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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>YUCA: PAN Y CARNE, UNA ALTERNATIVA POTENCIAL PARA HACER FRENTE AL HAMBRE OCULTA</text>
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                <text>Camilo Ernesto López Carrascal, Paula Diaz Tatis</text>
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                <text>Uno de los retos que encara la humanidad es asegurar la alimentación y la adecuada nutrición para los cerca de ocho billones de habitantes del planeta. Las raíces de yuca constituyen la cuarta fuente más importante de calorías para la población humana siendo uno de los pilares de la seguridad alimentaria. Las raíces de yuca no poseen atributos nutricionales adecuados. Aunque existen variedades con valores relativamente altos de estos compuestos, sus valores están lejos de los necesarios para asegurar los requerimientos mínimos de la población humana. Las hojas de yuca poseen valores altos de contenido proteico, minerales y vitaminas, por lo que representan una fuente nutricional alternativa. Sin embargo, el consumo de hojas de yuca en América Latina es escaso o nulo como consecuencia de los altos niveles de cianuro que poseen. En algunos países de África y Asia las hojas se consumen a través de diversas recetas que incluye su cocción, eliminando así una gran cantidad del contenido cianógeno. En esta revisión se presenta un panorama general de la importancia nutricional de la yuca, las diferentes estrategias de mejoramiento genético clásico y no convencional destinados a incrementar los contenidos nutricionales de raíces y la importancia de la explotación de la variabilidad intrínseca de la yuca como una fuente de variedades y genes que puedan contribuir a la implementación de estrategias encaminadas a desarrollar materiales con los requerimientos nutricionales adecuados. Finalmente, se presenta el potencial que tienen las hojas de yuca para ser empleadas dentro de programas complementarios destinados a mejorar la calidad nutricional de la población humana.</text>
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                <text>2021</text>
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                <text>Agricultura, Alimentación, Diversidad, almidón, desnutrición</text>
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                <text>Acta Biológica Colombiana</text>
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                <text>Universidad Nacional de Colombia</text>
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                <text>Biology (General)</text>
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                <text>&lt;a href="https://revistas.unal.edu.co/index.php/actabiol/article/view/84569" target="_blank" rel="noreferrer noopener"&gt;https://revistas.unal.edu.co/index.php/actabiol/article/view/84569&lt;/a&gt;</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Z-Control on COVID-19-Exposed Patients in Quarantine</text>
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                <text>Nita H. Shah, Nisha Sheoran, Ekta Jayswal</text>
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                <text>In this paper, a mathematical model for diabetic or hypertensive patients exposed to COVID-19 is formulated along with a set of first-order nonlinear differential equations. The system is said to exhibit two equilibria, namely, exposure-free and endemic points. The reproduction number is obtained for each equilibrium point. Local stability conditions are derived for both equilibria, and global stability is studied for the endemic equilibrium point. This model is investigated along with Z-control in order to eliminate chaos and oscillation epidemiologically showing the importance of quarantine in the COVID-19 environment.</text>
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                <text>2020</text>
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                <text>10.1155/2020/7876146</text>
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                <text>International Journal of Differential Equations</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Hindawi Limited</text>
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                <text>Mathematics</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Zarathustra (Un)Vaccinated</text>
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                <text>Zlatomir  Zlatanov, Stanimir Panayotov</text>
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            <description>An account of the resource</description>
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                <text>Author(s): Zlatomir Zlatanov | Златомир Златанов  Title (English): Zarathustra (Un)Vaccinated  Title (Bulgarian): (Не)ваксинираният Заратустра  Translated by (Bulgarian to English): Stanimir Panayotov | Станимир Панайотов  Journal Reference: Identities: Journal for Politics, Gender and Culture  Publisher: Institute of Social Sciences and Humanities - Skopje    Page Range: 90-96  Page Count: 7  Citation (English): Zlatomir Zlatanov, “Zarathustra (Un)Vaccinated,” translated from the Bulgarian by Stanimir Panayotov, Identities: Journal for Politics, Gender and Culture, Vol. 17, No. 1 (Summer 2020): 90-95.  Citation (Bulgarian): Златомир Златанов, “(Не)ваксинираният Заратустра,” Identities: Journal for Politics, Gender and Culture, Vol. 17, No. 1 (Summer 2020): 90-96.</text>
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                <text>2020</text>
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                <text>covid-19, Pandemic</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Identities</text>
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                <text>Institute of Social Sciences and Humanities - Skopje</text>
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                <text>Social Sciences</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>ZCURVE_V: a new self-training system for recognizing protein-coding genes in viral and phage genomes</text>
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                <text>Zhang Chun-Ting, Guo Feng-Biao</text>
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            <description>An account of the resource</description>
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                <text>Abstract Background It necessary to use highly accurate and statistics-based systems for viral and phage genome annotations. The GeneMark systems for gene-finding in virus and phage genomes suffer from some basic drawbacks. This paper puts forward an alternative approach for viral and phage gene-finding to improve the quality of annotations, particularly for newly sequenced genomes. Results The new system ZCURVE_V has been run for 979 viral and 212 phage genomes, respectively, and satisfactory results are obtained. To have a fair comparison with the currently available software of similar function, GeneMark, a total of 30 viral genomes that have not been annotated by GeneMark are selected to be tested. Consequently, the average specificity of both systems is well matched, however the average sensitivity of ZCURVE_V for smaller viral genomes (&lt; 100 kb), which constitute the main parts of viral genomes sequenced so far, is higher than that of GeneMark. Additionally, for the genome of Amsacta moorei entomopoxvirus, probably with the lowest genomic GC content among the sequenced organisms, the accuracy of ZCURVE_V is much better than that of GeneMark, because the later predicts hundreds of false-positive genes. ZCURVE_V is also used to analyze well-studied genomes, such as HIV-1, HBV and SARS-CoV. Accordingly, the performance of ZCURVE_V is generally better than that of GeneMark. Finally, ZCURVE_V may be downloaded and run locally, particularly facilitating its utilization, whereas GeneMark is not downloadable. Based on the above comparison, it is suggested that ZCURVE_V may serve as a preferred gene-finding tool for viral and phage genomes newly sequenced. However, it is also shown that the joint application of both systems, ZCURVE_V and GeneMark, leads to better gene-finding results. The system ZCURVE_V is freely available at: http://tubic.tju.edu.cn/Zcurve_V/. Conclusion ZCURVE_V may serve as a preferred gene-finding tool used for viral and phage genomes, especially for anonymous viral and phage genomes newly sequenced.</text>
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                <text>2006</text>
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                <text>DOI: 10.1186/1471-2105-7-9</text>
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              <elementText elementTextId="6699">
                <text>BMC Bioinformatics</text>
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                <text>BMC</text>
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                <text>Biology (General), Computer applications to medicine. Medical informatics</text>
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                <text>EN</text>
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                <text>Juan-Carlos eSaiz, Ángela eVázquez-Calvo, Ana Belen Blazquez, Teresa eMerino-Ramos, Estela eEscribano-Romero, Miguel A. Martín-Acebes</text>
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                <text>Since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: West Nile, Influenza A, avian flu, dengue, Chikungunya, SARS, MERS, Ebola, and now Zika, the latest newcomer. Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, was identified in 1947 in a sentinel monkey in Uganda, and later on in humans in Nigeria. The virus was mainly confined to the African continent until it was detected in south-east Asia the 1980´s, then in the Micronesia in 2007 and, more recently in the Americas in 2014, where it has displayed an explosive spread, as advised by the World Health Organization (WHO), which resulted in the infection of hundreds of thousands of people. ZIKV infection was characterized by causing a mild disease presented with fever, headache, rash, arthralgia, and conjunctivitis, with exceptional reports of an association with Guillain-Barre syndrome (GBS) and microcephaly. However, since the end of 2015, an increase in the number of GBS associated cases and an astonishing number of microcephaly in foetus and new-borns in Brazil have been related to ZIKV infection, raising serious worldwide public health concerns. Clarifying such worrisome relationships is, thus, a current unavoidable goal. Here, we extensively review what is currently known about ZIKV, from molecular biology, transmission routes, ecology and epidemiology, to clinical manifestations, pathogenesis, diagnosis, prophylaxis and public health.</text>
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                <text>Frontiers in Microbiology</text>
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                <text>Zinc Oxide Nanoparticles and Zinc Sulfate Impact Physiological Parameters and Boosts Lipid Peroxidation in Soil Grown Coriander Plants (&lt;i&gt;Coriandrum sativum&lt;/i&gt;)</text>
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                <text>Norma Ruiz-Torres, Antonio Flores-Naveda, Enrique  Díaz Barriga-Castro, Neymar Camposeco-Montejo, Sonia Ramírez-Barrón, Fernando Borrego-Escalante, Guillermo Niño-Medina, Agustín Hernández-Juárez, Carlos Garza-Alonso, Pablo Rodríguez-Salinas, Josué  I. García-López</text>
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                <text>The objective of this study was to determine the oxidative stress and the physiological and antioxidant responses of coriander plants (Coriandrum sativum) grown for 58 days in soil with zinc oxide nanoparticles (ZnO NPs) and zinc sulfate (ZnSO4) at concentrations of 0, 100, 200, 300, and 400 mg of Zn/kg of soil. The results revealed that all Zn compounds increased the total chlorophyll content (CHLt) by at least 45%, compared to the control group; however, with 400 mg/kg of ZnSO4, chlorophyll accumulation decreased by 34.6%. Zn determination by induction-plasma-coupled atomic emission spectrometry (ICP–AES) showed that Zn absorption in roots and shoots occurred in plants exposed to ZnSO4 at all concentrations, which resulted in high levels of hydrogen peroxide (H2O2) and malondialdehyde (MDA). Only at 400 mg/kg of ZnSO4, a 78.6% decrease in the MDA levels was observed. According to the results, the ZnSO4 treatments were more effective than the ZnO NPs to increase the antioxidant activity of catalase (CAT), ascorbate peroxidase (APX), and peroxidases (POD). The results corroborate that phytotoxicity was higher in plants subjected to ZnSO4 compared to treatments with ZnO NPs, which suggests that the toxicity was due to Zn accumulation in the tissues by absorbing dissolved Zn++ ions.</text>
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                <text>2021</text>
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            <description>The topic of the resource</description>
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                <text>Enzymatic activity, Lipid Peroxidation, Nano fertilizer, photosynthetic pigments, plant uptake</text>
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                <text>10.3390/molecules26071998</text>
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                <text>Molecules</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
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                <text>Organic chemistry</text>
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                <text>&lt;a href="https://www.mdpi.com/1420-3049/26/7/1998" target="_blank" rel="noreferrer noopener"&gt;https://www.mdpi.com/1420-3049/26/7/1998&lt;/a&gt;</text>
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              <description>An account of the resource</description>
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                <text>Zinc supplementation for males during COVID-19: Is it beneficial?</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Nagwa A Sabri, Areej Mohamed Ateya</text>
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                <text>10.1016/j.mehy.2020.110403</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture.</text>
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              <elementText elementTextId="4025">
                <text>Aartjan J. W. te Velthuis, Sjoerd H E van den Worm, Amy C. Sims, Ralph S. Baric, Eric J. Snijder, Martijn J van Hemert</text>
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                <text>Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with viral polyprotein processing. In this study we demonstrate that the combination of Zn(2+) and PT at low concentrations (2 µM Zn(2+) and 2 µM PT) inhibits the replication of SARS-coronavirus (SARS-CoV) and equine arteritis virus (EAV) in cell culture. The RNA synthesis of these two distantly related nidoviruses is catalyzed by an RNA-dependent RNA polymerase (RdRp), which is the core enzyme of their multiprotein replication and transcription complex (RTC). Using an activity assay for RTCs isolated from cells infected with SARS-CoV or EAV--thus eliminating the need for PT to transport Zn(2+) across the plasma membrane--we show that Zn(2+) efficiently inhibits the RNA-synthesizing activity of the RTCs of both viruses. Enzymatic studies using recombinant RdRps (SARS-CoV nsp12 and EAV nsp9) purified from E. coli subsequently revealed that Zn(2+) directly inhibited the in vitro activity of both nidovirus polymerases. More specifically, Zn(2+) was found to block the initiation step of EAV RNA synthesis, whereas in the case of the SARS-CoV RdRp elongation was inhibited and template binding reduced. By chelating Zn(2+) with MgEDTA, the inhibitory effect of the divalent cation could be reversed, which provides a novel experimental tool for in vitro studies of the molecular details of nidovirus replication and transcription.</text>
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                <text>DOI: 10.1371/journal.ppat.1001176</text>
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                <text>PLoS Pathogens</text>
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                <text>Public Library of Science (PLoS)</text>
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                <text>Biology (General), Immunologic diseases. Allergy</text>
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            <description>A language of the resource</description>
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              <description>An account of the resource</description>
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                <elementText elementTextId="88122">
                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Zona costera:  ecología, economía y política</text>
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                <text>Alejandro Toledo</text>
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                <text>Iztapalapa</text>
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                <text>Universidad Autónoma Metropolitana Unidad Iztapalapa</text>
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                <text>&lt;a href="https://revistaiztapalapa.izt.uam.mx/index.php/izt/article/view/816" target="_blank" rel="noreferrer noopener"&gt;https://revistaiztapalapa.izt.uam.mx/index.php/izt/article/view/816&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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                <text>ZONAS CON POTENCIAL AGROTURÍSTICO EN LA REGIÓN CITRÍCOLA DE NUEVO LEÓN, MÉXICO: UN ANÁLISIS A PARTIR DEL ÁLGEBRA DE MAPAS</text>
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                <text>Brenda Alcalá Escamilla, Álvaro López López</text>
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                <text>La Región Citrícola de Nuevo León se caracteriza por una tradición agrícola de más de un siglo en el cultivo de naranjas, mandarinas y toronjas. No obstante, en los últimos años ha buscado diversificar y eslabonar la agricultura con el turismo. El objetivo del estudio fue identificar a través de un análisis de álgebra de mapas zonas con potencial agroturístico mediante la ubicación, coincidencia y concentración de la citricultura, la agroindustria, los recursos de interés turístico, la infraestructura básica, los servicios de vinculación turística y la accesibilidad.</text>
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                <text>Cuadernos de Turismo</text>
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                <text>Universidad de Murcia</text>
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                <text>Geography. Anthropology. Recreation, Recreation. Leisure</text>
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                <text>&lt;a href="http://www.redalyc.org/articulo.oa?id=39851043001" target="_blank" rel="noreferrer noopener"&gt;http://www.redalyc.org/articulo.oa?id=39851043001&lt;/a&gt;</text>
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