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A Systematic, Unbiased Mapping of CD8+ and CD4+ T Cell Epitopes in Yellow Fever Vaccinees
Examining CD8+ and CD4+ T cell responses after primary Yellow Fever vaccination in a cohort of 210 volunteers, we have identified and tetramer-validated 92 CD8+ and 50 CD4+ T cell epitopes, many inducing strong and prevalent (i.e., immunodominant) T…
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Prioriteringsutfordringer i helse- og omsorgstjenesten i kommunene under covid-19-pandemien
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Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat
Martina Morokutti-Kurz,Christine Graf,Eva Prieschl-Grassauer Marinomed Biotechnologie GmbH, Vienna, Austria Abstract: Up to 80% of sore throats are caused by viruses. Several over the counter products are available which provide symptomatic, not…
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Synthesis, Molecular Properties Estimations, and Dual Dopamine D2 and D3 Receptor Activities of Benzothiazole-Based Ligands
Neurleptic drugs, e.g., aripiprazole, targeting the dopamine D2S and D3 receptors (D2SR and D3R) in the central nervous system are widely used in the treatment of several psychotic and neurodegenerative diseases. Therefore, a new series of…
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Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences.
Different vaccine approaches cope with HIV-1 diversity, ranging from centralized(1-4) to variability-encompassing(5-7) antigens. For all these strategies, a concern remains: how does HIV-1 diversity impact epitope recognition by the immune system? We…
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Recognition of HIV-1 peptides by host CTL is related to HIV-1 similarity to human proteins.
While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that contribute to immune recognition are not well understood. One hypothesis is that…
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Thirty Years of Research on Crown-of-Thorns Starfish (1986–2016): Scientific Advances and Emerging Opportunities
Research on the coral-eating crown-of-thorns starfish (CoTS) has waxed and waned over the last few decades, mostly in response to population outbreaks at specific locations. This review considers advances in our understanding of the biology and…
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Mucosal Immune Response to Feline Enteric Coronavirus Infection
Feline infectious peritonitis is a devastating, fatal disease of domestic cats caused by a pathogenic mutant virus derived from the ubiquitous feline enteric coronavirus (FECV). Infection by FECV is generally subclinical, and little is known about…
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ECOLOGÍA POBLACIONAL DE LA BABILLA (Caiman crocodilus fuscus) EN EL VALLE DEL RÍO MAGDALENA (CUNDINAMARCA, COLOMBIA)
Para proponer un plan de conservación de la babilla se estudiaron poblacionessilvestres y su hábitat en ambientes lóticos y lénticos en diez sitios en el valle delrío Magdalena, Cundinamarca. A partir de conteos nocturnos se registraron 464individuos…
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Urban landscape and public space as an expression of everyday life
Resumen Dado que el paisaje urbano es la expresión de todo lo que es posible percibir en los espacios públicos de la ciudad, el análisis de los atributos urbanos permite identificar patrones, secuencias y unidades del paisaje urbano que conducen a…
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