295 10 20655 https://socictopen.socict.org/files/original/9309c0bdec6e002f0fb34ae8a3e19d6c.pdf 3b7543057f91fba45cbfae0fc791476e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Brief review of coronavirus for healthcare professionals February 10, 2020 Creator An entity primarily responsible for making the resource Robbins RA, Klotz SA Description An account of the resource No abstract available. Article truncated after 150 words. The epidemic of coronavirus (2019-nCoV) near Wuhan City and the surrounding Hubei Province in China has received extensive news coverage. Some have predicted the virus will cause a worldwide pandemic (1). The CDC has an extensive website discussing over numerous pages whom to suspect, how to diagnose and how to treat 2019-nCoV. 2019-nCoV represents the most recent of the severe coronaviral infections. Severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) are also caused by coronaviruses that have jumped from animals to humans like 2019-nCoV. It should be remembered that there are only 12 confirmed cases of 2019-nCoV in the US and the mortality rate appears to be only about 3% which is lower than SARS or MERS (2,3). This could be offset by a greater infectiousness of 2019-nCoV resulting in more aggregate infectious, and hence, deaths. Anyone with a fever who has recently visited the epidemic area … Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource diagnosis, treatment, China, Mortality, symptoms, coronavirus, Wuhan, Hubei, 2019ncov Identifier An unambiguous reference to the resource within a given context DOI: 10.13175/swjpcc011-20 Source A related resource from which the described resource is derived Southwest Journal of Pulmonary and Critical Care Publisher An entity responsible for making the resource available Arizona Thoracic Society Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medical emergencies. Critical care. Intensive care. First aid, General works https://socictopen.socict.org/files/original/7f299288145283bac237fdfae52f2293.pdf e652af81b6b83b9bffbb1020357a12f9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Brief Summary of Potential SARS-CoV-2 Prophylactic and Treatment Drugs in the Emergency Department Creator An entity primarily responsible for making the resource Jeanne Noble, Zlatan Coralic, Cortlyn Brown Description An account of the resource As of March 30 th, 2020 there were 161,807 total cases and 2,953 total deaths of SARS-CoV-2 in the United States, with the number of cases expected to rise. Other than supportive care, there are no SARS-CoV-2 specific treatments available for patients discharged from the emergency department (ED) or those admitted to the hospital. In addition, there are no vaccines available to protect our at-risk healthcare workers. The National Institutes of Health is conducting a Phase 1 clinical trial to evaluate for a potential vaccine and the recipients have started to receive the investigational vaccine. 2 We present a brief overview of the potential prophylactic and treatment agents under investigation, some which could be initiated in the ED if proven effective. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.5811/westjem.2020.3.47328 Source A related resource from which the described resource is derived Western Journal of Emergency Medicine Publisher An entity responsible for making the resource available eScholarship Publishing, University of California Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Medical emergencies. Critical care. Intensive care. First aid https://socictopen.socict.org/files/original/8fa6a90fc5e85c26a9a3a0378f007df6.pdf c4603a68ef62b326bc5d1d6aa572d47c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Brincadeiras de rua, convivência urbana e ecologia dos saberes Creator An entity primarily responsible for making the resource ÁLAMO PIMENTEL Description An account of the resource Este artículo es el resultado de un estudio sobre la contribución de los juegos de la calle en la creación de procesos de convivencia urbana y en la diversificación de prácticas y saberes inherentes a las culturas populares que atraviesan lo cotidiano de las ciudades brasileñas. El texto se desarrolla a partir del análisis de documentos basados en los informes presentados por estudiantes de pedagogía de una institución de enseñanza superior del estado de Bahía. Los informes descriptivos analizados son el resultado de un proyecto didáctico de observación desde el punto de vista de los niños sobre la convivencia urbana. La base teórica del trabajo se inspira en las epistemologías del Sul según la propuesta de Boaventura de Sousa Santos (2008), sobre todo en lo referido a la comprensión de las ecologías de los saberes. A partir de los cuadros sinópticos presentados a lo largo del texto se expone una visión panorámica de los juegos de la calle en diferentes barrios de Salvador y sus implicaciones en la sustentabilidad de las culturas populares en los escenarios urbanos contemporáneos. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Source A related resource from which the described resource is derived Revista Brasileira de Educação Publisher An entity responsible for making the resource available Associacao Nacional de Pós-Graduação e Pesquisa em Educação Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Education Relation A related resource <a href="http://www.redalyc.org/articulo.oa?id=27540282007" target="_blank" rel="noreferrer noopener">http://www.redalyc.org/articulo.oa?id=27540282007</a> https://socictopen.socict.org/files/original/b21f8de73e5c7e2d24b031e075a30e95.pdf 63074faf97427df24bd2ad9d1bf07652 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bringing small farmers closer to data access and use: building bridges between their needs and ICT Creator An entity primarily responsible for making the resource Jacquelin Teresa Camperos Reyes, Fábio Mosso Moreira Description An account of the resource The editorial comments on the contribution of research results to the study about process of access and use of data by the small farmers. Relationships are established between the articles published in volume 6 (number 1) of RECoDAF, which present perceptions obtained in case studies conducted with producers and disseminate proposals for the development and application of technological resources, demonstrating possibilities of meeting the information needs of this segment from a new information technologies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Acesso a dados, Necessidades informacionais, Tecnologia da informação e comunicação Source A related resource from which the described resource is derived Revista Eletrônica Competências Digitais para Agricultura Familiar Publisher An entity responsible for making the resource available Universidade Estadual Paulista Júlio de Mesquita Filho Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture (General) Relation A related resource <a href="http://codaf.tupa.unesp.br:8082/index.php/recodaf/article/view/122" target="_blank" rel="noreferrer noopener">http://codaf.tupa.unesp.br:8082/index.php/recodaf/article/view/122</a> https://socictopen.socict.org/files/original/8b8387fcd93642d81f9013f5fc153897.pdf 1a5d3ed56ec32e35ef1f143304ea9315 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Broad respiratory testing to identify SARS-CoV-2 viral co-circulation and inform diagnostic stewardship in the COVID-19 pandemic Creator An entity primarily responsible for making the resource Natalie C. Marshall, Ruwandi M. Kariyawasam, Nathan Zelyas, Jamil N. Kanji, Mathew A. Diggle Description An account of the resource Abstract Background SARS-CoV-2 infection can present with a broad clinical differential that includes many other respiratory viruses; therefore, accurate tests are crucial to distinguish true COVID-19 cases from pathogens that do not require urgent public health interventions. Co-circulation of other respiratory viruses is largely unknown during the COVID-19 pandemic but would inform strategies to rapidly and accurately test patients with respiratory symptoms. Methods This study retrospectively examined 298,415 respiratory specimens collected from symptomatic patients for SARS-CoV-2 testing in the three months since COVID-19 was initially documented in the province of Alberta, Canada (March-May, 2020). By focusing on 52,285 specimens that were also tested with the Luminex Respiratory Pathogen Panel for 17 other pathogens, this study examines the prevalence of 18 potentially co-circulating pathogens and their relative rates in prior years versus since COVID-19 emerged, including four endemic coronaviruses. Results SARS-CoV-2 was identified in 2.2% of all specimens. Parallel broad multiplex testing detected additional pathogens in only 3.4% of these SARS-CoV-2-positive specimens: significantly less than in SARS-CoV-2-negative specimens (p  Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, human, SARS-CoV-2, Coronavirus OC43, coronavirus NL63, Endemic coronaviruses, Coronavirus 229E Identifier An unambiguous reference to the resource within a given context 10.1186/s12985-021-01545-9 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases https://socictopen.socict.org/files/original/deec8b13afd1b3378dbce5763190f7ec.pdf c985bc106207ca3daf03b72262adfb4e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Broad-Spectrum Antiviral Strategies and Nucleoside Analogues Creator An entity primarily responsible for making the resource Robert J. Geraghty, Matthew T. Aliota, Laurent F. Bonnac Description An account of the resource The emergence or re-emergence of viruses with epidemic and/or pandemic potential, such as Ebola, Zika, Middle East Respiratory Syndrome (MERS-CoV), Severe Acute Respiratory Syndrome Coronavirus 1 and 2 (SARS and SARS-CoV-2) viruses, or new strains of influenza represents significant human health threats due to the absence of available treatments. Vaccines represent a key answer to control these viruses. However, in the case of a public health emergency, vaccine development, safety, and partial efficacy concerns may hinder their prompt deployment. Thus, developing broad-spectrum antiviral molecules for a fast response is essential to face an outbreak crisis as well as for bioweapon countermeasures. So far, broad-spectrum antivirals include two main categories: the family of drugs targeting the host-cell machinery essential for virus infection and replication, and the family of drugs directly targeting viruses. Among the molecules directly targeting viruses, nucleoside analogues form an essential class of broad-spectrum antiviral drugs. In this review, we will discuss the interest for broad-spectrum antiviral strategies and their limitations, with an emphasis on virus-targeted, broad-spectrum, antiviral nucleoside analogues and their mechanisms of action. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource broad-spectrum antivirals, nucleoside analogues, lethal mutagenesis, chain terminator Identifier An unambiguous reference to the resource within a given context 10.3390/v13040667 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://socictopen.socict.org/files/original/e288187522d6ba800c5f6c14a5c8691f.pdf 7b45cde64f6059476bde6bfd44e410c3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Creator An entity primarily responsible for making the resource Kelvin Kai-Wang To, Kwok-yung Yuen, Fei-fei Yin, Jian-Piao Cai, Ivan Fan-Ngai Hung, Kenn Ka-Heng Chik, Zi-Wei Ye, Kai-ming Tang, Jianli Cao, Chris Chun-Yiu Chan, Ronghui Liang, Jasper Fuk-Woo Chan, Dong-Yan Jin, Shuofeng Yuan, Jessica Oi-Ling Tsang, Hin Chu Description An account of the resource The ongoing Coronavirus Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signals an urgent need for an expansion in treatment options. In this study, we investigated the anti-SARS-CoV-2 activities of 22 antiviral agents with known broad-spectrum antiviral activities against coronaviruses and/or other viruses. They were first evaluated in our primary screening in VeroE6 cells and then the most potent anti-SARS-CoV-2 antiviral agents were further evaluated using viral antigen expression, viral load reduction, and plaque reduction assays. In addition to remdesivir, lopinavir, and chloroquine, our primary screening additionally identified types I and II recombinant interferons, 25-hydroxycholesterol, and AM580 as the most potent anti-SARS-CoV-2 agents among the 22 antiviral agents. Betaferon (interferon-β1b) exhibited the most potent anti-SARS-CoV-2 activity in viral antigen expression, viral load reduction, and plaque reduction assays among the recombinant interferons. The lipogenesis modulators 25-hydroxycholesterol and AM580 exhibited EC50 at low micromolar levels and selectivity indices of >10.0. Combinational use of these host-based antiviral agents with virus-based antivirals to target different processes of the SARS-CoV-2 replication cycle should be evaluated in animal models and/or clinical trials. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource treatment, coronavirus, interferon, 25-hydroxycholesterol, COVID-19, AM580 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12060628 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG https://socictopen.socict.org/files/original/ca1951e89566ed76b64ca0cb8417d72d.pdf a73556ee12cea0e067b63d5ce69ab230 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Broccoli yield in response to top-dressing fertilization with green manure and biofertilizer Creator An entity primarily responsible for making the resource Ricardo Henrique Silva Santos, Gilberto Bernardo de Freitas, Márcio Sousa Rocha, Letícia Monteiro da Silva Freitas, Leandro de Almeida Resende Description An account of the resource The objective of this work was to evaluate the productive performance of broccoli under different top-dressing organic fertilizations. The experiment was conducted under protected cultivation, in a completely randomized design with four replications, with two plants per experimental unit. Broccoli seedlings were produced in a commercial substrate in styrofoam trays. The seedlings were transplanted to plastic pots containing 10.0 L of substrate made up of subsoil and organic compost at the ratio of 3:1 (v/v), respectively, which is equivalent to about 20.0 t ha-1 of organic compost at planting. After seedling establishment, the top-dressing fertilization treatments were applied: gliricidia biomass associated or not with liquid biofertilizer of cattle manure to the soil and bokashi. Two control treatments were established: one with mineral fertilization recommended for the crop and the other without top-dressing fertilization. The broccoli production was evaluated (commercial standard). Plants that received mineral fertilizer were more productive, however, they were not significantly different (p>0.05), by Dunnet test, from the plants fertilized with 2.5 t ha-1 gliricidiabiomass (dry mass) associated with liquid biofertilizer (2.0 L m-2) applied to soil. Top-dressing fertilizations with only gliricidia, at 2.5 and 5.0 t ha-1 of biomass (dry mass), resulted in no significant increase in production of broccoli inflorescence. The use of bokashi in addition to gliricidia biomass and liquid biofertilizer reduced the efficiency of the fertilization compared with plants that received only gliricidia and liquid biofertilizer. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Subject The topic of the resource Brassica oleracea L. var. italica, Gliricidia sepium (Jacq.), adubação orgânica, biofertilizante, olericultura orgânica Identifier An unambiguous reference to the resource within a given context 10.1590/S0034-737X2011000500016 Source A related resource from which the described resource is derived Revista Ceres Publisher An entity responsible for making the resource available Universidade Federal de Viçosa Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture (General), Biotechnology Relation A related resource <a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0034-737X2011000500016&amp;lng=en&amp;tlng=en" target="_blank" rel="noreferrer noopener">http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0034-737X2011000500016&amp;lng=en&amp;tlng=en</a> https://socictopen.socict.org/files/original/70dfa04acc6456a96c568411ecc7af49.pdf a356b63d272f7bc105d9f81c8de88df6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization Creator An entity primarily responsible for making the resource Carl G. de Boer, Aviv Regev Description An account of the resource Abstract Background Variation in chromatin organization across single cells can help shed important light on the mechanisms controlling gene expression, but scale, noise, and sparsity pose significant challenges for interpretation of single cell chromatin data. Here, we develop BROCKMAN (Brockman Representation Of Chromatin by K-mers in Mark-Associated Nucleotides), an approach to infer variation in transcription factor (TF) activity across samples through unsupervised analysis of the variation in DNA sequences associated with an epigenomic mark. Results BROCKMAN represents each sample as a vector of epigenomic-mark-associated DNA word frequencies, and decomposes the resulting matrix to find hidden structure in the data, followed by unsupervised grouping of samples and identification of the TFs that distinguish groups. Applied to single cell ATAC-seq, BROCKMAN readily distinguished cell types, treatments, batch effects, experimental artifacts, and cycling cells. We show that each variable component in the k-mer landscape reflects a set of co-varying TFs, which are often known to physically interact. For example, in K562 cells, AP-1 TFs were central determinant of variability in chromatin accessibility through their variable expression levels and diverse interactions with other TFs. We provide a theoretical basis for why cooperative TF binding – and any associated epigenomic mark – is inherently more variable than non-cooperative binding. Conclusions BROCKMAN and related approaches will help gain a mechanistic understanding of the trans determinants of chromatin variability between cells, treatments, and individuals. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource single cell, epigenome, chromatin, scATAC-seq, k-mer, N-gram Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12859-018-2255-6 Source A related resource from which the described resource is derived BMC Bioinformatics Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Computer applications to medicine. Medical informatics Language A language of the resource EN https://socictopen.socict.org/files/original/65a458701f5da475cd41a15f0355a2d8.pdf 70652851cfcf941b8190660f6ae5e21e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Broken Heart (Takotsubo) Syndrome Triggered by SARS-CoV-2. Creator An entity primarily responsible for making the resource Josef Finsterer Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1007/s42399-020-00703-4 Source A related resource from which the described resource is derived SN comprehensive clinical medicine