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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Alphacoronaviruses in New World bats: prevalence, persistence, phylogeny, and potential for interaction with humans.</text>
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                <text>Christina Osborne, Paul M. Cryan, Thomas J O'Shea, Lauren M. Oko, Christina Ndaluka, Charles H Calisher, Andrew D Berglund, Mead L Klavetter, Richard A. Bowen, Kathryn V. Holmes, Samuel R. Dominguez</text>
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                <text>Bats are reservoirs for many different coronaviruses (CoVs) as well as many other important zoonotic viruses. We sampled feces and/or anal swabs of 1,044 insectivorous bats of 2 families and 17 species from 21 different locations within Colorado from 2007 to 2009. We detected alphacoronavirus RNA in bats of 4 species: big brown bats (Eptesicus fuscus), 10% prevalence; long-legged bats (Myotis volans), 8% prevalence; little brown bats (Myotis lucifugus), 3% prevalence; and western long-eared bats (Myotis evotis), 2% prevalence. Overall, juvenile bats were twice as likely to be positive for CoV RNA as adult bats. At two of the rural sampling sites, CoV RNAs were detected in big brown and long-legged bats during the three sequential summers of this study. CoV RNA was detected in big brown bats in all five of the urban maternity roosts sampled throughout each of the periods tested. Individually tagged big brown bats that were positive for CoV RNA and later sampled again all became CoV RNA negative. Nucleotide sequences in the RdRp gene fell into 3 main clusters, all distinct from those of Old World bats. Similar nucleotide sequences were found in amplicons from gene 1b and the spike gene in both a big-brown and a long-legged bat, indicating that a CoV may be capable of infecting bats of different genera. These data suggest that ongoing evolution of CoVs in bats creates the possibility of a continued threat for emergence into hosts of other species. Alphacoronavirus RNA was detected at a high prevalence in big brown bats in roosts in close proximity to human habitations (10%) and known to have direct contact with people (19%), suggesting that significant potential opportunities exist for cross-species transmission of these viruses. Further CoV surveillance studies in bats throughout the Americas are warranted.</text>
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                <text>2011</text>
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                <text>DOI: 10.1371/journal.pone.0019156</text>
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                <text>PLoS ONE</text>
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                <text>Public Library of Science (PLoS)</text>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Altamirano, Teófilo. Refugiados ambientales. Cambio climático y migración forzada. Lima: Fondo Editorial de la Pontificia Universidad Católica del Perú, 2014, 226 pp.</text>
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                <text>Fernando Bravo Alarcón</text>
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            <name>Date</name>
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                <text>2014</text>
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          <element elementId="48">
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            <description>A related resource from which the described resource is derived</description>
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                <text>Anthropologica</text>
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                <text>Pontificia Universidad Católica del Perú</text>
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                <text>Geography. Anthropology. Recreation, Anthropology</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://revistas.pucp.edu.pe/index.php/anthropologica/article/view/11333" target="_blank" rel="noreferrer noopener"&gt;http://revistas.pucp.edu.pe/index.php/anthropologica/article/view/11333&lt;/a&gt;</text>
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              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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            <name>Title</name>
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                <text>Alteração de atributos químicos do solo pela utilização prolongada de esterco de suínos no sistema plantio direto</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Cristiano Nunes  Nesi, Ivan Tadeu Baldissera, Eloi Erhard Scherer</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Este trabalho é baseado em dois experimentos de campo, conduzidos na Região Oeste de Santa Catarina, com utilização de esterco de suínos e adubo nitrogenado em milho no sistema plantio direto. Para o estudo foram coletadas amostras de solo nas profundidades de zero a 5, 5 a 10 e 10 a 20cm, com o objetivo de avaliar o efeito da adubação com esterco (zero, 40 e 115m3/ha) e nitrogênio (zero, 60 e 120kg/ha) nas características químicas do solo. A utilização de esterco de suínos em aplicação superficial, no sistema plantio direto, afeta as características do solo principalmente na camada de zero a 5cm. A sua utilização por um período de três a quatro anos na adubação do milho afetou os teores de matéria orgânica, CTC e fósforo disponível na camada superficial do solo. As alterações observadas foram proporcionais à dose aplicada. Os teores de K, Ca, Mg e Al trocáveis e o pH não foram afetados pela aplicação de esterco e adubo nitrogenado. O fósforo teve pouca mobilidade e acumulou-se em maiores quantidades na camada de zero a 5cm.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2021</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Adubação, Latossolo, dejetos animais, dinámica de nutrientes</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="226245">
                <text>Revista Agropecuária Catarinense</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="226246">
                <text>Empresa de Pesquisa Agropecuária e Extensão Rural de Santa Catarina - Epagri</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Agriculture (General)</text>
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            <description>A related resource</description>
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              <elementText elementTextId="226248">
                <text>&lt;a href="https://publicacoes.epagri.sc.gov.br/RAC/article/view/936" target="_blank" rel="noreferrer noopener"&gt;https://publicacoes.epagri.sc.gov.br/RAC/article/view/936&lt;/a&gt;</text>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="88122">
                  <text>Dominio científico: Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
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      <name>Text</name>
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                <text>Alteración de la fertilidad del suelo, y vulnerabilidad de maíz y trigo bajo riego debido al cambio climático</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Liliana Terrazas Mendoza, Iourii Nikolskii Gavrilov, Sergio Santiago Herrera Gómez, Marcial Castillo Álvarez, Adolfo Antenor Exebio García</text>
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            <description>An account of the resource</description>
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                <text>La estimación de la vulnerabilidad de los cultivos por efectos del cambio climático ha sido realizada principalmente para los cultivos de temporal, asumiendo que no existe alteración de la fertilidad del suelo atribuible al cambio climático. El objetivo principal del presente trabajo fue estimar el papel de modificación del índice integral de fertilidad del suelo en los cálculos de la productividad de los cultivos de maíz de grano y trigo en varios distritos de riego de México. Se ha desarrollado una metodología para predecir la alteración de algunas propiedades del suelo bajo riego y su índice integral de fertilidad, atribuibles al cambio climático. Los resultados de la investigación señalan que la sensibilidad de los suelos agrícolas bajo riego en México al cambio climático es menor que los suelos agrícolas de temporal y suelos sin uso agrícola (vírgenes); sin afectar significativamente la vulnerabilidad de los cultivos al cambio climático. La principal afectación por la alteración de la fertilidad del suelo en estimaciones de vulnerabilidad de los cultivos bajo riego se espera en las zonas climáticas semiárida, semihúmeda y húmeda tropical de México, donde el índice climático adimensional promedio anual IHT es menor de 2.5.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="177567">
                <text>2010</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>ley geográfica de zonificación de suelos, índice climático, índice integral de fertilidad</text>
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          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="177569">
                <text>Tecnología y ciencias del agua</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="177570">
                <text>Instituto Mexicano de Tecnología del Agua</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Hydraulic engineering, Water supply for domestic and industrial purposes</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://www.revistatyca.org.mx/ojs/index.php/tyca/article/view/48" target="_blank" rel="noreferrer noopener"&gt;http://www.revistatyca.org.mx/ojs/index.php/tyca/article/view/48&lt;/a&gt;</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Alteraciones del paisaje ecológico araucano por la asimilación mapuche de la agroganadería hispano-mediterránea (siglos XVI y XVII) Araucanian ecological landscape disturbances by the mapuche assimilation of the Hispanic-Mediterranean farming (16th and 17th centuries)</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="167945">
                <text>FERNANDO TORREJÓN, MARCO CISTERNAS</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="167946">
                <text>Las características biogeográficas de la América templada favorecieron la introducción y propagación de especies animales y vegetales que sustentaron al modelo agroganadero hispano-mediterráneo. Los efectos de este fenómeno generaron alteraciones ecológicas, especialmente en los territorios habitados por aborígenes carentes de actividades productivas intensivas, como fue el caso de la Araucanía. Mediante un análisis histórico documental, la presente investigación reconoció las principales características del proceso de alteración del paisaje ecológico araucano entre los siglos XVI y XVII: (i) en el siglo XVI, la introducción de especies exóticas desarticuló el sistema económico mapuche, (ii) tanto la relativa pristinidad de la Araucanía como el proceso bélico de los siglos XVI y XVII, favorecieron la introducción y propagación de las nuevas especies, (iii) durante el siglo XVI coexistieron especies nativas e introducidas, sin embargo, durante el siglo XVII preponderaron las exóticas, y (iv) este predominio habría generado la extinción local de especies animales y vegetales nativas, alterando definitivamente el paisaje ecológico araucanoThe bio-geographic characteristics of the temperate America favored the introduction and spreading of exotic plant and animal species that supported the Hispanic-Mediterranean farming model. The effects of this situation produced ecological alterations on the territories inhabited by Indians without intense productive systems; as the Araucanía case. Through a historical and documental analysis this paper reports the main characteristics of the Araucanian ecological landscape disruption process during the 16th and 17th centuries: (i) during the 16th century, the introduction of exotic species dislocated the Mapuche economic system, (ii) both the relative Araucanía pristine conditions and the warlike process, occurred between the 16th and 17th centuries, favored the introduction and spreading of the new species, (iii) during the 16th century, both natives and exotic species coexisted, but during the next century the exotic species predominated, and (iv) this preponderance would have produced a local extinction of native plants and animals, disrupting definitively the Araucanian ecological landscape.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="167947">
                <text>2002</text>
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          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="167948">
                <text>Araucanía, Chile, Ecología del paisaje, Introducción de especies, Spanish settlement, colonización española, ecological landscape, species introduction</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="167949">
                <text>Revista Chilena de Historia Natural</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="167950">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="167951">
                <text>Botany, Zoology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="167952">
                <text>&lt;a href="http://www.scielo.cl/scielo.php?script=sci_arttext&amp;amp;pid=S0716-078X2002000400008" target="_blank" rel="noreferrer noopener"&gt;http://www.scielo.cl/scielo.php?script=sci_arttext&amp;amp;pid=S0716-078X2002000400008&lt;/a&gt;</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88121">
                  <text>Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="88122">
                  <text>Dominio científico: Agricultura sostenible</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
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                <text>Alterações químicas em solo submetido a diferentes formas de manejo do cafeeiro</text>
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            </elementTextContainer>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="239172">
                <text>Theodoro V. C. A., Alvarenga M. I. N., Guimarães R. J., Souza C. A. S.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="239173">
                <text>A difusão de pacotes tecnológicos que preconizam o uso de altas dosagens de adubos químicos e o controle de pragas e doenças, como métodos para manter o potencial produtivo das lavouras, obriga o produtor a utilizar aplicações sistemáticas de fertilizantes inorgânicos e pesticidas, o que vem afetando a sustentabilidade do agroecossistema cafeeiro, gerando uma total dependência de insumos industrializados. O objetivo deste estudo foi relacionar as mudanças nas características químicas, físicas e microbiológicas de um Latossolo Vermelho distrófico (LVd), da região de Santo Antônio do Amparo (MG), sob agroecossistemas de produção de 'café orgânico', 'em conversão' e 'convencional', em relação a um fragmento de mata nativa. Em duas fazendas sob influência de condições similares de clima e relevo, apresentando o mesmo cultivar (Acaiá IAC474-19) e idade da lavoura (cinco anos), foi realizado um levantamento de dados por um período de um ano. O solo foi amostrado na profundidade de 0-20 cm, em duas épocas (julho/1999 e dezembro/1999). A análise de componentes principais permitiu uma visualização conjunta das características que mais influíram no comportamento do solo dos diferentes sistemas estudados. De modo geral, as formas de manejo para produção de café orgânico, em conversão e convencional, proporcionaram aumentos na fertilidade do solo, quando comparados com a condição do solo do fragmento de mata nativa. No agroecossistema de produção de café orgânico, foram obtidas maiores alterações das características químicas em relação ao convencional; houve incrementos no pH e nos valores de Ca, Mg, K, P, Zn, B, CTC do solo, soma de bases, saturação por bases e diminuição do Al trocável.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="239174">
                <text>2003</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="239175">
                <text>Agricultura orgânica, Características, Coffea arabica, manejo do solo</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="239176">
                <text>Revista Brasileira de Ciência do Solo</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="239177">
                <text>Sociedade Brasileira de Ciência do Solo</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="239178">
                <text>Agriculture (General)</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="239179">
                <text>&lt;a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;amp;pid=S0100-06832003000600008" target="_blank" rel="noreferrer noopener"&gt;http://www.scielo.br/scielo.php?script=sci_arttext&amp;amp;pid=S0100-06832003000600008&lt;/a&gt;</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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            <description>A name given to the resource</description>
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                <text>Alteration of consciousness as initial presentation in COVID-19: Observation</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="23152">
                <text>Viroj Wiwanitkit, Beuy Joob</text>
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            <name>Date</name>
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              <elementText elementTextId="23153">
                <text>2020</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="23154">
                <text>DOI: 10.4103/aian.AIAN_123_20</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="23155">
                <text>Annals of Indian Academy of Neurology</text>
              </elementText>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="23156">
                <text>Wolters Kluwer Medknow Publications</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="23157">
                <text>Neurology. Diseases of the nervous system</text>
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  <item itemId="316" public="1" featured="0">
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
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                <text>Alterations in nerve-evoked bladder contractions in a coronavirus-induced mouse model of multiple sclerosis.</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="2921">
                <text>Neil S Lamarre, Alan S Braverman, Anna P Malykhina, Mary F. Barbe, Michael R Ruggieri</text>
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                <text>Patients with neurodegenerative diseases such as multiple sclerosis, Parkinson's, and Alzheimer's often present with lower urinary tract symptoms (LUTS, urinary frequency, urgency, nocturia and retention) resulting from damage to the peripheral and central nervous systems. These studies were designed to examine the changes in the function of the bladder that may underlie neurogenic bladder dysfunction using a mouse model of demyelination in the CNS.Bladders from 12 week old male C57BL/6J mice with coronavirus-induced encephalomyelitis (CIE, a chronic, progressive demyelinating disease model of human MS), and age-matched controls, were cut into 5-7 strips and suspended in physiological muscle baths for tension measurement in response to agonists and electric field stimulation (EFS). Experiments were performed on intact and denuded (with mucosa removed) bladder strips.The maximum effect of EFS was not significantly different between CIE and control bladders. Nerve-evoked EFS contractions (tetrodotoxin-sensitive) were blocked by a combination of atropine (cholinergic antagonist) and α,β-methylene ATP (an ATP analog that desensitizes purinergic receptors). In response to EFS, the α,β-methylene ATP-resistant (cholinergic) component of contraction was significantly reduced, while the atropine-resistant (purinergic) component was significantly increased in CIE bladders. Removal of the mucosa in CIE bladders restored the cholinergic component. Bethanechol (muscarinic receptor agonist) potency was significantly increased in CIE bladders.Our data demonstrate a deficit in the nerve-evoked cholinergic component of contraction that is not due to the ability of the smooth muscle to respond to acetylcholine. We conclude that neurodegenerative bladder dysfunction in this model of multiple sclerosis may be due, in part, to pathologic changes in the mucosa that causes suppression of muscarinic receptor-mediated contractile response and augmentation of purinergic response of the underlying muscle. Further studies utilizing CIE mice should help elucidate the pathological changes in the mucosa resulting from demyelination in the CNS.</text>
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                <text>2014</text>
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              <elementText elementTextId="2924">
                <text>DOI: 10.1371/journal.pone.0109314</text>
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              <elementText elementTextId="2925">
                <text>PLoS ONE</text>
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                <text>Public Library of Science (PLoS)</text>
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                <text>Science, Medicine</text>
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                <text>EN</text>
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              <description>An account of the resource</description>
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                <text>Altered immunoemotional regulatory system in COVID-19: From the origins to opportunities.</text>
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                <text>Nima Rezaei, Homa Pourriyahi, Amene Saghazadeh</text>
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            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="63787">
                <text>The emergence of the novel coronavirus (SARS-CoV-2) and the worldwide spread of the coronavirus disease (COVID-19) have led to social regulations that caused substantial changes in manners of daily life. The subsequent loneliness and concerns of the pandemic during social distancing, quarantine, and lockdown are psychosocial stressors that negatively affect the immune system. These effects occur through mechanisms controlled by the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenocortical (HPA) axis that alter immune regulation, namely the conserved transcriptional response to adversity (CTRA), which promotes inflammation and diminishes antiviral responses, leading to inadequate protection against viral disease. Unhealthy eating habits, physical inactivity, sleep disturbances, and mental health consequences of COVID-19 add on to the pathological effects of loneliness, making immunity against this ferocious virus an even tougher fight. Therefore, social isolation, with its unintended consequences, has inherently paradoxical effects on immunity in relation to viral disease. Though this paradox can present a challenge, its acknowledgment can serve as an opportunity to address the associated issues and find ways to mitigate the adverse effects. In this review, we aim to explore, in detail, the pathological effects of the new social norms on immunity and present suggested methods to improve our physical, psychological, and healthcare abilities to fight viral infection in the context of the COVID-19 pandemic.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="63788">
                <text>2021</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="63789">
                <text>quarantine, covid-19, Pandemic, Stress, loneliness, immune regulation, Immune booster, CTRA, Hypothalamic-pituitary-adrenocortical axis, IMMERS, Immunoemotional regulatory system</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="63790">
                <text>10.1016/j.jneuroim.2021.577578</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="63791">
                <text>Journal of neuroimmunology</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
  <item itemId="7076" public="1" featured="0">
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      <file fileId="7076">
        <src>https://socictopen.socict.org/files/original/f73e4a4088653579616722ce0c3202b6.pdf</src>
        <authentication>05603dc73b4b1828f06cc317a143c941</authentication>
      </file>
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        <elementSet elementSetId="1">
          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
    </itemType>
    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="62321">
                <text>Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="62322">
                <text>Qi Wu, Lina Zhou, Xin Sun, Zhongfang Yan, Chunxiu Hu, Junping Wu, Long Xu, Xue Li, Huiling Liu, Peiyuan Yin, Kuan Li, Jieyu Zhao, Yanli Li, Xiaolin Wang, Yu Li, Qiuyang Zhang, Guowang Xu, Huaiyong Chen</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="62323">
                <text>Abstract Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-like coronavirus are a potential threat to global health. However, reviews of the long-term effects of clinical treatments in SARS patients are lacking. Here a total of 25 recovered SARS patients were recruited 12 years after infection. Clinical questionnaire responses and examination findings indicated that the patients had experienced various diseases, including lung susceptibility to infections, tumors, cardiovascular disorders, and abnormal glucose metabolism. As compared to healthy controls, metabolomic analyses identified significant differences in the serum metabolomes of SARS survivors. The most significant metabolic disruptions were the comprehensive increase of phosphatidylinositol and lysophospha tidylinositol levels in recovered SARS patients, which coincided with the effect of methylprednisolone administration investigated further in the steroid treated non-SARS patients with severe pneumonia. These results suggested that high-dose pulses of methylprednisolone might cause long-term systemic damage associated with serum metabolic alterations. The present study provided information for an improved understanding of coronavirus-associated pathologies, which might permit further optimization of clinical treatments.</text>
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            </elementTextContainer>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="62324">
                <text>2017</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="62325">
                <text>10.1038/s41598-017-09536-z</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="62326">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="62327">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="62328">
                <text>Science, Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
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    </elementSetContainer>
  </item>
</itemContainer>
