http://socictopen.socict.org/files/original/e96c3f0b8dce4f13bbe416a7eded649a.pdf 31634d91440c046942700563d9d6bd33 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cardiotoxicity of Immune Checkpoint Inhibitors. Creator An entity primarily responsible for making the resource Sourbha S Dani, Sarju Ganatra, Rushin P Patel, Rohan Parikh, Krishna S Gunturu, Rana Zouveenoor Tariq, Anju Nohria Description An account of the resource Immune checkpoint inhibitors (ICIs) have improved the survival of several cancers. However, they may cause a wide range of immune-related adverse events (irAEs). While most irAEs are manageable with temporary cessation of ICI and immunosuppression, cardiovascular toxicity can be associated with high rates of morbidity and mortality. As ICIs evolve to include high-risk patients with preexisting cardiovascular risk factors and disease, the risk and relevance of ICI-associated cardiotoxicity may be even higher. Several cardiovascular toxicities such as myocarditis, stress cardiomyopathy, and pericardial disease have been reported in association with ICIs. Recent findings also suggest an increased risk of atherosclerosis with ICI use. ICI-associated myocarditis usually occurs early after initiation and can be fulminant. A high index of suspicion is required for timely diagnosis. Prompt treatment with high-dose corticosteroids is shown to improve outcomes. Although the overall incidence is rare, ICI cardiotoxicity, particularly myocarditis, is associated with significant morbidity and mortality, making it a major therapy-limiting adverse event. Early recognition and prompt treatment with the cessation of ICI therapy and initiation of high-dose corticosteroids are crucial to improve outcomes. Cardio-oncologists will need to play an important role not just in the management of acute cardiotoxicity but also to reduce the risk of long-term sequelae. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource cancer, covid-19, Immunotherapy, myocarditis, immune checkpoint inhibitors, cardiotoxicity, pericarditis, stress cardiomyopathy Identifier An unambiguous reference to the resource within a given context 10.1007/s11912-021-01070-6 Source A related resource from which the described resource is derived Current oncology reports