http://socictopen.socict.org/files/original/15c13dd8da683144a450f7d2fa5540ec.pdf 478be619428405077ae0963579b8665e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Efficacy of decamethoxin against complex viruses regardless of their antigenic structure: prospects for use in modern viral diseases of the respiratory tract Creator An entity primarily responsible for making the resource M. I. Gumeniuk, G. L. Gumeniuk, S. G. Opimakh Description An account of the resource At the end of the 2019 and the beginning of 2020, an outbreak of viral pneumonia caused by the new coronavirus Coronavirus disease 2019 (Covid-19) began. From the history of outbreaks of severe acute respiratory syndrome in 2002–2003 and the Middle East respiratory syndrome in 2012, it is known that an effective and safe etiotropic treatment of coronavirus infection does not exist. Therefore, the actual challenge today is the fight against coronavirus infection. Potentially effective antiviral agents are antiseptics from the group of surfactants. In particular, decamethoxin, which has a pronounced bactericidal, fungicidal and antiprotistal effect, also has experimentally proven antiviral activity. In vitro, it was shown that decamethoxin exhibits a statistically significant virucidal effect influencing the extracellular virus with possible damage to the viral protease. In experiments on the tissue cultures and experimental animals, the ability of decamethoxin to inhibit the replication of influenza A and B viruses, herpes simplex virus by affecting the stage of virus penetration into the cell and viral nucleic acid replication has been proved. Another mechanism of decamethoxin action can be considered its effect on the early stages of the interaction of the virus with the host cell such as adsorption, penetration and deproteinization of the virus. The use of decamethoxin for the treatment of respiratory tract infections is pathogenetically justified due to the dosage form of a sterile solution for inhalation using a nebulizer — Decasan® single-dose containers. Decamethoxin is successfully used in the treatment of patients with infectious exacerbations of bronchial asthma and chronic bronchitis without negative impact on bronchial obstruction. The proven efficacy of decamethoxin as an effective agent against complex viruses regardless of their antigenic structure gives grounds for its practical use in respiratory tract infections, including coronavirus infection. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Coronavirus infection, Antiviral properties, decamethoxin, nebulizer therapy Identifier An unambiguous reference to the resource within a given context DOI: 10.22141/2312-413x.8.1.2020.196168 Source A related resource from which the described resource is derived Aktualʹnaâ Infektologiâ Publisher An entity responsible for making the resource available Publishing House Zaslavsky Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases Language A language of the resource EN, RU, UK