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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>EFECTO DE SUSTRATOS ORGÁNICOS EN EL CRECIMIENTO DE SEIS VARIEDADES DE CHILE JALAPEÑO (Capsicum annuum L.)/E�ect of organic substrates on the growth of six varieties of jalapeño (Capsicum annuum L.)</text>
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                <text>Felix Alfredo Beltrán-Morales, José Luis García-Hernández, Francisco Higinio Ruiz-Espinoza, Ricardo David Valdez-Cepeda, Pablo Preciado-Range, Manuel Fortis-Hernández, Alberto González-Zamora</text>
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                <text>. Un buen número de productores de hortalizas interesados en la agricultura orgánica, no pueden participaren este nicho de mercado debido a la escasa disponibilidad de fertilizantes orgánicos que satisfagan las necesidadesnutrimentales de los cultivos, que los fertilizantes químicos, además de biológicos y ecológicos. Se utilizaron tresdiferentes fuentes de fertilización en seis genotipos de chile jalapeño, los tratamientos fueron estiércol bovino, vermicompostay un testigo con fertilizante químico. Los genotipos se colectaron en el norte de México, el manejo delcultivo se realizó de acuerdo con la normatividad orgánica de los Estados Unidos. Los resultados mostraron que lavermicomposta suministró todos los nutrimentos necesarios para el crecimiento del chile. Los genotipos Euforia y DonJulio presentaron el mayor crecimiento y desarrollo en las variables evaluadas</text>
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                <text>2016</text>
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                <text>Agricultura orgânica, abono orgánico, agroecologia, nutrición vegetal, sustratos</text>
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                <text>Ecosistemas y Recursos Agropecuarios</text>
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                <text>Universidad Juárez Autónoma de Tabasco</text>
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                <text>Agriculture</text>
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                <text>&lt;a href="http://era.ujat.mx/index.php/rera/article/view/963/704" target="_blank" rel="noreferrer noopener"&gt;http://era.ujat.mx/index.php/rera/article/view/963/704&lt;/a&gt;</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Delimitación de áreas sociales en el barrio de la Concepción : un ensayo de ecología factorial a escala microespacial</text>
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                <text>Felix Aparicio Pérez, Gloria Lora Tamayo D'Ocón</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Desde que en 1965 F.L. Sweester realizará sobre la ciudad de Helsinki el primer análisis de Ecología Factorial —entendiendo como tal, la aplicación de las técnicas de Análisis Factorial a los datos que describen la diferenciación residencial de la población—, se han realizado numerosos estudios de ciudades, sobre todo americanas, dentro de este campo. Los análisis de Ecología Factorial aplicados a ciudades han respaldado, en términos generales, la hipótesis del Modelo de Áreas Sociales de E. Shevky y W. Bell (1955), poniendo de relieve, como factores fundamentales de diferenciación social, el Status Económico o Rango Social y el Status Familiar, y como factores secundarios, que no aparecen en muchos casos, el Status Étnico y la Movilidad de la Población.</text>
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            <name>Date</name>
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                <text>1991</text>
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            <name>Identifier</name>
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                <text>10.5944/etfvi.4.1991.2489</text>
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                <text>Espacio, Tiempo y Forma. Serie VI, Geografía</text>
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            <name>Publisher</name>
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              <elementText elementTextId="190693">
                <text>Universidad Nacional de Educación a Distancia (UNED)</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Geography (General), Geography. Anthropology. Recreation, Human ecology. Anthropogeography, Cities. Urban geography</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://revistas.uned.es/index.php/ETFVI/article/view/2489" target="_blank" rel="noreferrer noopener"&gt;http://revistas.uned.es/index.php/ETFVI/article/view/2489&lt;/a&gt;</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
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                <text>Coronavirus Disease-2019: Knowledge, Attitude, and Practices of Health Care Workers at Makerere University Teaching Hospitals, Uganda</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="30034">
                <text>Felix Bongomin, Ronald Olum, Gaudencia Chekwech, Godfrey Wekha, Dianah Rhoda Nassozi</text>
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                <text>Background: Coronavirus disease-2019 (COVID-19) is an emerging public health problem threatening the life of over 2.4 million people globally. The present study sought to determine knowledge, attitude and practices (KAP) of health care workers (HCWs) toward COVID-19 in Makerere University Teaching Hospitals (MUTHs) in Uganda.Methods: An online cross sectional, descriptive study was undertaken through WhatsApp Messenger among HCWs in four MUTHs. HCWs aged 18 years and above constituted the study population. KAP toward COVID-19 was assessed by using a pre-validated questionnaire. Bloom's cut-off of 80% was used to determine sufficient knowledge (≥80%), positive attitude (≥4), and good practice (≥2.4). All analyses were performed using STATA 15.1 and GraphPad Prism 8.3.Results: Of the 581 HCWs approached, 136 (23%) responded. A vast majority of the participants were male (n = 87, n = 64%), with a median age of 32 (range: 20–66) years. Eighty-four (62%) were medical doctors and 125 (92%) had at least a bachelor's degree. Overall, 69% (n = 94) had sufficient knowledge, 21% (n = 29) had positive attitude, and 74% (n = 101) had good practices toward COVID-19. Factors associated with knowledge were age &amp;gt;40 years (aOR: 0.3; 95% CI: 0.1–1.0; p = 0.047) and news media (aOR: 4.8; 95% CI: 1.4–17.0; p = 0.015). Factors associated with good practices were age 40 years or more (aOR: 48.4; 95% CI: 3.1–742.9; p = 0.005) and holding a diploma (aOR: 18.4; 95% CI: 1–322.9; p = 0.046).Conclusions: Continued professional education is advised among HCWs in Uganda to improve knowledge of HCWs hence averting negative attitudes and promoting positive preventive and therapeutic practices. We recommend follow up studies involving teaching and non-teaching hospitals across the country.</text>
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                <text>2020</text>
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                <text>healthcare workers, Uganda, KAPs, COVID-19, Makerere University Teaching Hospitals</text>
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              <elementText elementTextId="30038">
                <text>DOI: 10.3389/fpubh.2020.00181</text>
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                <text>Frontiers in Public Health</text>
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                <text>Frontiers Media S.A.</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Public aspects of medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>At the heart of COVID-19.</text>
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                <text>Felix Clemens Richter</text>
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                <text>10.1038/s41577-020-00468-w</text>
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                <text>Nature reviews. Immunology</text>
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                <text>Visit to Singapore Medical Journal during COVID-19 outbreak: learning “beyond” the expectation</text>
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                <text>Felix Firyanto Widjaja, Windu Cahyaningrum Handayani Notonagoro Suryaningrat</text>
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              <elementText elementTextId="14162">
                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="14163">
                <text>editorial</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="14164">
                <text>DOI: 10.13181/mji.ed.204615</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="14165">
                <text>Medical Journal of Indonesia</text>
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            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="14166">
                <text>Faculty of Medicine Universitas Indonesia</text>
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                <text>Medicine (General)</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>EN</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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            <name>Title</name>
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              <elementText elementTextId="197405">
                <text>La variabilidad climática de baja frecuencia en la modelación no estacionaria de los regímenes de las crecidas en las regiones hidrológicas Sinaloa y Presidio San Pedro</text>
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              <elementText elementTextId="197406">
                <text>Félix Francés, Jesús López-de-la-Cruz</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="197407">
                <text>El asumir estacionaridad ha sido una de las premisas principales en el estudio de las componentes del ciclo hidrológico y la piedra angular en el análisis de frecuencia de eventos extremos. La estacionaridad ha sido una hipótesis común y práctica en la planificación y gestión derecursos hídricos. A partir de ella se han usado métodos estadísticos para extraer de los datos todos los indicadores hidrológicos útiles para proporcionar estimaciones, donde estas estimaciones pueden ser refinadas año con año conforme los registros en las estaciones hidrométricas se hacen más largos. En años recientes, diversos estudios han demostrado que los registros hidrológicos presentan algún tipo de no estacionaridad, como cambios y tendencias, lo cual ha llevado a los expertos a un consenso, en el sentido de que la hipótesis de estacionaridad a nivel de cuenca se encuentra comprometida. Entre los principales mecanismos que han sido sugeridos como los inductores de cambios en el ciclo hidrológico de las cuencas y en la magnitud y frecuencia de las crecidas se encuentran los efectos de la intervención humana (p. ej., cambio de uso de suelo, embalses), el efecto de la variabilidad climática de baja frecuencia (p. ej., El Niño-Oscilación del Sur, Oscilación Decadal del Pacífico) y el cambio climático debido al incremento de los gases a la atmósfera. El objetivo del presente estudio yace en el desarrollo de un marco para análisis de frecuencia bajo condiciones de no estacionaridad por medio de los Modelos Aditivos Generalizados en Localización, Escala y Forma (GAMLSS por sus siglas en inglés). Dos diferentes aproximaciones para la modelación estadística no estacionaria fueron las aplicadas a los registros de caudales instantáneos máximos anuales en las regiones hidrológicas Sinaloa y Presidio San Pedro en el noroeste del Pacífico mexicano. Estos modelos consisten básicamente en el modelo con incorporación de tendencias temporales en los parámetros de las distribuciones paramétricas y el modelo con incorporación del forzamiento de la variabilidad climática de baja frecuencia. Los resultados en la primera aproximación muestran la capacidad de los modelos para describir la variabilidad presente en los regímenes de crecidas; asimismo, se observa la alta dependencia de los parámetros de las distribuciones paramétricas respecto del tiempo, lo cual sugiere la ausencia de estacionaridad en los regímenes de crecidas en las estaciones de aforo de estudio. En el segundo enfoque, en el cual los índices climáticos (Niño12, Niño3, Niño3.4, SOI y PDO) que describen el comportamiento de los patrones de variabilidad de baja frecuencia fueron incorporados como covariables explicativas en los modelos, permiten resaltar el importante papel de los fenómenos de macroescala que ocurren en el Pacífico, en la variabilidad interanual de los regímenes de las crecidas en la costa del Pacífico mexicano. Además, la comparación de los modelos en la inferencia de cuantiles entre los modelos no estacionarios respecto del clásico modelo estacionario muestra que las diferencias obtenidas asumiendo no estacionaridad y sus equivalentes estacionarios pueden ser importantes durante extensos periodos de tiempo.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="197408">
                <text>2014</text>
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            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="197409">
                <text>GAMLSS, Pacífico mexicano, análisis de frecuencia de crecidas, caudales máximos anuales, no estacionaridad, patrones de  variabilidad  climática  de  baja  frecuencia</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="197410">
                <text>Tecnología y ciencias del agua</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="197411">
                <text>Instituto Mexicano de Tecnología del Agua</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="197412">
                <text>Hydraulic engineering, Water supply for domestic and industrial purposes</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="197413">
                <text>&lt;a href="http://www.revistatyca.org.mx/ojs/index.php/tyca/article/view/452" target="_blank" rel="noreferrer noopener"&gt;http://www.revistatyca.org.mx/ojs/index.php/tyca/article/view/452&lt;/a&gt;</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88122">
                  <text>Dominio científico: Agricultura sostenible</text>
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              </elementTextContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="203604">
                <text>Influencia de las tecnologías de labranza-siembra sobre los costos energéticos y de explotación de la técnica empleada y la contaminación del aire en el cultivo del frijol</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="203605">
                <text>Félix Ponce C., Enrique Álvarez T., Yorbis Gonzáles S., José I. Hernández A.</text>
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            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="203606">
                <text>Se evaluaron los costos energéticos, los costos de explotación y la emisión de contaminantes al aire de cuatro variantes tecnológicas para la labranza/siembra del cultivo de fríjol, según fuentes energéticas y aperos disponibles, en diferentes fincas de la Cooperativa de Crédito y Servicio (CCS) «Nelson Fernández», municipio San José de Las Lajas, provincia La Habana. En la tecnología 3, donde todas las operaciones tecnológicas se realizaron con tractor, los costos energéticos (11 681 MJ/ha y 9 984 MJ/t), los costos de explotación (89,4 pesos/ha y 81,20 pesos/t) y la polución a la atmósfera (983 kg/ha y 840 kg/t), fueron superiores a la tecnología 2, donde los costos energéticos (5 065 MJ/ha y 5 628 MJ/t), los costos de explotación (66,47 pesos/ha y 77,2 pesos/t) y la polución atmosférica fue de (515 kg/ha y 572 kg/t), empleando aperos más simples y combinados en la siembra con tracción animal.</text>
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            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="203607">
                <text>2008</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="203608">
                <text>Revista Ciencias Técnicas Agropecuarias</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="203609">
                <text>Universidad Agraria de La Habana</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="203610">
                <text>Agriculture, Environmental technology. Sanitary engineering</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="203611">
                <text>&lt;a href="http://www.redalyc.org/articulo.oa?id=93215942004" target="_blank" rel="noreferrer noopener"&gt;http://www.redalyc.org/articulo.oa?id=93215942004&lt;/a&gt;</text>
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  <item itemId="1895" public="1" featured="0">
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        <src>https://socictopen.socict.org/files/original/1f40d2f8aa5f481fcdedb15490f950b8.pdf</src>
        <authentication>59e015da670981605beef7a5fda17269</authentication>
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        <elementSet elementSetId="1">
          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="18171">
                <text>Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa</text>
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            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="18172">
                <text>Felix S. Dube, Mamadou Kaba, F. J. Lourens Robberts, Lemese Ah Tow, Sugnet Lubbe, Heather J. Zar, Mark P Nicol</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="18173">
                <text>Abstract Background Lower respiratory tract infection in children is increasingly thought to be polymicrobial in origin. Children with symptoms suggestive of pulmonary tuberculosis (PTB) may have tuberculosis, other respiratory tract infections or co-infection with Mycobacterium tuberculosis and other pathogens. We aimed to identify the presence of potential respiratory pathogens in nasopharyngeal (NP) samples from children with suspected PTB. Method NP samples collected from consecutive children presenting with suspected PTB at Red Cross Children’s Hospital (Cape Town, South Africa) were tested by multiplex real-time RT-PCR. Mycobacterial liquid culture and Xpert MTB/RIF was performed on 2 induced sputa obtained from each participant. Children were categorised as definite-TB (culture or qPCR [Xpert MTB/RIF] confirmed), unlikely-TB (improvement of symptoms without TB treatment on follow-up) and unconfirmed-TB (all other children). Results Amongst 214 children with a median age of 36 months (interquartile range, [IQR] 19–66 months), 34 (16 %) had definite-TB, 86 (40 %) had unconfirmed-TB and 94 (44 %) were classified as unlikely-TB. Moraxella catarrhalis (64 %), Streptococcus pneumoniae (42 %), Haemophilus influenzae spp (29 %) and Staphylococcus aureus (22 %) were the most common bacteria detected in NP samples. Other bacteria detected included Mycoplasma pneumoniae (9 %), Bordetella pertussis (7 %) and Chlamydophila pneumoniae (4 %). The most common viruses detected included metapneumovirus (19 %), rhinovirus (15 %), influenza virus C (9 %), adenovirus (7 %), cytomegalovirus (7 %) and coronavirus O43 (5.6 %). Both bacteria and viruses were detected in 73, 55 and 56 % of the definite, unconfirmed and unlikely-TB groups, respectively. There were no significant differences in the distribution of respiratory microbes between children with and without TB. Using quadratic discriminant analysis, human metapneumovirus, C. pneumoniae, coronavirus 043, influenza virus C virus, rhinovirus and cytomegalovirus best discriminated children with definite-TB from the other groups of children. Conclusions A broad range of potential respiratory pathogens was detected in children with suspected TB. There was no clear association between TB categorisation and detection of a specific pathogen. Further work is needed to explore potential pathogen interactions and their role in the pathogenesis of PTB.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="18174">
                <text>2016</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="18175">
                <text>infection, Nasopharynx, microbiota, Mycobacterium tuberculosis, Tuberculosis, Respiratory microbes</text>
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            </elementTextContainer>
          </element>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="18176">
                <text>DOI: 10.1186/s12879-016-1934-z</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="18177">
                <text>BMC Infectious Diseases</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="18178">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="18179">
                <text>Infectious and parasitic diseases</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="18180">
                <text>EN</text>
              </elementText>
            </elementTextContainer>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="20406">
                <text>Site-Specific Cleavage of RNAs Derived from the &lt;i&gt;PIM1&lt;/i&gt; 3′-UTR by a Metal-Free Artificial Ribonuclease</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="20407">
                <text>Felix Zellmann, Laura Thomas, Ute Scheffer, Roland K. Hartmann, Michael W. Göbel</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="20408">
                <text>Oligonucleotide conjugates of tris(2-aminobenzimidazole) have been reported previously to cleave complementary RNA strands with high levels of sequence and site specificity. The RNA substrates used in these studies were oligonucleotides not longer than 29-mers. Here we show that ~150&amp;#8315;400-mer model transcripts derived from the 3&amp;#8242;-untranslated region of the PIM1 mRNA reacted with rates and specificities comparable to those of short oligonucleotide substrates. The replacement of DNA by DNA/LNA mixmers further increased the cleavage rate. Tris(2-aminobenzimidazoles) were designed to interact with phosphates and phosphate esters. A cell, however, contains large amounts of phosphorylated species that may cause competitive inhibition of RNA cleavage. It is thus important to note that no loss in reaction rates was observed in phosphate buffer. This opens the way to in-cell applications for this type of artificial nuclease. Furthermore, we disclose a new synthetic method giving access to tris(2-aminobenzimidazoles) in multigram amounts.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="20409">
                <text>2019</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="20410">
                <text>2-aminobenzimidazole, cleavage of large RNA molecules, cleavage site selection, DNA/LNA mixmers, dye labeling, guanidine analogs, oligonucleotides, specificity of cleavage</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="20411">
                <text>DOI: 10.3390/molecules24040807</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="20412">
                <text>Molecules</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="20413">
                <text>MDPI AG</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="20414">
                <text>Organic chemistry</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="20415">
                <text>EN</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
  <item itemId="2642" public="1" featured="0">
    <fileContainer>
      <file fileId="2642">
        <src>https://socictopen.socict.org/files/original/a932e19eb349370361c90e493551155c.pdf</src>
        <authentication>de48ebaebca0d9c3a2bdb22098d99225</authentication>
      </file>
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        <elementSet elementSetId="1">
          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="25110">
                <text>Association of the insulin resistance marker TyG index with the severity and mortality of COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="25111">
                <text>Fen Wang, Yan Yang, Shujun Zhang, Kun Dong, Xiaoli Shi, Yongli Yan, Xue-Feng Yu, Huihui Ren</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="25112">
                <text>Abstract Background The triglyceride and glucose index (TyG) has been proposed as a marker of insulin resistance. This study aims to evaluate the association of the TyG index with the severity and mortality of coronavirus disease 2019 (COVID-19). Methods The study included a cohort of 151 patients with COVID-19 admitted in a tertiary teaching hospital in Wuhan. Regression models were used to investigate the association between TyG with severity and mortality of COVID-19. Results In this cohort, 39 (25.8%) patients had diabetes, 62 (41.1%) patients were severe cases, while 33 (22.0%) patients died in hospital. The TyG index levels were significantly higher in the severe cases and death group (mild vs. severe 8.7 ± 0.6 vs. 9.2 ± 0.6, P </text>
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            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="25113">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="25114">
                <text>Mortality, Severity, TyG index, COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="25115">
                <text>DOI: 10.1186/s12933-020-01035-2</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="25116">
                <text>Cardiovascular Diabetology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="25117">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="25118">
                <text>Diseases of the circulatory (Cardiovascular) system</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
