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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Probable Secondary Infections in Households of SARS Patients in Hong Kong</text>
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                <text>Joseph T. F. Lau, Mason Lau, Jean H. Kim, Eric Wong, Hi Yi Tsui, Thomas Tsang, Tze-wai Wong</text>
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                <text>Although severe acute respiratory syndrome (SARS) is highly infectious in clinical settings, SARS has not been well examined in household settings. The household and household member attack rates were calculated for 1,214 SARS case-patients and their household members, stratified by two phases of the epidemic. A case-control analysis identified risk factors for secondary infection. Secondary infection occurred in 14.9% (22.1% versus 11% in earlier and later phases) of all households and 8% (11.7% versus 5.9% in the earlier and later phases) of all household members. Healthcare workers’ households were less likely to be affected. Risk factors from the multivariate analysis included at-home duration before hospitalization, hospital visitation to the SARS patient (and mask use during the visit), and frequency of close contact. SARS transmission at the household level was not negligible in Hong Kong. Transmission rates may be greatly reduced with precautionary measures taken by household members of SARS patients.</text>
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                <text>2004</text>
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                <text>SARS, secondary infections, Epidemiology, Hong Kong</text>
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            <name>Identifier</name>
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                <text>DOI: 10.3201/eid1002.030626</text>
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            <name>Source</name>
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                <text>Emerging Infectious Diseases</text>
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                <text>Centers for Disease Control and Prevention</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Infectious and parasitic diseases, Medicine</text>
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            <description>A language of the resource</description>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Mary  K. Yates, Payel Chatterjee, Mike Flint, Yafet Arefeayne, Damjan Makuc, Janez Plavec, Christina F. Spiropoulou, Katherine  L. Seley-Radtke</text>
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            <description>An account of the resource</description>
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                <text>Due to their ability to inhibit viral DNA or RNA replication, nucleoside analogues have been used for decades as potent antiviral therapeutics. However, one of the major limitations of nucleoside analogues is the development of antiviral resistance. In that regard, flexible nucleoside analogues known as &amp;#8220;fleximers&amp;#8221; have garnered attention over the years due to their ability to survey different amino acids in enzyme binding sites, thus overcoming the potential development of antiviral resistance. Acyclic fleximers have previously demonstrated antiviral activity against numerous viruses including Middle East Respiratory Syndrome coronavirus (MERS-CoV), Ebola virus (EBOV), and, most recently, flaviviruses such as Dengue (DENV) and Yellow Fever Virus (YFV). Due to these interesting results, a Structure Activity Relationship (SAR) study was pursued in order to analyze the effect of the pyrimidine functional group and acyl protecting group on antiviral activity, cytotoxicity, and conformation. The results of those studies are presented herein.</text>
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                <text>2019</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>nucleoside, SAR, filovirus, Flavivirus, fleximers</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.3390/molecules24173184</text>
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          <element elementId="48">
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            <description>A related resource from which the described resource is derived</description>
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                <text>Molecules</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Organic chemistry</text>
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            <description>A language of the resource</description>
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                <text>EN</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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            <description>A name given to the resource</description>
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                <text>Probióticos y Conservadores Naturales en Alimentos Probióticos y Conservadores Naturales en Alimentos</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>M. Bautista-Justo, R. Salcedo-Hernández, H. Vázquez-Acosta, J. E. Barboza-Corona</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Los probióticos son alimentos que contienen bacterias que proporcionan un beneficio a la salud de quienes los consumen. Estas bacterias pueden producir proteínas llamadas bacteriocinas, que actúan como agentes antibacterianos. Las bacteriocinas pueden, además de proteger al hospedero contra el ataque de bacterias patógenas, también servir como bioconservadores en alimentos. Hasta ahora, la Nisina es la única bacteriocina que se usa comercialmente en la conservación de alimentos; sin embargo, existen otras con uso potencial como bioconservadores. En este trabajo analizamos aspectos generales de los probióticos, de los conservadores naturales, de las bacteriocinas tanto producidas por bacterias lácticas como por una bacteria que es bioinsecticida.Probiotics contain bacteria that provide benefits to the consumer’s health. Probiotic bacteria may produce proteins called bacteriocins which act as anti-microbial agents. Bacteriocins protect not only consumer against food-borne pathogenic bacteria, but also can play a role as preservatives in food. Currently, Nisin is the only bacteriocin used as a food additive, nevertheless there are other bacteriocins with a potential use as preservatives. In this work, a general overview is presented of probiotics, natural preservatives, bacteriocins from lacticbacteria, and those produced by aninsecticidal bacterium.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2012</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Bacillus thuringiensis, Bacterias lácticas, Bacteriocinas, Bioconservadores, Bioinsecticida, Probióticos</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Acta Universitaria</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Universidad de Guanajuato</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Social Sciences, Science (General)</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://www.actauniversitaria.ugto.mx/index.php/acta/article/view/224" target="_blank" rel="noreferrer noopener"&gt;http://www.actauniversitaria.ugto.mx/index.php/acta/article/view/224&lt;/a&gt;</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Problem Based Learning Terintegrasi STEM Di Era Pandemi Covid-19 Untuk Meningkatkan Keterampilan Berpikir Kritis Siswa</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Clarissa Desyana Putri, Indarini Dwi Pursitasari*, Bibin Rubini</text>
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            <description>An account of the resource</description>
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                <text>The COVID-19 pandemic has changed the learning system in schools. The learning that initially took place in class spontaneously turned into online learning. This change requires teachers to be more creative in designing learning. This study aims to improve students’ critical thinking skills through online problem-based learning integrated into science, technology, engineering, and mathematics (PBL-STEM). The research was conducted on students of class X IPA (Natural Science) in a high school in Cianjur with a Non-Equivalent Pretest-Posttest Control Group design. The research data were collected using a test of critical thinking skills in six valid essay questions with a reliability coefficient of 0.913. Besides, students’ responses to the application of PBL-STEM learning were collected through a questionnaire. The collected data were processed descriptively and inferentially. The results showed that the online application of PBL-STEM went well, and there was an increase in critical thinking skills with an N-gain of 72%. The highest gain is on the indicator of explanation, and the lowest is evaluation. The results of the significance test showed that the increase in students’ critical thinking skills through PBL-STEM learning was more significant than PBL learning. Students also responded well to the implementation of PBL-STEM in learning during the COVID-19 pandemic by 81%.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>problem-based learning, keterampilan berpikir kritis, usaha dan energi, science technology engineering mathematic</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.24815/jipi.v4i2.17859</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Education</text>
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                <text>Vários produtos químicos sintéticos são utilizados em larga escala em nossa sociedade de consumo e estão sobre forte investigação quanto a seus efeitos sobre os seres humanos e a fauna. Muitos programas de pesquisa mostram que a extensão deste impacto pode estar levando a drásticas alterações hormonais nas populações humanas, uma diminuição significativa da fertilidade masculina e o aumento da ocorrência de vários tipos de câncer. Apesar da abrangência destes estudos, poucas informações estão disponíveis sobre o tema, mesmo para estudantes de Ciências Biológicas ou de Saúde. O texto, em forma de ensaio, surgiu como material de apoio didático nas aulas ministradas pelo autor transformado em uma síntese explicativa. Além disso, o objetivo principal é instigar o leitor a procurar mais leituras e questionamentos sobre este importante tema.</text>
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                <text>En español Los problemas ambientales constituyen una preocupación creciente en las sociedades humanas. La Ecología, considerada como una ciencia teórica diseñada sólo para grupos académicos restringidos, adquiere ahora un valor práctico y sin duda será el mayor problema comercial que habrá que resolver en el siglo XXI. En inglés Environmental problems constitute an increasing concern in human societies. Ecology, regarded as a theoretical science designed for only restricted academic groups, now acquires practical value and will, without the shadow of a doubt, constitute the most important commercial problem which will have to be solved in the Century to come.</text>
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                <text>Relaciones Internacionales</text>
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                <text>Universidad Autónoma de Madrid.</text>
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                <text>&lt;a href="https://revistas.unlp.edu.ar/RRII-IRI/article/view/1789" target="_blank" rel="noreferrer noopener"&gt;https://revistas.unlp.edu.ar/RRII-IRI/article/view/1789&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>PROBLEMAS ASOCIADOS AL RENDIMIENTO AGRÍCOLA DE LA CAÑA DE AZÚCAR EN LA COOPERATIVA POTRERILLO, PROVINCIA SANCTI SPÍRITUS</text>
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                <text>Víctor Caraballoso Torrecilla, Evelio Concepción Cruz, Remberto G. Nápoles Alberto, Leydi Morales Fundora, Osmany Cruz Coca, Yudith Viñas Quintero</text>
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                <text>Los bajos rendimientos en muchas de las áreas cañeras, han caracterizado a la  agroindustria azucarera cubana en los últimos años. El siguiente trabajo se desarrolló  durante los años 2013 y 2014 en la Unidad Básica de Producción Cooperativa  Potrerillo, ubicada al centro de la provincia, tributaria a la Unidad Empresarial de Base  Melanio Hernández, en Tuinucú, Empresa Azucarera de Sancti Spíritus; el mismo tuvo como objetivo definir losproblemas críticos asociados al rendimiento agrícola de la caña  de azúcar y las acciones inmediatas en ejecuciónpara su solución, con los pronósticos  para su recuperación.Para ello se realizó un diagnóstico participativo y se identificaron  15 problemas fundamentalesque afectaron demanera directa el rendimiento de la caña  de azúcar, con la presencia de todos los cooperativistas,a partir de estosel grupo de  expertos y los cooperativistas, confeccionaron la matriz de Vester; con esta herramienta  se determinaron y clasificaron a partir del tipo de relaciones entre las variables, los  problemas críticos, activos, pasivos e independientes. A través de una ecuación de  regresión, se logró predecir la recuperación por años del rendimiento agrícola de la  Cooperativa, sostenible a partir del 2017.</text>
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                <text>Caña de Azúcar, Pronóstico, diagnóstico, rendimiento agrícola</text>
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                <text>Centro Azúcar</text>
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                <text>Universidad Central Marta Abreu" de Las Villas"</text>
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                <text>Special industries and trades</text>
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                <text>&lt;a href="http://centroazucar.uclv.edu.cu/index.php/centro_azucar/article/view/220" target="_blank" rel="noreferrer noopener"&gt;http://centroazucar.uclv.edu.cu/index.php/centro_azucar/article/view/220&lt;/a&gt;</text>
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