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                  <text>Dominio científico: Coronavirus</text>
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                <text>Biorisk assessment for infrastructure &amp; biosafety requirements for the laboratories providing coronavirus SARS-CoV-2/(COVID-19) diagnosis</text>
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                <text>Devendra T Mourya, Pragya D Yadav, Anita Shete, Gajanan Sapkal, Nivedita Gupta, Sujeet Kumar M Belani</text>
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                <text>Novel coronavirus infection [coronavirus disease 2019 (COVID-19)] has spread to more than 203 countries of various regions including Africa, America, Europe, South East Asia and Western Pacific. The WHO had declared COVID-19 as the global public health emergency and subsequently as pandemic because of its worldwide spread. It is now one of the top-priority pathogens to be dealt with, because of high transmissibility, severe illness and associated mortality, wide geographical spread, lack of control measures with knowledge gaps in veterinary and human epidemiology, immunity and pathogenesis. The quick detection of cases and isolating them has become critical to contain it. To meet the increasing demand of the diagnostic services, it is necessary to enhance and expand laboratory capabilities since existing laboratories cannot meet the emerging demand. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a BSL-2 (Biosafety Level 2) agent and needs to be handled in biosafety cabinet using standard precautions. This review highlights minimum requirements for the diagnostic laboratories opting testing of material for the diagnosis of COVID-19 and associated biorisk to the individuals and to the community.</text>
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                <text>2020</text>
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                <text>biorisk - biosafety - diagnosis - infrastructure - laboratories - novel coronavirus</text>
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                <text>DOI: 10.4103/ijmr.IJMR_763_20</text>
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                <text>Indian Journal of Medical Research</text>
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                <text>Wolters Kluwer Medknow Publications</text>
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                <text>Medicine</text>
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        <name>Dublin Core</name>
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            <name>Title</name>
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                <text>Communicating with people with hearing loss: COVID-19 and beyond</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Devina Maru, Jack Stancel-Lewis, Graham Easton, William EJ Leverton</text>
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            <name>Date</name>
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                <text>2021</text>
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                <text>covid-19, PRIMARY HEALTH CARE, General practice, hearing loss, ENT, Family medicine, deafness, consultation skills</text>
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            <name>Identifier</name>
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                <text>10.3399/BJGPO.2020.0174</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
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                <text>Coronavirus envelope protein: current knowledge</text>
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            <name>Creator</name>
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                <text>Dewald Schoeman, Burtram C. Fielding</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and mammals but, in the last few decades, have shown to be capable of infecting humans as well. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and, more recently, Middle-East respiratory syndrome (MERS) has demonstrated the lethality of CoVs when they cross the species barrier and infect humans. A renewed interest in coronaviral research has led to the discovery of several novel human CoVs and since then much progress has been made in understanding the CoV life cycle. The CoV envelope (E) protein is a small, integral membrane protein involved in several aspects of the virus’ life cycle, such as assembly, budding, envelope formation, and pathogenesis. Recent studies have expanded on its structural motifs and topology, its functions as an ion-channelling viroporin, and its interactions with both other CoV proteins and host cell proteins. Main body This review aims to establish the current knowledge on CoV E by highlighting the recent progress that has been made and comparing it to previous knowledge. It also compares E to other viral proteins of a similar nature to speculate the relevance of these new findings. Good progress has been made but much still remains unknown and this review has identified some gaps in the current knowledge and made suggestions for consideration in future research. Conclusions The most progress has been made on SARS-CoV E, highlighting specific structural requirements for its functions in the CoV life cycle as well as mechanisms behind its pathogenesis. Data shows that E is involved in critical aspects of the viral life cycle and that CoVs lacking E make promising vaccine candidates. The high mortality rate of certain CoVs, along with their ease of transmission, underpins the need for more research into CoV molecular biology which can aid in the production of effective anti-coronaviral agents for both human CoVs and enzootic CoVs.</text>
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                <text>2019</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="10257">
                <text>coronavirus, envelope protein, topology, assembly, Budding, Viroporin</text>
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            <name>Identifier</name>
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              <elementText elementTextId="10258">
                <text>DOI: 10.1186/s12985-019-1182-0</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Virology Journal</text>
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                <text>BMC</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Infectious and parasitic diseases</text>
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            <description>A language of the resource</description>
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                <text>EN</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Teachers’ Encounter of Online Learning: Challenges and Support System</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Dewi Listia Apriliyanti, Gartika Pandu Bhuana</text>
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                <text>The pandemic of COVID-19 situation has converted the teaching and learning process from face-to-face interaction in the classroom into virtual classroom environment. This condition caused challenges for many parties, including teachers as the main agent in the classroom. This study is intended to find out the teachers’ barriers and supports in conducting online learning. A descriptive qualitative method design through an open-ended questionnaire was chosen. Interview were also used to triangulate the data. Twenty-one teachers from sub-urban areas in Cimahi and Bandung were selected as the participants. The findings revealed three issues becoming teachers' challenges, namely, technology, course content, and students. In the first issue, the classic problem of online learning occurred, which was internet connectivity. The second problem was that the teachers had obstacles in making adjustments to design, deliver, and follow-up the material. Then the last issue was the students’ participation as well as technological access. Regarding the supports, the teachers had gained back up from the government, school, and parent in conducting online learning. Furthermore, this study recommended three optional solutions to help the teacher facing their barriers in virtual teaching, in terms of students’ participation in online learning, learning materials, and facilities in supporting the learning activities.</text>
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                <text>2021</text>
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                <text>Challenges, online learning, teachers, support system</text>
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                <text>10.33369/jeet.5.1.110-122</text>
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                <text>Journal of English Education and Teaching</text>
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                <text>UNIB Press</text>
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                <text>Theory and practice of education, English language</text>
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                  <text>Agricultura sostenible</text>
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                <text>ASPECTOS BÁSICOS DE REFRIGERACIÓN PARA LA AGROINDUSTRIA BASIC ASPECTS OF REFRIGERATION FOR THE AGROINDUSTRY</text>
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                <text>Deyanira Muñoz-Muñoz, GERARDO CABRERA CIFUENTES</text>
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            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="173994">
                <text>El presente trabajo expone los fundamentos más comunes en que se basan los sistemas de refrigeración solar para las aplicaciones agroindustriales.The present work exposes the most common principles that the systems of solar refrigeration are based for agroindustrials applications.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="173995">
                <text>2008</text>
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            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="173996">
                <text>Refrigerator, Solar Refrigeration, Transferencia de calor, heat transfer, radiación solar, refrigeración solar, refrigerador, solar radiation</text>
              </elementText>
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          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="173997">
                <text>Biotecnología en el Sector Agropecuario y Agroindustrial</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
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                <text>Universidad del Cauca</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
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            <elementTextContainer>
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                <text>Agriculture (General), Biotechnology</text>
              </elementText>
            </elementTextContainer>
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            <name>Relation</name>
            <description>A related resource</description>
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                <text>&lt;a href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;amp;pid=S1692-35612008000200011" target="_blank" rel="noreferrer noopener"&gt;http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;amp;pid=S1692-35612008000200011&lt;/a&gt;</text>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88121">
                  <text>Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88122">
                  <text>Dominio científico: Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
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      </elementSetContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
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        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="185061">
                <text>Prácticas y reflexiones sobre el ambiente: miradas desde la formación de maestros de biología</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="185062">
                <text>Deysi Serrato Rodríguez</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="185063">
                <text>El artículo presenta algunas reflexiones y prácticas vinculadas a los futuros maestros de biología de la Universidad Pedagógica Nacional, particularmente en relación con el ambiente y sus propuestas para abordarlo en la escuela. Entre otras, se posicionan comprensiones alrededor del ambiente en tanto recurso, biosfera, experiencia y capital natural, tejiendo relaciones con la ecología, la economía y la política; igualmente, se sustenta la importancia de las ciudadanías ambientales para el cuidado y protección del ambiente y la naturaleza para, finalmente, proponer una mirada distinta desde la enseñanza ambiental y la experiencia de los sujetos.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="185064">
                <text>2021</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="185065">
                <text>Ambiente, Experiência, enseñanza ambiental, maestro, pedagogía</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="185066">
                <text>10.36737/01230425.n40.2021.2460</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="185067">
                <text>Educación y Ciudad</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="185068">
                <text>Instituto para la Investigación educativa y el Desarrollo Pedagógico - IDEP</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="185069">
                <text>Special aspects of education, Education</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="185070">
                <text>&lt;a href="https://revistas.idep.edu.co/index.php/educacion-y-ciudad/article/view/2460" target="_blank" rel="noreferrer noopener"&gt;https://revistas.idep.edu.co/index.php/educacion-y-ciudad/article/view/2460&lt;/a&gt;</text>
              </elementText>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23687">
                <text>Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23688">
                <text>Deyun Wang, Yew  Kwang Ong, Xinni Xu</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23689">
                <text>Abstract The coronavirus disease (COVID-19) pandemic has led to a global struggle to cope with the sheer numbers of infected persons, many of whom require intensive care support or eventually succumb to the illness. The outbreak is managed by a combination of disease containment via public health measures and supportive care for those who are affected. To date, there is no specific anti-COVID-19 treatment. However, the urgency to identify treatments that could turn the tide has led to the emergence of several investigational drugs as potential candidates to improve outcome, especially in the severe to critically ill. While many of these adjunctive drugs are being investigated in clinical trials, professional bodies have attempted to clarify the setting where the use of these drugs may be considered as off-label or compassionate use. This review summarizes the clinical evidence of investigational adjunctive treatments used in COVID-19 patients as well as the recommendations of their use from guidelines issued by international and national organizations in healthcare.</text>
              </elementText>
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          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23690">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23691">
                <text>corticosteroids, chloroquine, Lopinavir/ritonavir, adjunctive treatment, remdesivir, COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="23692">
                <text>DOI: 10.1186/s40779-020-00251-x</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="23693">
                <text>Military Medical Research</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="23694">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="23695">
                <text>Medicine (General), Military Science</text>
              </elementText>
            </elementTextContainer>
          </element>
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  </item>
  <item itemId="17165" public="1" featured="0">
    <fileContainer>
      <file fileId="17163">
        <src>http://socictopen.socict.org/files/original/0a73ee402aae0989e260975d17b44504.pdf</src>
        <authentication>4bab00b5ccdb7b40480c54f8a7bee570</authentication>
      </file>
    </fileContainer>
    <collection collectionId="2">
      <elementSetContainer>
        <elementSet elementSetId="1">
          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88121">
                  <text>Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88122">
                  <text>Dominio científico: Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="143500">
                <text>DETERMINAÇÃO DAS DIMENSÕES DE UM BIODIGESTOR EM FUNÇÃO DA PROPORÇÃO GÁS/FASE LÍQUIDA</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="143501">
                <text>Deyvid da Silva Ribeiro</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="143502">
                <text>Devido ao risco de contaminação ambiental através da má manipulação dos excrementos animais produzidos pela pecuária, se faz necessário buscar alternativas eficientes e de baixo custo para resolver este problema. Entre as diversas soluções, FAO (1995) recomenda o Biodigestor como uma alternativa viável e prática. Entre os benefícios gerados pelo o biodigestor podemos citar: produção de biogás, descontaminação biológica e química dos dejetos animais e a geração de biofertilizante (CIPAV, [2004?]; Fregoso et al, 2001; Marchaim, 1992; Botero e Preston, 1986). Por tanto, esse presente trabalho foi realizado com o objetivo de determinar as dimensões de um biodigestor tubular em função da proporção gás/fase líquida desejada. Para esse fim, foram utilizadas as recomendações de Ribeiro (2004), o Raciocínio Lógico-Matemático e os programas EXCEL 2007 e AutoCAD 2009 que foram utilizados para auxiliar nos cálculos e nas simulações de campo. Os modelos encontrados demonstraram 100% de exatidão no que se refere ao dimensionamento e 100% de aplicabilidade em campo para biodigestores com proporções gás/fase líquida menores a 40%.</text>
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            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="143503">
                <text>2011</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="143504">
                <text>10.15628/holos.2011.269</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="143505">
                <text>Holos</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="143506">
                <text>Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="143507">
                <text>General Works</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="143508">
                <text>&lt;a href="http://www2.ifrn.edu.br/ojs/index.php/HOLOS/article/view/269" target="_blank" rel="noreferrer noopener"&gt;http://www2.ifrn.edu.br/ojs/index.php/HOLOS/article/view/269&lt;/a&gt;</text>
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  </item>
  <item itemId="4235" public="1" featured="0">
    <fileContainer>
      <file fileId="4235">
        <src>http://socictopen.socict.org/files/original/40617a5ba1d0f561e3278955f46fb194.pdf</src>
        <authentication>d39ca08fba16e16ccf39aba8023edf47</authentication>
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        <elementSet elementSetId="1">
          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38672">
                <text>Rapid Implementation and Innovative Applications of a Virtual Intensive Care Unit During the COVID-19 Pandemic: Case Study</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38673">
                <text>Dhala, Atiya, Sasangohar, Farzan, Kash, Bita, Ahmadi, Nima, Masud, Faisal</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38674">
                <text>BackgroundThe COVID-19 pandemic has necessitated a rapid increase of space in highly infectious disease intensive care units (ICUs). At Houston Methodist Hospital (HMH), a virtual intensive care unit (vICU) was used amid the COVID-19 outbreak.             ObjectiveThe aim of this paper was to detail the novel adaptations and rapid expansion of the vICU that were applied to achieve patient-centric solutions while protecting staff and patients’ families during the pandemic.             MethodsThe planned vICU implementation was redirected to meet the emerging needs of conversion of COVID-19 ICUs, including alterations to staged rollout timing, virtual and in-person staffing, and scope of application. With the majority of the hospital critical care physician workforce redirected to rapidly expanded COVID-19 ICUs, the non–COVID-19 ICUs were managed by cardiovascular surgeons, cardiologists, neurosurgeons, and acute care surgeons. HMH expanded the vICU program to fill the newly depleted critical care expertise in the non–COVID-19 units to provide urgent, emergent, and code blue support to all ICUs.             ResultsVirtual family visitation via the Consultant Bridge application, palliative care delivery, and specialist consultation for patients with COVID-19 exemplify the successful adaptation of the vICU implementation. Patients with COVID-19, who were isolated and separated from their families to prevent the spread of infection, were able to virtually see and hear their loved ones, which bolstered the mental and emotional status of those patients. Many families expressed gratitude for the ability to see and speak with their loved ones. The vICU also protected medical staff and specialists assigned to COVID-19 units, reducing exposure and conserving personal protective equipment.             ConclusionsTelecritical care has been established as an advantageous mechanism for the delivery of critical care expertise during the expedited rollout of the vICU at Houston Methodist Hospital. Overall responses from patients, families, and physicians are in favor of continued vICU care; however, further research is required to examine the impact of innovative applications of telecritical care in the treatment of critically ill patients.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38675">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="38676">
                <text>10.2196/20143</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="38677">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="45">
            <name>Publisher</name>
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                <text>Korean Society of Epidemiology</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Public aspects of medicine, Computer applications to medicine. Medical informatics</text>
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        <src>http://socictopen.socict.org/files/original/1db7e99d02e3536a254a3e6fd91ad564.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Modelling studies reveal the importance of the C-terminal inter motif loop of NSP1 as a promising target site for drug discovery and screening of potential phytochemicals to combat SARS-CoV-2.</text>
              </elementText>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="80416">
                <text>Dhamodharan Prabhu, Sundaraj Rajamanikandan, Muthusamy Sureshan, Jeyaraman Jeyakanthan, Kadhirvel Saraboji</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>COVID-19 pandemic causative SARS-CoV-2 coronavirus is still rapid in progression and transmission even after a year. Understanding the viral transmission and impeding the replication process within human cells are considered as the vital point to control and overcome COVID-19 infection. Non-structural Protein 1, one among the proteins initially produced upon viral entry into human cells, instantly binds with the human ribosome and inhibit the host translation process by preventing the mRNA attachment. However, the formation of NSP1 bound Ribosome complex does not affect the viral replication process. NSP1 plays an indispensable role in modulating the host gene expression and completely steals the host cellular machinery. The full-length structure of NSP1 is essential for the activity in the host cell and importantly the loop connecting N and C-terminal domains are reported to play a role in ribosome binding. Due to the unavailability of the experimentally determined full-length structure of NSP1, we have modelled the complete structure using comparative modelling and the stability and conformational behaviour of the modelled structure was evaluated through molecular dynamics simulation. Interestingly, the present study reveals the significance of the inter motif loop to serves as a potential binding site for drug discovery experiments. Further, we have screened the phytochemicals from medicinal plant sources since they were used for several hundred years that minimizes the traditional drug development time. Among the 5638 phytochemicals screened against the functionally associated binding site of NSP1, the best five phytochemicals shown high docking score of -9.63 to -8.75 kcal/mol were further evaluated through molecular dynamics simulations to understand the binding affinity and stability of the complex. Prime MM-GBSA analysis gave the relative binding free energies for the top five compounds (dihydromyricetin, 10-demethylcephaeline, dihydroquercetin, pseudolycorine and tricetin) in the range of -45.17 kcal/mol to -37.23 kcal/mol, indicating its binding efficacy in the predicted binding site of NSP1. The density functional theory calculations were performed for the selected five phytochemicals to determine the complex stability and chemical reactivity. Thus, the identified phytochemicals could further be used as effective anti-viral agents to overcome COVID-19 and as well as several other viral infections.</text>
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            <name>Date</name>
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                <text>2021</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="80419">
                <text>covid-19, virtual screening, Nonstructural protein 1, antiviral molecules, β-CoV</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="80420">
                <text>10.1016/j.jmgm.2021.107920</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="80421">
                <text>Journal of molecular graphics &amp; modelling</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
