597
10
20655
-
https://socictopen.socict.org/files/original/899e6598112291e2211fb3730b3fb784.pdf
8d7ffab70c96a0475e945ca139b1e028
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Design, Synthesis and Biological Evaluation of Novel Primaquine-Cinnamic Acid Conjugates of the Amide and Acylsemicarbazide Type
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Kristina Pavić, Ivana Perković, Petra Gilja, Filip Kozlina, Katja Ester, Marijeta Kralj, Dominique Schols, Dimitra Hadjipavlou-Litina, Eleni Pontiki, Branka Zorc
Description
An account of the resource
In this paper design and synthesis of a scaffold comprising primaquine (PQ) motif and cinnamic acid derivatives (CADs) bound directly (compounds 3a–k) or via a spacer (compounds 7a–k) are reported. In the first series of compounds, PQ and various CADs were connected by amide bonds and in the second series by acylsemicarbazide functional groups built from the PQ amino group, CONHNH spacer and the carbonyl group originating from the CADs. PQ-CAD amides 3a–k were prepared by a simple one-step condensation reaction of PQ with a series of CAD chlorides (method A) or benzotriazolides 2 (method B). The synthesis of acylsemicarbazides 7a–k included activation of PQ with benzotriazole, preparation of PQ-semicarbazide 6 and its condensation with CAD chlorides 4. All synthesized PQ-CAD conjugates were evaluated for their anticancer, antiviral and antioxidative activities. Almost all compounds from series 3 were selective towards the MCF-7 cell line and active at micromolar concentrations. The o-fluoro derivative 3h showed high activity against HeLa, MCF-7 and in particular against the SW 620 cell line, while acylsemicarbazide 7f with a benzodioxole ring and 7c, 7g and especially 7j with methoxy-, chloro- or trifluoromethyl-substituents in the para position showed high selectivity and high inhibitory activity against MCF-7 cell line at micromolar (7c, 7f, 7g) and nanomolar (7j) levels. Acylsemicarbazide derivatives with trifluoromethyl group(s) 7i, 7j and 7k showed specific activity against human coronavirus (229E) at concentrations which did not alter the normal cell morphology. The same compounds exerted the most potent reducing activity in the DPPH test, together with 7d and 7g, while methoxy (compounds 7c–e), benzodioxole (7f), p-Cl (7g) and m-CF3 (7i) acylsemicarbazides and amide 3f presented the highest LP inhibition (83%–89%). The dimethoxy derivative 7d was the most potent LOX inhibitor (IC50 = 10 μΜ). The performed biological tests gave evidence of acylsemicarbazide functional group as superior binding group in PQ-CAD conjugates.
Date
A point or period of time associated with an event in the lifecycle of the resource
2016
Subject
The topic of the resource
primaquine, cinnamic acid derivative, conjugate, cytostatic activity, antiviral activity, antioxidative activity
Identifier
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DOI: 10.3390/molecules21121629
Source
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Molecules
Publisher
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MDPI AG
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Organic chemistry
Language
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EN
-
https://socictopen.socict.org/files/original/e000ea211e7f53fbd65e2e155e2b9054.pdf
26b27190d52e44d1e6b711624bf86f81
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
Creator
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Addila Abu Bakar, Muhammad Nadeem Akhtar, Norlaily Mohd Ali, Swee Keong Yeap, Ching Kheng Quah, Wan-Sin Loh, Noorjahan Banu Alitheen, Seema Zareen, Zaheer Ul-Haq, Syed Adnan Ali Shah
Description
An account of the resource
Flavokawain B (1) is a natural chalcone extracted from the roots of Piper methysticum, and has been proven to be a potential cytotoxic compound. Using the partial structure of flavokawain B (FKB), about 23 analogs have been synthesized. Among them, compounds 8, 13 and 23 were found in new FKB derivatives. All compounds were evaluated for their cytotoxic properties against two breast cancer cell lines, MCF-7 and MDA-MB-231, thus establishing the structure–activity relationship. The FKB derivatives 16 (IC50 = 6.50 ± 0.40 and 4.12 ± 0.20 μg/mL), 15 (IC50 = 5.50 ± 0.35 and 6.50 ± 1.40 μg/mL) and 13 (IC50 = 7.12 ± 0.80 and 4.04 ± 0.30 μg/mL) exhibited potential cytotoxic effects on the MCF-7 and MDA-MB-231 cell lines. However, the methoxy group substituted in position three and four in compound 2 (IC50 = 8.90 ± 0.60 and 6.80 ± 0.35 μg/mL) and 22 (IC50 = 8.80 ± 0.35 and 14.16 ± 1.10 μg/mL) exhibited good cytotoxicity. The lead compound FKB (1) showed potential cytotoxicity (IC50 = 7.70 ± 0.30 and 5.90 ± 0.30 μg/mL) against two proposed breast cancer cell lines. It is evident that the FKB skeleton is unique for anticancer agents, additionally, the presence of halogens (Cl and F) in position 2 and 3 also improved the cytotoxicity in FKB series. These findings could help to improve the future drug discovery process to treat breast cancer. A molecular dynamics study of active compounds revealed stable interactions within the active site of Janus kinase. The structures of all compounds were determined by 1H-NMR, EI-MS, IR and UV and X-ray crystallographic spectroscopy techniques.
Date
A point or period of time associated with an event in the lifecycle of the resource
2018
Subject
The topic of the resource
chalcone synthesis, breast cancer cell lines, SARS, anticancer, flavokawain B derivatives
Identifier
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DOI: 10.3390/molecules23030616
Source
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Molecules
Publisher
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MDPI AG
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Organic chemistry
Language
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EN
-
https://socictopen.socict.org/files/original/c1d6585ff1b44a0930333dba3e9f6453.pdf
e89455d83888e6f9e5ea9f9d00af8acc
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
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Title
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Design, Synthesis and Investigation of the Potential Anti-Inflammatory Activity of 7-<i>O</i>-Amide Hesperetin Derivatives
Creator
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Yilong Zhang, Yan Zheng, Wen Shi, Yahui Guo, Tao Xu, Zeng Li, Cheng Huang, Jun Li
Description
An account of the resource
To develop new anti-inflammatory agents, a series of 7-O-amide hesperetin derivatives was designed, synthesized and evaluated for anti-inflammatory activity using RAW264.7 cells. All compounds showed inhibitory effect on LPS-induced NO production. Among them, 7-O-(2-(Propylamino)-2-oxoethyl)hesperetin (4d) and 7-O-(2-(Cyclopentylamino)-2-oxoethyl)hesperetin (4k) with hydrophobic side chains exhibited the most potent NO inhibitory activity (IC50 = 19.32 and 16.63 μM, respectively), showing stronger inhibitory effect on the production of pro- inflammatory cytokines tumor necrosis factor (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) than indomethacin and celecoxib at 10 μM. The structure-activity relationships (SARs) suggested that the 7-O-amide unit was buried in a medium-sized hydrophobic cavity of the bound receptor. Furthermore, compound 4d could also significantly suppress the expression of inducible nitric oxide synthase enzymes (iNOS) and cyclooxygenase-2 (COX-2), through the nuclear factor-kappa B (NF-κB) signaling pathway.
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
Subject
The topic of the resource
hesperetin derivatives, Synthesis, Inflammatory, NF-κB, structure-activity relationships
Identifier
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DOI: 10.3390/molecules24203663
Source
A related resource from which the described resource is derived
Molecules
Publisher
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MDPI AG
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Organic chemistry
Language
A language of the resource
EN
-
https://socictopen.socict.org/files/original/4d24c641e051c54f497de5bcf4b09a74.pdf
bcc4444ee413a3e04d6a7868724dba70
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
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Title
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Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents
Creator
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Tao Wang, Tao Peng, Xiaoxue Wen, Gang Wang, Yunbo Sun, Shuchen Liu, Shou-Guo Zhang, Lin Wang
Description
An account of the resource
In this work, a series of benzylsulfone coumarin derivatives 5a−5o were synthesized and characterized. Kinase inhibitory activity assay indicated that most of the compounds showed considerable activity against PI3K. Anti-tumor activity studies of the active compounds were also carried out in vitro on the Hela, HepG2, H1299, HCT-116, and MCF-7 tumor cell lines by MTS assay. The structure−activity relationships (SARs) of these compounds were analyzed in detail. Compound 5h exhibited the most potent activities against the mentioned cell lines with IC50 values ranging from 18.12 to 32.60 μM, followed by 5m with IC50 values of 29.30−42.14 μM. Furthermore, 5h and 5m clearly retarded the migration of Hela cells in vitro. Next, an in silico molecular docking study was conducted to evaluate the binding models of 5h and 5m towards PI3Kα and PI3Kβ. Collectively, the above findings suggested that compounds 5h and 5m might be promising PI3K inhibitors deserving further investigation for cancer treatment.
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
Subject
The topic of the resource
benzylsulfone, coumarins, phosphoinositide 3-kinase (PI3K), anticancer, cell migration, molecular docking
Identifier
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DOI: 10.3390/molecules24224034
Source
A related resource from which the described resource is derived
Molecules
Publisher
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MDPI AG
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Organic chemistry
Language
A language of the resource
EN
-
https://socictopen.socict.org/files/original/a5891e4c0d95fc971984c8177e0cad3c.pdf
852735caf87dd8eedba03d85532921a7
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
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Title
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Design, Synthesis, Activity and Docking Study of Sorafenib Analogs Bearing Sulfonylurea Unit
Creator
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Chunjiang Wu, Min Wang, Qidong Tang, Rong Luo, Le Chen, Pengwu Zheng, Wufu Zhu
Description
An account of the resource
Two series of novel sorafenib analogs containing a sulfonylurea unit were synthesized and their chemical structures were confirmed by 1H-NMR, 13C-NMR, MS spectrum and elemental analysis. The synthesized compounds were evaluated for the cytotoxicity against A549, Hela, MCF-7, and PC-3 cancer cell lines. Some of the compounds showed moderate cytotoxic activity, especially compounds 1-(2,4-difluorophenylsulfonyl)-3-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea (6c) and 1-(4-bromophenylsulfonyl)-3-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea (6f) with the IC50 values against four cancer cell lines ranging from 16.54 ± 1.22 to 63.92 ± 1.81 μM, respectively. Inhibitory rates against vascular endothelial growth factor receptor-2 (VEGFR2/KDR) kinase at 10 μM of target compounds were further carried out in this paper in order to investigate the target of these compounds. Structure-activity relationships (SARs) and docking studies indicated that the sulfonylurea unit was important to these kinds of compounds. None of the substitutions in the phenoxy group and small halogen atoms such as 2,4-difluoro substitution of the aryl group contributed to the activity. The results suggested that sulfonylurea sorafenib analogs are worthy of further study.
Date
A point or period of time associated with an event in the lifecycle of the resource
2015
Subject
The topic of the resource
Sorafenib, Sulfonylurea, VEGFR2/KDR kinase inhibitors, anti-cancer activity
Identifier
An unambiguous reference to the resource within a given context
DOI: 10.3390/molecules201019361
Source
A related resource from which the described resource is derived
Molecules
Publisher
An entity responsible for making the resource available
MDPI AG
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Organic chemistry
Language
A language of the resource
EN
-
https://socictopen.socict.org/files/original/67c57cc655e237c4c78d8d47ec984098.pdf
f2a15739c16ee80a22394615f0657cee
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2.
Creator
An entity primarily responsible for making the resource
Leike Zhang, Hong Liu, Yechun Xu, Rolf Hilgenfeld, Wenhao Dai, Dirk Jochmans, Hang Xie, Hang Yang, Jian Li, Haixia Su, Di Chang, Jiang Wang, Jingjing Peng, Lili Zhu, Yong Nian, Hualiang Jiang, Kaixian Chen, Johan Neyts
Description
An account of the resource
A novel series of peptidomimetic aldehydes was designed and synthesized to target 3C protease (3Cpro) of enterovirus 71 (EV71). Most of the compounds exhibited high antiviral activity, and among them, compound 18p demonstrated potent enzyme inhibitory activity and broad-spectrum antiviral activity on a panel of enteroviruses and rhinoviruses. The crystal structure of EV71 3Cpro in complex with 18p determined at a resolution of 1.2 Å revealed that 18p covalently linked to the catalytic Cys147 with an aldehyde group. In addition, these compounds also exhibited good inhibitory activity against the 3CLpro and the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially compound 18p (IC50 = 0.034 μM, EC50 = 0.29 μM). According to our previous work, these compounds have no reasons for concern regarding acute toxicity. Compared with AG7088, compound 18p also exhibited good pharmacokinetic properties and more potent anticoronavirus activity, making it an excellent lead for further development.
Date
A point or period of time associated with an event in the lifecycle of the resource
2021
Identifier
An unambiguous reference to the resource within a given context
10.1021/acs.jmedchem.0c02258
Source
A related resource from which the described resource is derived
Journal of medicinal chemistry
-
https://socictopen.socict.org/files/original/eed708cdb9ea3da51c99fbf24a812b3c.pdf
8a2e2182e35fdb38542f2b3bc2f5e7ef
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Designing a resilient supply chain: An approach to reduce drug shortages in epidemic outbreaks
Creator
An entity primarily responsible for making the resource
Román Rodríguez Aguilar, Jose Lozano-Diez, Jose Marmolejo-Saucedo
Description
An account of the resource
INTRODUCTION: Supply network design is a long-studied topic that has evolved to address disruptive situations. The risk of supply chain disruption leads to the development of resilient supply chains that are capable of reacting effectively. OBJECTIVES: In the context of public health, drug supply networks face shortage challenges in many situations, such as current epidemic outbreaks such as COVID-19. Drug shortages can occur due to manufacturing problems, lack of infrastructure, and immediate reaction mechanisms. METHODS: The case study is solved with anyLogistix optimization and simulation software. RESULTS: We present the results of a hypothetical study on the impact of COVID-19 on a regional supply network. The results of this research are intended to be the basis for the design of resilient supply chains in epidemic outbreaks. CONCLUSION: Drug providers should consider strategies to prevent or reduce the impact of shortages as well as disruption spreads.
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
Subject
The topic of the resource
Dynamic simulation, drug shortages, supply chain design, resilient supply chain, COVID-19, Epidemic Outbreaks
Identifier
An unambiguous reference to the resource within a given context
DOI: 10.4108/eai.13-7-2018.164260
Source
A related resource from which the described resource is derived
EAI Endorsed Transactions on Pervasive Health and Technology
Publisher
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European Alliance for Innovation (EAI)
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Medicine, Medical technology
-
https://socictopen.socict.org/files/original/432cab1e12a183b8c974189fa3d14a1c.pdf
75919f454d53ba035d6b0d1678194b02
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Designing a SARS-CoV-2 T-Cell-Inducing Vaccine for High-Risk Patient Groups
Creator
An entity primarily responsible for making the resource
Hans-Georg Rammensee, Cécile Gouttefangeas, Sonja Heidu, Reinhild Klein, Beate Preuß, Juliane Sarah Walz, Annika Nelde, Sebastian P. Haen, Michael Reth, Jianying Yang, Ghazaleh Tabatabai, Hans Bösmüller, Helen Hoffmann, Michael Schindler, Oliver Planz, Karl-Heinz Wiesmüller, Markus W. Löffler
Description
An account of the resource
We describe the results of two vaccinations of a self-experimenting healthy volunteer with SARS-CoV-2-derived peptides performed in March and April 2020, respectively. The first set of peptides contained eight peptides predicted to bind to the individual’s HLA molecules. The second set consisted of ten peptides predicted to bind promiscuously to several HLA-DR allotypes. The vaccine formulation contained the new TLR 1/2 agonist XS15 and was administered as an emulsion in Montanide as a single subcutaneous injection. Peripheral blood mononuclear cells isolated from blood drawn before and after vaccinations were assessed using Interferon-γ ELISpot assays and intracellular cytokine staining. We detected vaccine-induced CD4 T cell responses against six out of 11 peptides predicted to bind to HLA-DR after 19 days, following vaccination, for one peptide already at day 12. We used these results to support the design of a T-cell-inducing vaccine for application in high-risk patients, with weakened lymphocyte performance. Meanwhile, an according vaccine, incorporating T cell epitopes predominant in convalescents, is undergoing clinical trial testing.
Date
A point or period of time associated with an event in the lifecycle of the resource
2021
Subject
The topic of the resource
covid-19, SARS-CoV-2, adjuvant, peptide vaccine, lipopeptide, high-risk patient
Identifier
An unambiguous reference to the resource within a given context
10.3390/vaccines9050428
Source
A related resource from which the described resource is derived
Epidemiology and Health
Publisher
An entity responsible for making the resource available
Korean Society of Epidemiology
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Medicine
-
https://socictopen.socict.org/files/original/21a93e0024b673b3ae3e7dee236f727d.pdf
60f2dd7e52d8868b7ff3c5913e9300cd
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Coronavirus
Description
An account of the resource
Dominio científico: Coronavirus
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Designing Multi-Epitope Vaccines to Combat Emerging Coronavirus Disease 2019 (COVID-19) by Employing Immuno-Informatics Approach
Creator
An entity primarily responsible for making the resource
Tariq Tahir Butt, Anam Naz, Fatima Shahid, Faryal Mehwish Awan, Amjad Ali, Arif Malik
Description
An account of the resource
A recent pandemic caused by a single-stranded RNA virus, COVID-19, initially discovered in China, is now spreading globally. This poses a serious threat that needs to be addressed immediately. Genome analysis of SARS-CoV-2 has revealed its close relation to SARS-coronavirus along with few changes in its spike protein. The spike protein aids in receptor binding and viral entry within the host and therefore represents a potential target for vaccine and therapeutic development. In the current study, the spike protein of SARS-CoV-2 was explored for potential immunogenic epitopes to design multi-epitope vaccine constructs. The S1 and S2 domains of spike proteins were analyzed, and two vaccine constructs were prioritized with T-cell and B-cell epitopes. We adapted a comprehensive predictive framework to provide novel insights into immunogenic epitopes of spike proteins, which can further be evaluated as potential vaccine candidates against COVID-19. Prioritized epitopes were then modeled using linkers and adjuvants, and respective 3D models were constructed to evaluate their physiochemical properties and their possible interactions with ACE2, HLA Superfamily alleles, TLR2, and TLR4.
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
Subject
The topic of the resource
coronavirus, spike protein, covid-19, s1 domain, corona vaccine, S2 domain
Identifier
An unambiguous reference to the resource within a given context
10.3389/fimmu.2020.01663
Source
A related resource from which the described resource is derived
Epidemiology and Health
Publisher
An entity responsible for making the resource available
Korean Society of Epidemiology
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Immunologic diseases. Allergy
-
https://socictopen.socict.org/files/original/0140f25b275f62689fe3c0d327d36ade.pdf
fcdb591342791130366b46f97390f28a
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Agricultura sostenible
Description
An account of the resource
Dominio científico: Agricultura sostenible
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Designing of an Enterprise Resource Planning for the Optimal Management of Agricultural Plots Regarding Quality and Environmental Requirements
Creator
An entity primarily responsible for making the resource
Marina Cano-Lamadrid, Damián Aguilar Morales, Paola Sánchez-Bravo, Leontina Lipan, Hanán Issa-Issa, Francisco J. del Campo-Gomis, David B. López Lluch
Description
An account of the resource
One of the main current problems in European quality agricultural production is the lack of objective data for linking quality to origin and to evidence environmental concern (CO2 uptake and use of water in Spain). The aim of this study was to develop an agricultural management platform, based on Enterprise Resource Planning (ERP) principles and with the ability to collect geolocated information from different plots related to Protected Designation of Origin (PDO) and Protected Geographical Indication (PGI) wine production. First a survey to farmers, technicians and PDO and PGI managers was carried out to detect the needs of the three groups in relation to ERP platforms; and secondly an ERP platform was developed to collect agronomic information to comply with the Spanish legal requirements. Results showed that the end user completes information database, complies with the legal requirements, and obtains benefits derived from the data analysis. Consequently, the platform (i) solves lack of agricultural data problem; (ii) provides the user with management tools for its agricultural operations; (iii) allows the decision maker to obtain geolocated information in real time; and (iv) sets out the bases for the future development of agricultural systems based on Big Data.
Date
A point or period of time associated with an event in the lifecycle of the resource
2020
Subject
The topic of the resource
ERP, GIS, Quality, environment, internet of things, precision agriculture
Identifier
An unambiguous reference to the resource within a given context
10.3390/agronomy10091352
Source
A related resource from which the described resource is derived
Agronomy
Publisher
An entity responsible for making the resource available
MDPI AG
Coverage
The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant
Agriculture
Relation
A related resource
<a href="https://www.mdpi.com/2073-4395/10/9/1352" target="_blank" rel="noreferrer noopener">https://www.mdpi.com/2073-4395/10/9/1352</a>