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Cellular RNA Helicase DDX1 Is Involved in Transmissible Gastroenteritis Virus nsp14-Induced Interferon-Beta Production
Transmissible gastroenteritis virus (TGEV), an enteropathogenic coronavirus (CoV) of porcine, causes lethal watery diarrhea and severe dehydration in piglets and leads to severe economic losses in the swine industry. Unlike most CoVs that antagonize…
Position: 13067 (15 views)
Adverse drug reactions associated with six commonly used antiepileptic drugs in southern China from 2003 to 2015
Abstract Background This active, open observational study aimed to investigate adverse drug reactions (ADRs) associated with six commonly used antiepileptic drugs (AEDs) in southern Chinese outpatients with epilepsy from 2003 to 2015. Methods The…
Position: 14625 (14 views)
Analisis Risiko Produk Alat Pelindung Diri (APD) Pencegah Penularan COVID-19 untuk Pekerja Informal di Indonesia
The Coronavirus Disease of 2019 (COVID-19) that is transmitted through the human respiratory system has a very high infection rate worldwide, including Indonesia. To cut off this outbreak, Indonesia has implemented some social distancing strategies…
Position: 19448 (10 views)
Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication.
Virus-induced apoptosis and viral mechanisms that regulate this cell death program are key issues in understanding virus-host interactions and viral pathogenesis. Like many other human and animal viruses, coronavirus infection of mammalian cells…
Position: 6290 (20 views)
Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication.
Virus-induced apoptosis and viral mechanisms that regulate this cell death program are key issues in understanding virus-host interactions and viral pathogenesis. Like many other human and animal viruses, coronavirus infection of mammalian cells…
Position: 8656 (18 views)
Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7.
For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed. We previously identified the antiviral activities of the scorpion-venom-peptide-derived…
Position: 4539 (22 views)
Application of embedded computer and improved genetic algorithm in the strategy of community of human destiny: the development of artificial intelligence in the context of Covid-19.
Through the COVID-19 epidemic in 2020, the society has deeply realized the inevitability and necessity of building a community that shares the future of mankind. In the face of severely complex international trends and domestic and international…
Position: 20422 (8 views)
History of coronary heart disease increased the mortality rate of patients with COVID-19: a nested case–control study
Objective Evaluate the risk of pre-existing comorbidities on COVID-19 mortality, and provide clinical suggestions accordingly.Setting A nested case–control design using confirmed case reports released from the news or the…
Position: 7374 (19 views)
Study on Glacial Tourism Exploitation in the Dagu Glacier Scenic Spot Based on the AHP–ASEB Method
Due to the impact of COVID-19, people’s demand for non-contact tourism is increasing. The development of Internet technologies such as the Internet of Things, virtual reality (VR), and augmented reality (AR) can meet this demand. Internet technology…
Position: 14625 (14 views)
Pulmonary, cardiac and renal distribution of ACE2, furin, TMPRSS2 and ADAM17 in rats with heart failure: Potential implication for COVID-19 disease.
Congestive heart failure (CHF) is often associated with kidney and pulmonary dysfunction. Activation of the renin-angiotensin-aldosterone system (RAAS) contributes to avid sodium retention, cardiac hypertrophy and oedema formation, including lung…
Position: 13067 (15 views)