285 10 20655 https://socictopen.socict.org/files/original/f9590c30c64c45183cb2e75eedff19d5.pdf 6f4e5b77c732bec360d29f964e34daf4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource GERMINACIÓN DE ESTADOS DE RESISTENCIA DE DIATOMEAS Y DINOFLAGELADOS EN SEDIMENTOS MARINOS DE DOS ÁREAS DE SURGENCIA DE CHILE GERMINATION OF RESTING STAGES OF DIATOMS AND DINOFLAGELLATES IN MARINE SEDIMENTS FROM TWO UPWELLING AREAS OF CHILE Creator An entity primarily responsible for making the resource CARINA B LANGE, Gloria E Sánchez, Diana Sarno, Marina Montresor, Raffaele Siano Description An account of the resource Con el fin de evaluar la potencial germinación de los estados de resistencia de las diatomeas y dinofiagelados preservados en sedimentos superficiales, se cultivaron bajo condiciones de laboratorio sedimentos de las bahías de Mejillones (23° S) y Concepción (36° S), Chile: Ciclo L:0 12:12 h, intensidad de luz 140 umol m²s_1, temperatura ambiente y 35,4 unidades de salinidad. Las principales especies de diatomeas presentes en los sedimentos fueron Skeletonema japonicum y esporas de Chaetoceros. Los quistes de dinofiagelados estuvieron representados por Diplopsalis, Scrippsiella, Woloszynskia y las especies Protoperidinium avellanum y P. leonis. Después de 20 días de cultivo, se registró germinación y crecimiento de S. japonicum y de varias especies de Chaetoceros, sin embargo su abundancia fue baja. Las diatomeas con crecimiento abundante fueron Stauroneis legleri, Pseudostaurosira trainorii, Pseudostaurosira sp.l, Pseudostaurosira sp. 2 y Navícula pseudoreinhardtii. El dinoflagelado Woloszynskia sp. también germinó y creció abundantemente. Este trabajo incluye una breve descripción de las especies cultivadas y algunos aspectos de su ecología. Se discuten las posibles causas de la pobre germinación de las diatomeas planctónicas, siendo la baja concentración de oxígeno disuelto en las aguas de fondo uno de los principales factores que presumiblemente afectaron la sobrevivencia de las esporas de resistencia.With the aim to assess germination of diatom and dinofiagellates resting spores we cultured under laboratory conditions surface sediments collected in the Mejillones Bay (23° S) and off Concepción (36° S), Chile. These sediments were cultured in the laboratory with a 12:12 h L/D cycle, light intensity of 140 umol m² s'¹, at room temperature, and with a salinity of 35.4 units. The main diatom species in the sediments were Skeletonema japonicum and Chaetoceros spores. Dinofiagellate cysts were represented by the genera Diplopsalis, Scrippsiella, and Woloszynskia and the species Protoperidinium avellanum and P. leonis. After 20 days of culturing, germination and growth was recorded for S. japonicum and several of the Chaetoceros species, although their abundance was low. The diatoms with abundant growth were Stauroneis legleri, Pseudostaurosira trainorii, Pseudostaurosira sp.l, Pseudostaurosira sp. 2, and Navícula pseudoreinhardtii. The dinofiagellate Woloszynskia sp. also germinated and grew abundantly in the culture. This study includes a brief description of the cultured species and some aspects of their ecology. In addition, we discuss the possible causes for low levels of germination in planktonic diatoms, finding low dissolved oxygen concentrations in the bottom waters to be one of the main factors that presumably affected the survival of resting spores in the sediment. Date A point or period of time associated with an event in the lifecycle of the resource 2009 Subject The topic of the resource Chile, Diatomeas, Diatoms, cultivos, cultures, dinoflagelados, dinoflagellates, estados de resistencia, resting stages, sedimentos, sediments Source A related resource from which the described resource is derived Gayana: Botanica Publisher An entity responsible for making the resource available Universidad de Concepción Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Botany Relation A related resource <a href="http://www.scielo.cl/scielo.php?script=sci_arttext&amp;pid=S0717-66432009000200009" target="_blank" rel="noreferrer noopener">http://www.scielo.cl/scielo.php?script=sci_arttext&amp;pid=S0717-66432009000200009</a> https://socictopen.socict.org/files/original/a6d1ed7fe202b25bdcea0ed543ddba79.pdf 66287c5eada1033138229450a0a06687 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Distribuição espaço-temporal e sucesso reprodutivo de Eretmochelys imbricata nas praias do Ipojuca, Pernambuco, Brasil Spatio-temporal distribution and reproductive success of Eretmochelys imbricata on the beaches of Ipojuca, Pernambuco, Brazil Creator An entity primarily responsible for making the resource Carina C. de M. Moura, Elisângela da S. Guimarães, Geraldo J. B. de Moura, Getúlio J. A. do Amaral, Arley C. da Silva Description An account of the resource Este estudo objetivou verificar a distribuição temporal e espacial de Eretmochelys imbricata (Linnaeus, 1766) e aspectos de sua biologia reprodutiva, tais como tempo de incubação, sucesso reprodutivo, biometria das fêmeas, número de ninhos e fecundidade. Os dados foram coletados de 2007 a 2010 nas praias de Muro Alto, Cupe, Merepe, Porto de Galinhas e Maracaípe, todas elas localizadas no município do Ipojuca, estado de Pernambuco, Brasil. Foram analisados comparativamente parâmetros relativos à biologia reprodutiva e áreas de nidificação da espécie. Eretmochelys imbricata foi registrada nidificando entre os meses de outubro a maio, totalizando 350 ninhos monitorados em três temporadas. Os picos de desova ocorreram de janeiro a março, revelando um padrão sazonal das desovas. Houve diferença significativa entre o número de ninhos nas temporadas. A praia de Merepe apresentou uma ocorrência elevada de ninhos (46 ninhos/km) em relação às demais praias monitoradas. Quanto aos aspectos da biologia reprodutiva, o sucesso reprodutivo foi 65,6%, e o intervalo do tempo de incubação de 54 a 56 dias. As medidas biométricas foram coletadas de 59 espécimes, e apresentaram média de 92,5 cm ± 4,5 para o comprimento curvilíneo da carapaça e de 83,4 cm ± 5 para a largura curvilínea da carapaça. Os resultados podem ser utilizados para subsidiar planos de conservação e demonstram que as praias registradas neste estudo têm relevância como áreas de nidificação para E. imbricata.This study aimed to verify the spatio-temporal distribution of Eretmochelys imbricata (Linnaeus, 1766) and aspects of its reproductive biology, such as incubation time, reproductive success, biometric measurements of females, number of nests and fecundity. Data were collected during 2007 to 2010, on the beaches of Muro Alto, Cupe, Merepe, Porto de Galinhas, and Maracaípe, all of them located in the city of Ipojuca, state of Pernambuco, Brazil. Parameters relating to reproductive biology and nesting areas of the species were comparatively analyzed. Eretmochelys imbricata was recorded nesting between October and May, when 350 nests were monitored through three seasons. The spawning peak happened from January to March, also revealing a seasonal pattern. The number of nests differed significantly between seasons. The Merepe beach presented an elevated occurrence of nests (46 nests/km) if compared to the other monitored beaches. On the aspects of reproductive biology, the reproductive success was 65,6% and the incubation time interval ranged from 54 to 56 days. Biometric measurements were collected from 59 specimens, resulting in an average of 92,5 cm ± 4,5 for the curved carapace length, and of 83,4 cm ± 5 for the curved carapace width. The results can be used for subsidize conservation plans and demonstrate that the beaches recorded in this study are relevant as nesting areas for E. imbricata. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource Hawksbill turtle, Reproduction, Reprodução, Tartaruga-de-pente, Testudine, ecology, ecología, seasons, temporadas Source A related resource from which the described resource is derived Iheringia: Série Zoologia Publisher An entity responsible for making the resource available Fundação Zoobotânica do Rio Grande do Sul Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Zoology Relation A related resource <a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0073-47212012000300002" target="_blank" rel="noreferrer noopener">http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0073-47212012000300002</a> https://socictopen.socict.org/files/original/3ce662c1c53ab2356f1ae9f7eec9fb70.pdf 66287c5eada1033138229450a0a06687 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Distribuição espaço-temporal e sucesso reprodutivo de Eretmochelys imbricata nas praias do Ipojuca, Pernambuco, Brasil Creator An entity primarily responsible for making the resource Carina C. de M. Moura, Elisângela da S. Guimarães, Geraldo J. B. de Moura, Getúlio J. A. do Amaral, Arley C. da Silva Description An account of the resource Este estudo objetivou verificar a distribuição temporal e espacial de Eretmochelys imbricata (Linnaeus, 1766) e aspectos de sua biologia reprodutiva, tais como tempo de incubação, sucesso reprodutivo, biometria das fêmeas, número de ninhos e fecundidade. Os dados foram coletados de 2007 a 2010 nas praias de Muro Alto, Cupe, Merepe, Porto de Galinhas e Maracaípe, todas elas localizadas no município do Ipojuca, estado de Pernambuco, Brasil. Foram analisados comparativamente parâmetros relativos à biologia reprodutiva e áreas de nidificação da espécie. Eretmochelys imbricata foi registrada nidificando entre os meses de outubro a maio, totalizando 350 ninhos monitorados em três temporadas. Os picos de desova ocorreram de janeiro a março, revelando um padrão sazonal das desovas. Houve diferença significativa entre o número de ninhos nas temporadas. A praia de Merepe apresentou uma ocorrência elevada de ninhos (46 ninhos/km) em relação às demais praias monitoradas. Quanto aos aspectos da biologia reprodutiva, o sucesso reprodutivo foi 65,6%, e o intervalo do tempo de incubação de 54 a 56 dias. As medidas biométricas foram coletadas de 59 espécimes, e apresentaram média de 92,5 cm ± 4,5 para o comprimento curvilíneo da carapaça e de 83,4 cm ± 5 para a largura curvilínea da carapaça. Os resultados podem ser utilizados para subsidiar planos de conservação e demonstram que as praias registradas neste estudo têm relevância como áreas de nidificação para E. imbricata. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource Reprodução, Tartaruga-de-pente, Testudine, ecología, temporadas Source A related resource from which the described resource is derived Iheringia: Série Zoologia Publisher An entity responsible for making the resource available Fundação Zoobotânica do Rio Grande do Sul Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Zoology Relation A related resource <a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0073-47212012000300002&amp;lng=en&amp;tlng=en" target="_blank" rel="noreferrer noopener">http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0073-47212012000300002&amp;lng=en&amp;tlng=en</a> https://socictopen.socict.org/files/original/7bc6ecf26061b47660737344213c628f.pdf 935dd8f8f81782bd2c258449c25f4f3b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Jumping spider (Araneae: Salticidae) diversity in the understory of the Argentinian Atlantic Forest Creator An entity primarily responsible for making the resource Carina I. Argañaraz, Gonzalo D. Rubio, Raquel M. Gleiser Description An account of the resource The Atlantic Forest is one of the key biodiversity hotspots in the world. Its understory can be dominated by species such as the native bamboo Chusquea ramosissima (tacuarembó), which can be an aggressive gap colonizer and change biotic and abiotic conditions compared to mature forest. A strong association has been observed between Salticidae spiders and microhabitat type, frequently linked to host plant structure. Since little is known about the diversity of spiders in tree-fall gaps of the Atlantic Forest, the differences in the Salticidae assemblages between three habitats –the understory of typical forest, Bamboo gaps (dominated by tacuarembó) and restoration areas (tacuarembó removal)– were explored in the southern tip of the Atlantic Forest, Upper Parana Atlantic Forest ecoregion in Misiones province, Argentina. A total of 515 jumping spiders (32 species; 106 adults) were collected. Differences in species composition were detected between habitats, where Forest understory and Bamboo gaps differ in almost 50% of the species. Bamboo gaps had the highest number of exclusive species, but the three habitats did not differ in their average taxonomic diversity indices. In addition, richness was higher in Bamboo gaps compared to Forest understory, which may reflect higher niche diversity in the former habitat. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Bamboo gaps, Chusquea ramosissima, Salticid, South America, community, rainforest Identifier An unambiguous reference to the resource within a given context 10.15446/caldasia.v39n1.60527 Source A related resource from which the described resource is derived Caldasia Publisher An entity responsible for making the resource available Universidad Nacional de Colombia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Botany, Zoology Relation A related resource <a href="https://revistas.unal.edu.co/index.php/cal/article/view/60527" target="_blank" rel="noreferrer noopener">https://revistas.unal.edu.co/index.php/cal/article/view/60527</a> https://socictopen.socict.org/files/original/7093a57c6af0843c851f78394d7a39dc.pdf faf2c8a0990880791d9680276d2a936f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Ecuadorian Political System: Tension in the context of the COVID 19 (March-May 2020) Creator An entity primarily responsible for making the resource Carina V. Ganuza Description An account of the resource The Ecuadorian political system represented by President Lenin Moreno has caused an atmosphere of constant tension in the face of the spread of COVID 19, leading to a setting of greater disturbance as the health crisis situation, that was used to apply neoliberal measuresthat had been suspended in October 2019, in the setting of massive protests and discontent. This work is a case study that analyzes the decisions made by the Moreno administration in the face of the pandemic in the temporary cutback that took place during the months of March and May of 2020, a clear move to take advantage of the health crisis situation, and in order to complete its decisions regarding  austerity and budget cutbacks. It is, thus, inferred that there is a loss of the sense of protection of life as a primary constitutional right. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, health, neoliberalism, political system Identifier An unambiguous reference to the resource within a given context 10.47577/tssj.v11i1.1585 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General) https://socictopen.socict.org/files/original/d99c87232d0234620a19c73c3d55c80b.pdf da430c9b68a82d5ab71d72979d1b998a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Fine Tuning the Cytokine Storm by IFN and IL-10 Following Neurotropic Coronavirus Encephalomyelitis Creator An entity primarily responsible for making the resource Carine Savarin, Cornelia C. Bergmann Description An account of the resource The central nervous system (CNS) is vulnerable to several viral infections including herpes viruses, arboviruses and HIV to name a few. While a rapid and effective immune response is essential to limit viral spread and mortality, this anti-viral response needs to be tightly regulated in order to limit immune mediated tissue damage. This balance between effective virus control with limited pathology is especially important due to the highly specialized functions and limited regenerative capacity of neurons, which can be targets of direct virus cytolysis or bystander damage. CNS infection with the neurotropic strain of mouse hepatitis virus (MHV) induces an acute encephalomyelitis associated with focal areas of demyelination, which is sustained during viral persistence. Both innate and adaptive immune cells work in coordination to control virus replication. While type I interferons are essential to limit virus spread associated with early mortality, perforin, and interferon-γ promote further virus clearance in astrocytes/microglia and oligodendrocytes, respectively. Effective control of virus replication is nonetheless associated with tissue damage, characterized by demyelinating lesions. Interestingly, the anti-inflammatory cytokine IL-10 limits expansion of tissue lesions during chronic infection without affecting viral persistence. Thus, effective coordination of pro- and anti-inflammatory cytokines is essential during MHV induced encephalomyelitis in order to protect the host against viral infection at a limited cost. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource central nervous system, Viral infection, JHMV, IFN-αβ, IFN-γ, IL-10 Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fimmu.2018.03022 Source A related resource from which the described resource is derived Frontiers in Immunology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy Language A language of the resource EN https://socictopen.socict.org/files/original/158e5e4e4dcf2c6e6da85d29db5b79c4.pdf dbbf08778dd987c20be95347b9786caf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Differential regulation of self-reactive CD4 T cells in cervical lymph nodes and central nervous system during viral encephalomyelitis Creator An entity primarily responsible for making the resource Carine Savarin, Cornelia C. Bergmann, David R. Hinton, Stephen A. Stohlman Description An account of the resource Viral infections have long been implicated as triggers of autoimmune diseases, including Multiple Sclerosis (MS), a central nervous system (CNS) inflammatory demyelinating disorder. Epitope spreading, molecular mimicry, cryptic antigen and bystander activation have been implicated as mechanisms responsible for activating self-reactive (SR) immune cells, ultimately leading to organ-specific autoimmune disease. Taking advantage of coronavirus JHM strain of mouse hepatitis virus (JHMV) induced demyelination, this study demonstrates that the host also mounts counteractive measures to specifically limit expansion of endogenous SR T cells. In this model, immune mediated demyelination is associated with induction of SR T cells after viral control. However, their decline during persisting infection, despite ongoing demyelination, suggests an active control mechanism.Antigen-specific IL-10 secreting CD4+ T cells (Tr1) and Foxp3+ regulatory T cells (Tregs), both known to control autoimmunity and induced following JHMV infection, were assessed for their relative in vivo suppressive function of SR T cells. Ablation of Foxp3+ Tregs in chronically infected DEREG mice significantly increased SR CD4+ T cells within cervical lymph nodes (CLN), albeit without affecting their numbers or activation within the CNS compared to controls. In contrast, infected IL-27 receptor deficient (IL-27R-/-) mice, characterized by a drastic reduction of Tr1 cells, revealed that SR CD4+ T cells in CLN remained unchanged, but were specifically increased within the CNS. These results suggest that distinct regulatory T cell subsets limit SR T cells in the draining lymph nodes and CNS to maximize suppression of SR T cell mediated autoimmune pathology. The JHMV model is thus valuable to decipher tissue specific mechanisms preventing autoimmunity. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource autoimmunity, central nervous system, CD4+ T cells, Viral infection, Tr1 cells, FOXP3+ regulatory T cells Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fimmu.2016.00370 Source A related resource from which the described resource is derived Frontiers in Immunology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy Language A language of the resource EN https://socictopen.socict.org/files/original/e97bb6406acf96a75b53c3e02a363e3f.pdf cf2247d928e680d134240fb965e71c22 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Distinct Gene Profiles of Bone Marrow-Derived Macrophages and Microglia During Neurotropic Coronavirus-Induced Demyelination Creator An entity primarily responsible for making the resource Carine Savarin, Ranjan Dutta, Cornelia C. Bergmann Description An account of the resource Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal loss. Demyelinating lesions are associated with infiltrating T lymphocytes, bone marrow-derived macrophages (BMDM), and activated resident microglia. Tissue damage is thought to be mediated by T cell produced cytokines and chemokines, which activate microglia and/or BMDM to both strip myelin and produce toxic factors, ultimately damaging axons and promoting disability. However, the relative contributions of BMDM and microglia to demyelinating pathology are unclear, as their identification in MS tissue is difficult due to similar morphology and indistinguishable surface markers when activated. The CD4 T cell-induced autoimmune murine model of MS, experimental autoimmune encephalitis (EAE), in which BMDM are essential for demyelination, has revealed pathogenic and repair-promoting phenotypes associated with BMDM and microglia, respectively. Using a murine model of demyelination induced by a gliatropic coronavirus, in which BMDM are redundant for demyelination, we herein characterize gene expression profiles of BMDM versus microglia associated with demyelination. While gene expression in CNS infiltrating BMDM was upregulated early following infection and subsequently sustained, microglia expressed a more dynamic gene profile with extensive mRNA upregulation coinciding with peak demyelination after viral control. This delayed microglia response comprised a highly pro-inflammatory and phagocytic profile. Furthermore, while BMDM exhibited a mixed phenotype of M1 and M2 markers, microglia repressed the vast majority of M2-markers. Overall, these data support a pro-inflammatory and pathogenic role of microglia temporally remote from viral control, whereas BMDM retained their gene expression profile independent of the changing environment. As demyelination is caused by multifactorial insults, our results highlight the plasticity of microglia in responding to distinct inflammatory settings, which may be relevant for MS pathogenesis. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource macrophages, Microglia, central nervous system, demyelination, viral encephalomyelitis Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fimmu.2018.01325 Source A related resource from which the described resource is derived Frontiers in Immunology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy Language A language of the resource EN https://socictopen.socict.org/files/original/f27af24c78d34fb2d10fa9a15ba9ff9b.pdf 87f92d3e2810ceecc060e7598b95d1a0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Citizens Facing COVID-19: Inequalities and Vulnerabilities of the Working Class The World Before COVID-19 Creator An entity primarily responsible for making the resource Carl E. D. Pierre Description An account of the resource This paper relies on recent studies to describe the hardship of working-class people during the COVID-19 crisis, their vulnerabilities, and how social inequalities play a significant role in their exposure to the virus and its more severe and potentially deadly expressions. We show how existing inequalities before the pandemic, along with public policy, create the sanitary, financial, and economic disaster we are facing now. It is crucial to understand the pandemic's impacts on blue-collar workers and state-sponsored measures to fight against it. This essay also shows the need for further research on working-class issues such as their resilience to financial and sanitary hardship. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, vulnerability, inequality, Working class, financial resilience Identifier An unambiguous reference to the resource within a given context 10.46324/PMP2003270 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social history and conditions. Social problems. Social reform https://socictopen.socict.org/files/original/5a02f0c7f99662d7369ce223a4996ea3.pdf 4897a08f1f07dd50f1f09a1d55e4df83 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19: Neurological Considerations in Neonates and Children Creator An entity primarily responsible for making the resource Carl E. Stafstrom, Lauren L. Jantzie Description An account of the resource The ongoing worldwide pandemic of the novel human coronavirus SARS-CoV-2 and the ensuing disease, COVID-19, has presented enormous and unprecedented challenges for all medical specialists. However, to date, children, especially neonates, have been relatively spared from the devastating consequences of this infection. Neurologic involvement is being increasingly recognized among adults with COVID-19, who can develop sensory deficits in smell and taste, delirium, encephalopathy, headaches, strokes, and peripheral nervous system disorders. Among neonates and children, COVID-19-associated neurological manifestations have been relatively rare, yet reports involving neurologic dysfunction in this age range are increasing. As discussed in this review, pediatric neurologists and other pediatric specialists should be alert to potential neurological involvement by this virus, which might have neuroinvasive capability and carry long-term neuropsychiatric and medical consequences. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, covid-19, SARS-CoV-2, neurological, Neonate, Brain Identifier An unambiguous reference to the resource within a given context 10.3390/children7090133 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pediatrics