http://socictopen.socict.org/files/original/07021f6a6bc384faad5d87765cb5bce2.pdf 5cfdea7ce852e997afd604b9f36d3fd7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Neutralizing Antibody Response and SARS Severity Creator An entity primarily responsible for making the resource Mei-Shang Ho, Wei-Ju Chen, Hour-Young Chen, Szu-Fong Lin, Min-Chin Wang, Jiali Di, Yen-Ta Lu, Ching-Lung Liu, Shan-Chwen Chang, Chung-Liang Chao, Chwan-Chuen King, Jeng-Min Chiou, Ih-Jen Su, Jyh-Yuan Yang Description An account of the resource Using the Taiwan nationwide laboratory-confirmed severe acute respiratory syndrome (SARS) database, we analyzed neutralizing antibody in relation to clinical outcomes. With a linear mixed model, neutralizing antibody titer was shown to peak between week 5 and week 8 after onset and to decline thereafter, with a half-life of 6.4 weeks. Patients with a longer illness showed a lower neutralizing antibody response than patients with a shorter illness duration (p = 0.008). When early responders were compared with most patients, who seroconverted on and after week 3 of illness, the small proportion (17.4%) of early responders (antibody detectable within 2 weeks) had a higher death rate (29.6% vs. 7.8%) (Fisher exact test, p = 0.004), had a shorter survival time of 60 years of age (Fisher exact test, p = 0.01). Our findings have implications for understanding the pathogenesis of SARS and for SARS vaccine research and development. Date A point or period of time associated with an event in the lifecycle of the resource 2005 Subject The topic of the resource SARS, neutralizing antibody, Antibody decay, Mortality, pathogenesis, ADE Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1111.040659 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN