronavirus by transmission electron microscopy. Creator An entity primarily responsible for making the resource Hannah A Bullock, Cynthia S Goldsmith, Sara E Miller Description An account of the resource This guidance provides clear, concise strategies for identifying coronaviruses by transmission electron microscopy of ultrathin sections of tissues or infected tissue cultures. These include a description of virus morphology as well as cell organelles that can resemble viruses. Biochemical testing and caveats are discussed. Numerous references provide information for documentation and further study. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource coronavirus, Microbiology, coronavirus electron microscopy, coronavirus misidentification, coronavirus morphology, coronavirus ultrastructure Identifier An unambiguous reference to the resource within a given context 10.1016/j.kint.2021.01.004 Source A related resource from which the described resource is derived Kidney international http://socictopen.socict.org/files/original/840bc0ce15babbad6f26894d3a2da0ea.pdf d052efb5f83f1a3e3f4905f9339a669e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Best practices for standardized performance testing of infrared thermographs intended for fever screening. Creator An entity primarily responsible for making the resource Pejman Ghassemi, T. Joshua Pfefer, Jon P Casamento, Rob Simpson, Quanzeng Wang Description An account of the resource Infrared (IR) modalities represent the only currently viable mass fever screening approaches for outbreaks of infectious disease pandemics such as Ebola virus disease and severe acute respiratory syndrome. Non-contact IR thermometers (NCITs) and IR thermographs (IRTs) have been used for fever screening in public areas such as airports. While NCITs remain a more popular choice than IRTs, there has been increasing evidences in the literature that IRTs can provide great accuracy in estimating body temperature if qualified systems are used and appropriate procedures are consistently applied. In this study, we addressed the issue of IRT qualification by implementing and evaluating a battery of test methods for objective, quantitative assessment of IRT performance based on a recent international standard (IEC 80601-2-59). We tested two commercial IRTs to evaluate their stability and drift, image uniformity, minimum resolvable temperature difference, and radiometric temperature laboratory accuracy. Based on these tests, we illustrated how experimental and data processing procedures could affect results, and suggested methods for clarifying and optimizing test methods. Overall, the insights into thermograph standardization and acquisition methods provided by this study may improve the utility of IR thermography and aid in comparing IRT performance, thus improving the potential for producing high quality disease pandemic countermeasures. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0203302 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN http://socictopen.socict.org/files/original/e5a51d09a7089d306f2f885df5c6323b.pdf abbfb0d776766e638b84d50ba2b857e0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource BEST: improved prediction of B-cell epitopes from antigen sequences. Creator An entity primarily responsible for making the resource Jianzhao Gao, Eshel Faraggi, Yaoqi Zhou, Jishou Ruan, Lukasz Kurgan Description An account of the resource Accurate identification of immunogenic regions in a given antigen chain is a difficult and actively pursued problem. Although accurate predictors for T-cell epitopes are already in place, the prediction of the B-cell epitopes requires further research. We overview the available approaches for the prediction of B-cell epitopes and propose a novel and accurate sequence-based solution. Our BEST (B-cell Epitope prediction using Support vector machine Tool) method predicts epitopes from antigen sequences, in contrast to some method that predict only from short sequence fragments, using a new architecture based on averaging selected scores generated from sliding 20-mers by a Support Vector Machine (SVM). The SVM predictor utilizes a comprehensive and custom designed set of inputs generated by combining information derived from the chain, sequence conservation, similarity to known (training) epitopes, and predicted secondary structure and relative solvent accessibility. Empirical evaluation on benchmark datasets demonstrates that BEST outperforms several modern sequence-based B-cell epitope predictors including ABCPred, method by Chen et al. (2007), BCPred, COBEpro, BayesB, and CBTOPE, when considering the predictions from antigen chains and from the chain fragments. Our method obtains a cross-validated area under the receiver operating characteristic curve (AUC) for the fragment-based prediction at 0.81 and 0.85, depending on the dataset. The AUCs of BEST on the benchmark sets of full antigen chains equal 0.57 and 0.6, which is significantly and slightly better than the next best method we tested. We also present case studies to contrast the propensity profiles generated by BEST and several other methods. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0040104 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN http://socictopen.socict.org/files/original/b34e04fc307307c24c0f643ef8ebdc5d.pdf 0dd1826742f72c30d0a78a04e365bc0f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Betrachtungen zum Verhältnis zwischen Wildpferd (Equus ferus) und Hydruntinus (Equus hydruntinus) im Jungpleistozän und Holozän auf der Iberischen Halbinsel Creator An entity primarily responsible for making the resource Hans-Peter Uerpmann Description An account of the resource Se analizan las relaciones entre dos équidos salvajes, el caballo salvaje Equus ferus y el llamado asno salvaje europeo Equus hydruntinus, durante el pleistoceno superior con referencia a Iberia, donde habitaron ambas especies. El estudio se basa en materiales óseos de los yacimiegntos paleoliticos de Cataluña. En ellos la frecuencia relativa de los restos de E. hydruntinus frente a E. ferus varía desde el 100% al principio de la secuencia a 0% durante el último máximo glacial. Hacia finales del pleistoceno reaparece el E. hydruntinus en Cataluña. Sin embargo el caballo salvaje, E. ferus se multiplica por lo menos hasta mitades del holoceno. Esta situación se puede comparar con Anatolia, donde observamos el esperado aumento en el número de E. hydruntinus en yacimientos neolíticos y donde desaparece E. ferus hacia mitades del holoceno. El motivo de este contraste lo encontramos en la particular reducción de tamaño que observamos en Iberia entre los ejemplares de E. ferus en el pleistoceno supeior. Debido a su pequeño tamaño en el holoceno, el caballo salvaje tal vez sustituyera al asno" salvaje en su función ecológica llegando a remplazarlo en sus potenciales hábitats." Date A point or period of time associated with an event in the lifecycle of the resource 2005 Subject The topic of the resource Equidos, Holoceno, Iberia, Pleistoceno superior, ecología Source A related resource from which the described resource is derived Munibe Antropologia-Arkeologia Publisher An entity responsible for making the resource available Sociedad de Ciencias Aranzadi Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Archaeology, Auxiliary sciences of history Relation A related resource <a href="http://www.aranzadi-zientziak.org/fileadmin/docs/Munibe/200501351358AA.pdf" target="_blank" rel="noreferrer noopener">http://www.aranzadi-zientziak.org/fileadmin/docs/Munibe/200501351358AA.pdf</a> http://socictopen.socict.org/files/original/f6fc09b803a3e9a7358a71f4f3d4b713.pdf 531c77d74f699c6f7571df467b25d2be Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Better quality score compression through sequence-based quality smoothing Creator An entity primarily responsible for making the resource Yoshihiro Shibuya, Matteo Comin Description An account of the resource Abstract Motivation Current NGS techniques are becoming exponentially cheaper. As a result, there is an exponential growth of genomic data unfortunately not followed by an exponential growth of storage, leading to the necessity of compression. Most of the entropy of NGS data lies in the quality values associated to each read. Those values are often more diversified than necessary. Because of that, many tools such as Quartz or GeneCodeq, try to change (smooth) quality scores in order to improve compressibility without altering the important information they carry for downstream analysis like SNP calling. Results We use the FM-Index, a type of compressed suffix array, to reduce the storage requirements of a dictionary of k-mers and an effective smoothing algorithm to maintain high precision for SNP calling pipelines, while reducing quality scores entropy. We present YALFF (Yet Another Lossy Fastq Filter), a tool for quality scores compression by smoothing leading to improved compressibility of FASTQ files. The succinct k-mers dictionary allows YALFF to run on consumer computers with only 5.7 GB of available free RAM. YALFF smoothing algorithm can improve genotyping accuracy while using less resources. Availability https://github.com/yhhshb/yalff Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource FASTQ compression, BWT, FM-Index Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12859-019-2883-5 Source A related resource from which the described resource is derived BMC Bioinformatics Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Computer applications to medicine. Medical informatics Language A language of the resource EN http://socictopen.socict.org/files/original/6c2428fc5b03f62aa50bb138eb99363d.pdf efa87726c595f1b7198711c7eb459702 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Between COVID-19 severity and its prevention - what should rheumatologists be aware of? Creator An entity primarily responsible for making the resource Joanna Makowska, Filip Styrzyński Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.5114/reum.2021.103941 Source A related resource from which the described resource is derived Reumatologia http://socictopen.socict.org/files/original/d1a7381e702e2013d0df1acd46744cea.pdf bd785da9723669accfc3295d7dfdac57 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Between Environmental Policy and Scientific Knowledge: How Might Dryland Environments Challenge Ideas Regarding Ecological Dynamics? Creator An entity primarily responsible for making the resource Rafael Calderón-Contreras Description An account of the resource El objetivo principal de este trabajo es analizar cómo las perspectivas acerca de los ambientes semidesérticos y desérticos desafían las ideas tradicionales acerca de las dinámicas ecológicas. Para alcanzar este objetivo, el artículo se divide en tres partes: la primera analiza las características de la ecología de sistemas y la forma en la que dichos ambientes disputan los conceptos tradicionales de capacidad de carga y los postulados de área-biodiversidad y estabilidad. La segunda parte analiza el resurgimiento de la 'nueva ecología' y cómo los conceptos de no-equilibrio divergen de aquellos pertenecientes a la corriente más convencional de ecología de sistemas. Finalmente se consideran algunas características de los ambientes semidesérticos y desérticos que evidencian dicha dicotomía conceptual; esta sección busca acentuar los postulados ecológicos adoptados en el diseño e implementación de políticas en torno al manejo, administración y conservación de ambientes semidesérticos y desérticos. Date A point or period of time associated with an event in the lifecycle of the resource 2010 Subject The topic of the resource ambientes desérticos y semidesérticos, area, biodiversidad, capacidad de carga, estabilidad, nueva ecología Source A related resource from which the described resource is derived Ciencia Ergo Sum Publisher An entity responsible for making the resource available Universidad Autonoma del Estado de Mexico Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social Sciences, Science Relation A related resource <a href="http://www.redalyc.org/articulo.oa?id=10412443011" target="_blank" rel="noreferrer noopener">http://www.redalyc.org/articulo.oa?id=10412443011</a> http://socictopen.socict.org/files/original/7906f5ae231e37140574fd483430057a.pdf 25dc565dce32815fd96d302e7f93cc3f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Between flowers and fears: the new coronavirus pandemic (COVID-19) and the flower retail trade Creator An entity primarily responsible for making the resource Adilson Anacleto, Anna Paula de Araújo Bornancin, Silas Hallel Camilo Mendes, Luciane Scheuer Description An account of the resource In order to support a better understanding of the current scenario of the crisis installed by the New Coronavirus (SARS-CoV-2: COVID-19) in the flower retail trade, it is presented a descriptive exploratory research carried out between April and May 2020 with 30 flower shop managers located in the Southern region of Brazil. The results showed that the most significant impacts were the drop in the number of customers, which reduced the company’s income when compared to the values sold before the pandemic, and that the pandemic scenario generated a 45.3% reduction in financial transactions on average. Among the flower shops in this survey, 70% of flower shops were closed for an average of 21.4 days, when they were reopened with restrictions on attendance related to hours or the number of people inside the stores. The e-commerce and social media were the main tools to confront this situation, and the most used Apps were WhatsApp and Instagram. But other actions such as discounting on purchases by quantity, free delivery and marketing in the surrounding were also registered. Among the possible complementary actions in order to face this crisis and which can have positive effects, it is highlighted the online courses directed to the trade of gardening kits, the adoption of the Just In Time (JIT) methodology that can result in partnerships with local producers in order to reduce inventory costs and purchase prices, and the organization of collective purchasing groups to bargain prices with wholesalers, as well as the reduction of transportation and operational costs at Veiling in Holambra. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Social isolation, economy, ornamental plants, flower shops, ornamental horticulture Identifier An unambiguous reference to the resource within a given context 10.1590/2447-536X.v27i1.2232 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Plant culture http://socictopen.socict.org/files/original/04f32d05e57bc3e0e370d8713926ea4f.pdf 00d23fc203fe43a0ea4482f1f28a982b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Between the sea and the land: the livelihood of estuarine people in southeastern Brazil Entre o mar e a terra: modos de vida de comunidades estuarinas no sudeste do Brasil Creator An entity primarily responsible for making the resource Nivaldo Peroni, Natalia anazaki, Fabio de Castro, Vivian Gladys Oliveira Description An account of the resource The central focus of this study is to characterize and compare the livelihood strategies of two coastal communities from the estuarine region of Ribeira Valley (São Paulo State, Southeastern Brazil), analyzing the interplay among four economic activities: small-scale agriculture, fishing, tourism-related jobs, and extraction of non-timber vegetal resources. The local people of these communities are mostly Caiçara, the native inhabitants of southeastern Brazilian coast, in an Atlantic forest area. The miscegenation of Amerindians, European colonizers, and African Brazilians gave rise to the Caiçara people, whose subsistence was originally based on small-scale itinerant agriculture, small-scale fishery, and some extraction of forest products. Their livelihoods activities changed through time: agricultural practices were gradually abandoned, while fishing grew in importance. Recently, tourism-related jobs and the extraction of non-timber vegetal resources acquired a key role in the estuarine Caiçara livelihood. After an historical overview, we focus our analysis on the local factors and external pressures affecting the combination of these activities.O objetivo central deste artigo é caracterizar e comparar as estratégias dos meios de vida de duas comunidades da região estuarina do vale de Ribeira (Estado de São Paulo), analisando a inter-relação entre quatro atividades econômicas: agricultura de pequena escala, pesca, trabalhos relacionados ao turismo e extração de recursos vegetais não madeireiros. Os habitantes destas comunidades são na maior parte Caiçaras, nativos da costa sudeste do Brasil, vivendo em área do domínio Mata Atlântica. Caiçaras são descendentes de ameríndios e colonizadores europeus, com influências mais recentes de escravos africanos. Sua subsistência era baseada originalmente na agricultura itinerante de pequena escala, na pesca artesanal e, em menor grau, na extração de produtos florestais. Suas atividades de subsistência mudaram com o tempo: as práticas agrícolas foram abandonadas gradualmente, enquanto a pesca cresceu em importância. Recentemente, as atividades econômicas relacionadas ao turismo e à extração de recursos vegetais não madeireiros adquiriram um papel chave nos meios de subsistência dos Caiçaras desta região estuarina. Após uma contextualização histórica, nós focalizamos na análise dos fatores locais e das pressões externas que afetam a combinação destas atividades. Date A point or period of time associated with an event in the lifecycle of the resource 2007 Subject The topic of the resource Atlantic Forest, Mata Atlântica, Use of natural resources, Uso de recursos naturais, conservation, conservação, ecología humana, fisheries, human ecology, pesca Identifier An unambiguous reference to the resource within a given context 10.1590/S1414-753X2007000100008 Source A related resource from which the described resource is derived Ambiente & Sociedade Publisher An entity responsible for making the resource available Associação Nacional de Pós-Graduação e Pesquisa em Ambiente e Sociedade (ANPPAS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Human ecology. Anthropogeography Relation A related resource <a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S1414-753X2007000100008" target="_blank" rel="noreferrer noopener">http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S1414-753X2007000100008</a> http://socictopen.socict.org/files/original/cb2979371325181e284fb816e05c0797.pdf 44af9b77d04e4d5906ee10d542254d4e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Beware of Steroid-Induced Avascular Necrosis of the Femoral Head in the Treatment of COVID-19&mdash;Experience and Lessons from the SARS Epidemic Creator An entity primarily responsible for making the resource Zhang S, Wang C, Shi L, Xue Q Description An account of the resource Shenqi Zhang,1&ndash; 3 Chengbin Wang,3 Lei Shi,1 Qingyun Xue1,2 1Department of Orthopedics, Beijing Hospital, National Center of Gerontology, Beijing, People&rsquo;s Republic of China; 2Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, People&rsquo;s Republic of China; 3Department of Joint and Sports Medicine, Zaozhuang Municipal Hospital Affiliated to Jining Medical University, Shandong, People&rsquo;s Republic of ChinaCorrespondence: Qingyun XueBeijing Hospital, National Center of Gerontology, No. 1 Dongdan Dahua Road, Dongcheng District, Beijing, 100730, People&rsquo;s Republic of ChinaTel +8613188929900Email bjyyxqy@163.comSummary: The recent outbreak of coronavirus disease 2019 (COVID-19) has become a global epidemic. Corticosteroids have been widely used in the treatment of severe acute respiratory syndrome (SARS), and the pathological findings seen in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are very similar to those observed in severe acute respiratory syndrome-related coronavirus (SARS-CoV) infection. However, the long-term use of corticosteroids (especially at high doses) is associated with potentially serious adverse events, particularly steroid-induced avascular necrosis of the femoral head (SANFH). In today&rsquo;s global outbreak, whether corticosteroid therapy should be used, the dosage and duration of treatment, and ways for the prevention, early detection, and timely intervention of SANFH are some important issues that need to be addressed. This review aims to provide a reference for health care providers in COVID-19 endemic countries and regions.Article Focus: Hormones are a double-edged sword. This review aims to provide a reference for health care providers in coronavirus disease 2019 (COVID-19) endemic countries and regions, especially with respect to the pros and cons of corticosteroid use in the treatment of patients with COVID-19.Key Messages: In today&rsquo;s global outbreak, whether corticosteroid therapy should be used, the dosage and duration of treatment, and ways for the prevention, early detection, and timely intervention of SANFH are some important issues that need to be addressed.Strengths and Limitations: Since SARS was mainly prevalent in China at that time, many evidences in this paper came from the reports of Chinese scholars. There is a bias in the selection of data, which may ignore the differences in environment, race, living habits, medical level and so on. SANFH may be the result of multiple factors. Whether the virus itself is an independent risk factor for SANFH has not been confirmed. In this paper, through literature retrieval, some reference opinions on glucocorticoid usage, diagnosis and treatment of SANFH are given. However, due to the lack of large-scale research data support, it can not be used as the gold standard for the above problems.Keywords: COVID-19, steroid, necrosis of the femoral head, SARS Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource SARS, covid-19, steroid, necrosis of the femoral head Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Therapeutics. Pharmacology