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                <text>The Strength of Sociopreneurs in Nurturing the Rural Socioeconomic Conditions</text>
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                <text>Budi Priatna Wahyu, Santoso Hudi, Moenawar M. Ghozali</text>
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                <text>Maintaining the resilience and community life in rural areas with facing various socioeconomic problems especially the impact of the Covid-19 pandemic make social entrepreneurship is very urgent. Social entrepreneurship sees the problem as an opportunity to form a new business model. The results achieved are not only material benefits, but how the ideas put forward can have a good impact on society at large. In doing so, nurturing the rural socioeconomic problems it requires the presence of socio-preneurs who are able to bridge social needs and current services. This study aims to analyse how the strength of Socio-preneurs in nurturing the rural socioeconomic conditions with community empowerment programs in the fields of education, economics, agriculture and environment which is based on four elements, namely: social value, civil society, innovation, economic activity. The method used in this research is descriptive qualitative through field research. The results show that the strength and capacity of Socio-preneurs are very important because they act as agents of change for the environment, improve systems, find new approaches and create solutions as part of sustainability development goals (SDGs) especially in dealing with the impact of the Covid-19 pandemic for sustainability better life.</text>
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                <text>10.1051/e3sconf/202123201035</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Environmental sciences</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>TROUBLESHOOTING IN EXPRESSION AND PURIFICATION OF RECOMBINANT SEVERE ACUTE RESPIRATORY SYNDROME-ASSOCIATED CORONAVIRUS NUCLEOCAPSID PROTEIN IN Escherichia coli BL21</text>
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                <text>Budiman Bela, Fera Ibrahim, Andi Yasmon</text>
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                <text>Considering importance of N protein for study of viral pathogenesis or development of immunodiagnostic assay, wereported effects of several conditions on purity and homogeneity of recombinant SARS-CoV N protein expressed in E.coli BL21. The SARS-CoV N gene was reverse transcribed and amplified by the reverse transcription-polymerase chainreaction (RT-PCR) technique. The amplicons were cloned into pGEX-6P1 and followed by subcloning of the targetgene into pQE-80L. After inserting the recombinant plasmid (pQE80-N) into E. coli, the recombinant protein (6 x Histag-N protein fusion) was expressed by inducing the bacterial cells with 0.1-0.5 mM isopropyl-1-thio-Dgalactopyranoside(IPTG) for 1-5 h. The protein recombinant were extracted from the bacterial cells by NTT buffercontaining 0-20 mM imidazol, and followed by Ni-NTA affinity resin purification. The results showed that induction ofE. coli BL21 with 0.2 mM IPTG for 4 h and followed with lysis of bacterial cells in NTT buffer containing 10 mMimidazol were optimal conditions to obtain the pure recombinant SARS-CoV N protein.</text>
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                <text>2010</text>
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                <text>İmidazol, IPTG, N-lauroylsarcosine, Triton X, SARS-CoV N protein</text>
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                <text>Makara Seri Sains</text>
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                <text>Universitas Indonesia</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Impact of global changes in the business environment in relation to risk management</text>
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                <text>Buganová Katarína, Šimíčková Jana, Brutovský Michal</text>
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                <text>Research background: Entrepreneurial activity is largely affected by negative changes in the global business environment, as evidenced by the huge impact of the COVID 19 pandemic on the entrepreneurial activity of Slovak enterprises. It is here that the importance of proactive risk management is reaffirmed, which should be an integral part of the enterprise’s management and thus preventively assess possible risks and their consequences and be prepared to manage them and not just respond to a crisis situation. Purpose of the article: The purpose of the article is to point out the importance of risk management in business and project management in connection with the globalization of the business environment. Assess the readiness of Slovak enterprises to ensure the continuity of business activities in connection with negative changes in the business environment such as the COVID 19 pandemic. Methods: The article will be processed using basic scientific methods. The qualitative and quantitative aspects of the researched problem, comparison and generalization of conclusions will be processed through observation, analysis, comparison and synthesis, including several managerial methods for risk assessment and management. Findings &amp; Value added: Successful implementation of risk management in the enterprise and within the project activities from the point of view of prevention of crisis situations in the enterprise caused by interruption of operation as well as premature termination of projects is a means to maintain continuity and competitiveness of business activities and achieve project goals in the global market.</text>
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                <text>2021</text>
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                <text>risk management, continuity, globalisation, enterprise, changes</text>
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                <text>10.1051/shsconf/20219203004</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Social Sciences</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Adli Otopsilerde Resusitasyon Artefaktları</text>
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                <text>Bülent Şam, Esra Saka, Çiğdem Süner</text>
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                <text>Acil tıbbi müdahale uygulanmış otopsi olgularında, travma bulgularını yorumlamak güçleşmekte, ortaya çıkan artefakt lezyonların ölüme katkısının olup olmadığı tartışma konusu olabilmektedir. Bu çalışmada, İstanbul’da Ocak 1998-Ocak 2002 tarihleri arasında otopsisi yapılmış olgulara ait otopsi raporları, ayırım yapılmadan tek tek incelenmiş, resusitasyon sonucu meydana geldiğine karar verilen lezyonların yeri ve niteliği ile ortaya çıkan sorunlar, ilgili literatür bilgileri ışığında irdelenmiştir. Olguların 51’inde (%11.7) defibrilasyona bağlı ekimozlu veya ekimozsuz kırıklar, 19’unda (%4.2) yalnızca ekimoz saptanmıştır. Kırıkların en sık sol 3-4-5. kotlarda ve midklaviküler hatta oluştuğu, sternumda kırık görülme oranmm %33.33 olduğu saptanmıştır. Birçok olguda pnömotoraks testi yapılmamış olduğu için pnömotoraks oluşma sıklığı kontrol edilememiştir.  Anahtar kelimeler: Adli otopsi, kardiyopulmoner resusitasyon, artefakt lezyonlar, tıbbi uygulama hatası, sarsılmış bebek sendromu.</text>
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                <text>2003</text>
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                <text>adli otopsi, kardiyopulmoner resusitasyon, artefakt lezyonlar, tıbbi uygulama hatası, sarsılmış bebek sendromu</text>
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                <text>DOI: 10.17986/blm.200381487</text>
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                <text>Adli Tıp Bülteni</text>
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                <text>Adli Tıp Uzmanları Derneği</text>
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                <text>Medicine (General)</text>
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                <text>Editorial: Reflecting in the shade of pandemic</text>
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                <text>I hope this editorial note finds you well and healthy, especially amid the uncertainty due to COVID-19. We are concerned about our children, families, neighbors, colleagues, and ourselves. We are contending with daily reports of death presented as the centerpiece headline news while we are dealing with grief and uncertainty. The impact of this current pandemic on society, in general, is increasingly visible, and we find ourselves in a permanent state of transformation due to the dizzying proliferation of technologies. This pandemic expedites the vital role of Information and Communication Technology (ICT) that drives the modern world in education as well as in all other areas. On the other hand, as schools and higher education institutions rapidly move their learning, teaching, and assessment online in response to the worldwide pandemic, academics feel improvised, inefficiently supported, and deeply fearful.</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Social Sciences, Education</text>
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                <text>Bağımsız Denetim Sürecinin Covid-19 Salgınının Etkileri Açısından Değerlendirilmesi (Evaluation of Independent Audit Process in terms of Effects of Covid-19 Pandemic)</text>
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                <text>Burak Ali ADANA, Mehmet ÖZBİRECİKLİ</text>
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                <text>Amaç – 2019 yılının Aralık ayında Çin Halk Cumhuriyeti’nin Vuhan eyaletinde ortaya çıkan ve dahasonra hızla yayılarak tüm dünyayı etkisi altına alan Covid-19 salgınının (SARS-CoV-19), toplumsalhayata, ülkelerin ekonomilerine ve işletmelerin faaliyetlerine etkileri çok ciddi şekildehissedilmektedir. Covid-19’un, birçok alanı etkilediği gibi bağımsız denetime tabi işletmelerinbağımsız denetim süreçlerini de etkilemesi söz konusudur. Bu çalışmanın amacı Covid-19salgınının, bağımsız denetim sürecine ve bu sürecin çıktısı olan bağımsız denetçi raporu üzerindekipotansiyel etkilerini tartışma konusu ederek içinde bulunduğumuz süreçte bağımsız denetimfaaliyetini sürdüren denetim mesleği mensuplarının faaliyetlerine katkı sağlamaktır.Yöntem – Mevcut ve potansiyel etkiler, bağımsız denetim süreci ve Bağımsız DenetimStandartlarının (BDS) gereklilikleri açısından değerlendirilmiş ve bağımsız denetime tabi şirketlerinwww.kap.org.tr ve www.spk.gov.tr internet sitelerinde yayımlanan bağımsız denetçi raporlarındaCovid-19 salgınının etkilerine nasıl yer verildiği inceleme konusu edilmiştir. Bunun için sosyalbilimlerde nitel araştırma yöntemlerinden biri olan dökümantasyon tarama yöntemi kullanılmıştır.İnceleme tarihi (04.06.2020) itibariyle yayımlanmış denetçi raporlarının tümü (81 rapor) ana kütleolarak alınmış ve incelenmiştir.Bulgular – Mevcut ve potansiyel etkiler dikkate alındığında, Covid-19 salgınının, bağımsız denetimsürecine önemli etkileri olduğu ve bağımsız denetçilerin denetim sürecini planlarken ve denetçiraporunu hazırlarken bu etkileri dikkate alması gerektiği görülmektedir.Tartışma – Salgının, denetimin planlanması ve yürütülmesi, fiziksel kanıt toplama ve bağımsızdenetim sürecine önemli etkileri olduğu görülmektedir. Bu nedenle bağımsız denetçilerin denetimriskini düşürmek için denetim sürecini bu duruma uygun bir yaklaşımla planlaması ve denetçiraporunu hazırlarken bu etkileri raporuna yansıtması gerekir. Purpose – The coronavirus pandemic (Covid-19), which emerged in the Wuhan province of thePeople's Republic of China in December 2019 and later has spread rapidly to the whole world, has aserious impact on life of people, economy of countries and activity of businesses. It is inevitable thatcoronavirus pandemic affects the independent audit processes of businesses as well as many otherfields. This study aims to provide contribution with independent auditors who have conductedaudit activities nowadays by dicussing the current and potential effects of the coronavirus on theindependent audit process and the independent audit report that is the output of this process.Design/methodology/approach – The current and potential effects were evaluated in terms ofindependent audit process and requirements of International Standard on Auditing (ISA) andexamined to what extent auditors draw attention the said effects in the independent audit reports ofthe companies subject to independent audit published on the websites www.kap.org.tr andwww.spk.gov.tr. To do this, document examination method which is one of the qualitative researchmethods in social sciences is used. The universe used in the study is whole auditor’s reports (81reports) issued as of the date of investigation made for the study.Findings – Given the current and potential effects, it is seen that coronavirus has serious effects onindependent audit process and independent auditors must consider the said effects while planningaudit process and preparing auditor’s report.Discussion – It is seen that covid-19 pandemic has important effects on audit's planning andpracticing, collecting physical evidence and independent audit process. Therefore, in order to reducethe audit risk, independent auditors should plan the audit process in accordance with this situationand reflect these effects on their report when preparing their “auditor's report”.</text>
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                <text>2020</text>
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                <text>coronavirus, koronavirus, covid-19, Independent Audit, Bağımsız Denetim, auditor’s report, key audit matters, denetçi raporu, kilit denetim konuları</text>
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                <text>Korean Society of Epidemiology</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Artificial Intelligence-Empowered Mobilization of Assessments in COVID-19-Like Pandemics: A Case Study for Early Flattening of the Curve</text>
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                <text>Burak Kantarci, Murat Şimşek</text>
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                <text>The global outbreak of the Coronavirus Disease 2019 (COVID-19) pandemic has uncovered the fragility of healthcare and public health preparedness and planning against epidemics/pandemics. In addition to the medical practice for treatment and immunization, it is vital to have a thorough understanding of community spread phenomena as related research reports 17.9–30.8% confirmed cases to remain asymptomatic. Therefore, an effective assessment strategy is vital to maximize tested population in a short amount of time. This article proposes an Artificial Intelligence (AI)-driven mobilization strategy for mobile assessment agents for epidemics/pandemics. To this end, a self-organizing feature map (SOFM) is trained by using data acquired from past mobile crowdsensing (MCS) campaigns to model mobility patterns of individuals in multiple districts of a city so to maximize the assessed population with minimum agents in the shortest possible time. Through simulation results for a real street map on a mobile crowdsensing simulator and considering the worst case analysis, it is shown that on the 15th day following the first confirmed case in the city under the risk of community spread, AI-enabled mobilization of assessment centers can reduce the unassessed population size down to one fourth of the unassessed population under the case when assessment agents are randomly deployed over the entire city.</text>
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                <text>International Journal of Environmental Research and Public Health</text>
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                <text>Artificial Intelligence-Empowered Mobilization of Assessments in COVID-19-Like Pandemics: A Case Study for Early Flattening of the Curve</text>
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                <text>Burak Kantarci, Murat Simsek</text>
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                <text>The global outbreak of the Coronavirus Disease 2019 (COVID-19) pandemic has uncovered the fragility of healthcare and public health preparedness and planning against epidemics/pandemics. In addition to the medical practice for treatment and immunization, it is vital to have a thorough understanding of community spread phenomena as related research reports 17.9–30.8% confirmed cases to remain asymptomatic. Therefore, an effective assessment strategy is vital to maximize tested population in a short amount of time. This article proposes an Artificial Intelligence (AI)-driven mobilization strategy for mobile assessment agents for epidemics/pandemics. To this end, a self-organizing feature map (SOFM) is trained by using data acquired from past mobile crowdsensing (MCS) campaigns to model mobility patterns of individuals in multiple districts of a city so to maximize the assessed population with minimum agents in the shortest possible time. Through simulation results for a real street map on a mobile crowdsensing simulator and considering the worst case analysis, it is shown that on the 15th day following the first confirmed case in the city under the risk of community spread, AI-enabled mobilization of assessment centers can reduce the unassessed population size down to one fourth of the unassessed population under the case when assessment agents are randomly deployed over the entire city.</text>
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