An Overview of Novel Coronavirus SARS-Cov-2 Spanning around the Past, Present and Future Perspectives
Resilience, Pandemic, MERS-CoV, immunoinformatics, SARS-CoV-2, COVID-19
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a new enveloped RNA virus knownas Coronavirus (COVID-19) are most prevalent in humans and wild animals. All four species that isalpha, beta, delta and theta have been identified till date and are responsible for human disease;causing influenza like illness (ILI). This virus has similar lineage of Middle East Respiratory Syndromecoronavirus (MERS-CoV) and related Coronavirus (SARS-CoV). This outbreak initially presented aspneumonia-like illness in a group of people in Wuhan, China. The infection was said to be caused byseafood and unusual animals in the wholesale markets of this city. SARS-CoV-2 is highly infectious andhas resulted in a rapid pandemic. As of now it has spread to 197 countries with total no of cases inthe world being 3.76 million as of early march. The mortality till now is 7.11% . The cases have beenincreasing since its first discovery in China. In India also the number has been increased. Till nowIndia has total of 39,980 cases and mortality is attributed to be 3.26%. As per data from Ministry ofhealth and family welfare (MoHFW) death is more commonly seen in males with age >60years. Amongthese most of the deaths were related to other co-morbid conditions. This article will help the readerswith an overview of novel Coronavirus spanning around the clinical features, diagnostic modalities,treatment strategies and infection control measures. It will also help in raising awareness amonghealthcare workers regarding COVID-19 and aid in early recognition of these patients. Moreover, thisreview will also focus on the most recent information for the effective management, prevention, andtreatment of patients worldwide.
M.K. Verma, V. K. Srivastava, P Verma, A.N. Singh, J. Ahmad, Shadma Yaqoob, Areena H. Siddiqui, R. Harsvardhan
Journal of Pure and Applied Microbiology