Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection
real-time PCR, Prognosis, Blood, Viruses, coronavirus, Middle East respiratory syndrome
We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA was detected in blood from 33% of patients at initial diagnosis, and the detection preceded a worse clinical course.
Seung-Jun Lee, Moon-Woo Seong, Sung Sup Park, Jeong-Sun Yang, So-Yeon Kim, Sung Soon Kim, Ga-Yeon Kim, Hyeon-Gun Jee, Sun-Jae Park, Jeesoo Lee, Ran-hui Cha, Yu Mi Jung, Sung Im Cho, Man Jin Kim, Soo Hyun Seo, Yeonjae Kim, Hyoung-Shik Shin, Sook Young Cho
Centers for Disease Control and Prevention
Infectious and parasitic diseases, Medicine