154 10 20655 https://socictopen.socict.org/files/original/f025ea4cf58e9ff4b432944b80a095ec.pdf 6b2d6e25e3f7fcdc23b3aad368a6d863 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Discovery and Characterization of Novel RNA Viruses in Aquatic North American Wild Birds Creator An entity primarily responsible for making the resource Andrew S. Lang, Marta Canuti, Ashley N. K. Kroyer, Davor Ojkic, Hugh G. Whitney, Gregory J. Robertson Description An account of the resource Wild birds are recognized viral reservoirs but our understanding about avian viral diversity is limited. We describe here three novel RNA viruses that we identified in oropharyngeal/cloacal swabs collected from wild birds. The complete genome of a novel gull metapneumovirus (GuMPV B29) was determined. Phylogenetic analyses indicated that this virus could represent a novel avian metapneumovirus (AMPV) sub-group, intermediate between AMPV-C and the subgroup of the other AMPVs. This virus was detected in an American herring (1/24, 4.2%) and great black-backed (4/26, 15.4%) gulls. A novel gull coronavirus (GuCoV B29) was detected in great black-backed (3/26, 11.5%) and American herring (2/24, 8.3%) gulls. Phylogenetic analyses of GuCoV B29 suggested that this virus could represent a novel species within the genus Gammacoronavirus, close to other recently identified potential novel avian coronaviral species. One GuMPV&#8722;GuCoV co-infection was detected. A novel duck calicivirus (DuCV-2 B6) was identified in mallards (2/5, 40%) and American black ducks (7/26, 26.9%). This virus, of which we identified two different types, was fully sequenced and was genetically closest to other caliciviruses identified in Anatidae, but more distant to other caliciviruses from birds in the genus Anas. These discoveries increase our knowledge about avian virus diversity and host distributions. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource coronavirus, Virus-Discovery, Calicivirus, metapneumovirus, viral epidemiology, avian viruses, novel viruses Identifier An unambiguous reference to the resource within a given context 10.3390/v11090768 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://socictopen.socict.org/files/original/60877b517b8c977824282d58e3955fa3.pdf 93cee3b8c1c4e17cf8a6d65d92c5260b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Yin and Yang of SARS-CoV-2 Mutation and Evolution. Creator An entity primarily responsible for making the resource Andrew D Badley Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.mayocp.2021.01.023 Source A related resource from which the described resource is derived Mayo Clinic proceedings https://socictopen.socict.org/files/original/9c1d04c4586b3e9213d1650c58c35eb5.pdf a8cb70678ffa084b2b304a748958c0b8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Redefining Medicine's Relationship With the Media in the Era of COVID-19. Creator An entity primarily responsible for making the resource Andrew D Carlo, Brian S Barnett, Utibe R Essien, Sandro Galea Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.amepre.2020.08.016 Source A related resource from which the described resource is derived American journal of preventive medicine https://socictopen.socict.org/files/original/a98e92485fab8724e6678ee794aceb20.pdf 063f6260d6164a384cf32bcbbccd3a47 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Ciudadanía ecológica: ¿una influencia desestabilizadora? Creator An entity primarily responsible for making the resource Andrew Dobson Description An account of the resource En este artículo se abordan dos cuestiones diferentes, aunque interconectadas. La primera es: ¿puede articularse una política de la ecología en términos de ciudadanía? Mi respuesta a esta pregunta es afirmativa, presentando una propuesta de «ciudadanía ecológica». Esto conduce a la segunda cuestión: ¿cómo afecta la ciudadanía ecológica a la noción misma de ciudadanía? Esta cuestión se responde mediante la articulación de una «arquitectura » de la teoría de la ciudadanía que se organiza a través de las oposiciones entre derechos y deberes, la esfera pública y la privada, la ciudadanía activa y la pasiva y, por último, entre las concepciones «territorializadas » y «desterritorializadas» de la ciudadanía. Se defiende que la noción de ciudadanía ecológica desestabiliza la arquitectura estándar de la ciudadanía al poner el énfasis en los deberes de los ciudadanos más que en los derechos; al sugerir que el ámbito privado es un espacio tan legítimo para la actividad ciudadana como el espacio público, al negar la asociación habitual entre la ciudadanía «pasiva» y el ámbito privado, y al revalidar las concepciones desterritorializadas de ciudadanía. Finalmente, se presenta la contribución de la ciudadanía ecológica a la «remoralización» de la política, y se trazan algunas de las tensiones resultantes de su confrontación con las exigencias de la democracia liberal. Date A point or period of time associated with an event in the lifecycle of the resource 2001 Identifier An unambiguous reference to the resource within a given context 10.3989/isegoria.2001.i24.610 Source A related resource from which the described resource is derived Isegoría Publisher An entity responsible for making the resource available Consejo Superior de Investigaciones Científicas Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Philosophy (General) Relation A related resource <a href="http://isegoria.revistas.csic.es/index.php/isegoria/article/view/610" target="_blank" rel="noreferrer noopener">http://isegoria.revistas.csic.es/index.php/isegoria/article/view/610</a> https://socictopen.socict.org/files/original/0e56a27b507f7a5ce4a9f7233cc77dfc.pdf 59eb65291ceae759eb67921fb06e207e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Intracranial Hypertension in Multisystem Inflammatory Syndrome in Children. Creator An entity primarily responsible for making the resource Andrew E Becker, Kathleen Chiotos, Jennifer L McGuire, Benjamin B Bruins, Alicia M Alcamo Description An account of the resource Multisystem inflammatory syndrome in children (MIS-C) is characterized by fever and multiorgan system dysfunction. Neurologic complications of MIS-C are not well described. We present 4 patients with MIS-C who had intracranial hypertension and discuss the unique management considerations when this occurs concurrently with significant myocardial dysfunction. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, SARS-CoV-2, Coronavirus disease 2019, pediatric, PIMs, myocardial dysfunction, Pediatric critical care, Increased intracranial pressure, PIM-TS, neurologic dysfunction Identifier An unambiguous reference to the resource within a given context 10.1016/j.jpeds.2021.02.062 Source A related resource from which the described resource is derived The Journal of pediatrics https://socictopen.socict.org/files/original/6e0da28125099cc1cd78b9f76125bef5.pdf 0f144db13e04cc558cb16fa655e51d52 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource CÓDIGOS DE BARRAS DE LA VIDA: INTRODUCCIÓN Y PERSPECTIVA Creator An entity primarily responsible for making the resource Andrew J. Crawford, Andrea Paz, Mailyn Gonzalez Description An account of the resource RESUMEN Los códigos de barra de ADN representan una iniciativa global para acumular cortas secuencias estandarizadas de ADN de la gran mayoría de las especies de eucariotas del planeta, con el propósito de facilitar la identificación y conocimiento de la biodiversidad. Después de ocho años de discusión y producción en la literatura científica, el tema sigue generando controversia, debido en parte a la falta de homogeneidad en la definición y el alcance del método entre los autores. En este artículo enfatizamos la definición y metodología de los códigos de barra de ADN, así como su uso para contestar preguntas nuevas en el campo de la ecología, la evolución y la conservación. Palabras clave: Bases de datos, Bioinformática, Códigos de barras de ADN, Diagnosis molecular, Sistemática filogenética, Genética evolutiva, Taxonomía. ABSTRACT DNA barcode of life is a global initiative to populate a global database of short, standardized DNA fragments from most eukaryotic species to facilitate the identification and understanding of the world’s biodiversity. In the eight years following its proposal, the topic of DNA barcoding remains controversial in the scientific literature due, in part, to a lack of consensus on how DNA barcoding is defined and what activities are included under this title. In the present paper we review the definition, methods and goals of DNA barcoding, and highlight how data generated by various DNA barcode of life campaigns may also be used to address fundamental and novel questions in ecology, evolution and conservation. Keywords: Bioinformatics, Databases, DNA barcode of life, Evolutionary genetics, Molecular diagnosis, Phylogenetic systematics, Taxonomy. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Source A related resource from which the described resource is derived Acta Biológica Colombiana Publisher An entity responsible for making the resource available Universidad Nacional de Colombia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General) Relation A related resource <a href="https://revistas.unal.edu.co/index.php/actabiol/article/view/19782" target="_blank" rel="noreferrer noopener">https://revistas.unal.edu.co/index.php/actabiol/article/view/19782</a> https://socictopen.socict.org/files/original/c117200a3dc6b48c11987c6b3937cd46.pdf 0160d69bd8bacc03fb339e7853d3f22d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy. Creator An entity primarily responsible for making the resource Andrew Jeremijenko, Peter Coyle, Abdullatif Al Khal, Ayeda A. Ahmed, Yasmin A. Mohamoud, Shameem Younuskunju, Houssein H. Ayoub, Zaina Al Kanaani, Einas Al Kuwari, Anvar Hassan Kaleeckal, Ali Nizar Latif, Riyazuddin Mohammad Shaik, Hanan F. Abdul Rahim, Mohamed Ghaith Al Kuwari, Hamad Eid Al Romaihi, Mohamed H. Al-Thani, Roberto Bertollini, Gheyath K Nasrallah, Laith J Abu-Raddad, Hiam Chemaitelly, Joel A Malek, Adeel A Butt, Hadi M Yassine Description An account of the resource Reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been documented, raising public health concerns. SARS-CoV-2 reinfections were assessed in a cohort of antibody-positive persons in Qatar. All SARS-CoV-2 antibody-positive persons from April 16 to December 31, 2020 with a PCR-positive swab ≥14 days after the first-positive antibody test were investigated for evidence of reinfection. Viral genome sequencing was conducted for paired viral specimens to confirm reinfection. Incidence of reinfection was compared to incidence of infection in the complement cohort of those who were antibody-negative. Among 43,044 antibody-positive persons who were followed for a median of 16.3 weeks (range: 0-34.6), 314 individuals (0.7%) had at least one PCR positive swab ≥14 days after the first-positive antibody test. Of these individuals, 129 (41.1%) had supporting epidemiological evidence for reinfection. Reinfection was next investigated using viral genome sequencing. Applying the viral-genome-sequencing confirmation rate, the incidence rate of reinfection was estimated at 0.66 per 10,000 person-weeks (95% CI: 0.56-0.78). Incidence rate of reinfection versus month of follow-up did not show any evidence of waning of immunity for over seven months of follow-up. Meanwhile, in the complement cohort of 149,923 antibody-negative persons followed for a median of 17.0 weeks (range: 0-45.6), incidence rate of infection was estimated at 13.69 per 10,000 person-weeks (95% CI: 13.22-14.14). Efficacy of natural infection against reinfection was estimated at 95.2% (95% CI: 94.1-96.0%). Reinfections were less severe than primary infections. Only one reinfection was severe, two were moderate, and none were critical or fatal. Most reinfections (66.7%) were diagnosed incidentally through random or routine testing, or through contact tracing. Reinfection is rare in the young and international population of Qatar. Natural infection appears to elicit strong protection against reinfection with an efficacy ~95% for at least seven months. Biomedical Research Program, the Biostatistics, Epidemiology, and Biomathematics Research Core, and the Genomics Core, all at Weill Cornell Medicine-Qatar, the Ministry of Public Health, Hamad Medical Corporation, and the Qatar Genome Programme. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource epidemiology, immunity, SARS-CoV-2, Reinfection, genetics Identifier An unambiguous reference to the resource within a given context 10.1016/j.eclinm.2021.100861 Source A related resource from which the described resource is derived EClinicalMedicine https://socictopen.socict.org/files/original/0cea92b0ae5a8671d36cbeb6dfd12a0e.pdf 99a07e68fcc6bb116f80aff7cf292eae Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling. Creator An entity primarily responsible for making the resource Andrew R Jauregui, Dhruti Savalia, Virginia K Lowry, Cara M Farrell, Marc G Wathelet Description An account of the resource An epidemic of Severe Acute Respiratory Syndrome (SARS) led to the identification of an associated coronavirus, SARS-CoV. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses. To gain a better understanding of nsp1 mode of action, we generated and analyzed 38 mutants of the SARS-CoV nsp1, targeting 62 solvent exposed residues out of the 180 amino acid protein. From this work, we identified six classes of mutants that abolished, attenuated or increased nsp1 inhibition of host gene expression and/or antiviral signaling. Each class of mutants clustered on SARS-CoV nsp1 surface and suggested nsp1 interacts with distinct host factors to exert its inhibitory activities. Identification of the nsp1 residues critical for its activities and the pathways involved in these activities should help in the design of drugs targeting nsp1. Significantly, several point mutants increased the inhibitory activity of nsp1, suggesting that coronaviruses could evolve a greater ability to evade the host response through mutations of such residues. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0062416 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://socictopen.socict.org/files/original/4fa0baa5b7210743933ca15fef39b259.pdf 7719049f7806f99d91541e3b25fd2a26 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Household COVID-19 risk and in-person schooling. Creator An entity primarily responsible for making the resource Andrew S Azman, C Jessica E Metcalf, Justin Lessler, M Kate Grabowski, Kyra H Grantz, Elena Badillo-Goicoechea, Carly Lupton-Smith, Elizabeth A Stuart Description An account of the resource In-person schooling has proved contentious and difficult to study throughout the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Data from a massive online survey in the United States indicate an increased risk of COVID-19-related outcomes among respondents living with a child attending school in person. School-based mitigation measures are associated with significant reductions in risk, particularly daily symptoms screens, teacher masking, and closure of extracurricular activities. A positive association between in-person schooling and COVID-19 outcomes persists at low levels of mitigation, but when seven or more mitigation measures are reported, a significant relationship is no longer observed. Among teachers, working outside the home was associated with an increase in COVID-19-related outcomes, but this association is similar to that observed in other occupations (e.g., health care or office work). Although in-person schooling is associated with household COVID-19 risk, this risk can likely be controlled with properly implemented school-based mitigation measures. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1126/science.abh2939 Source A related resource from which the described resource is derived Science (New York, N.Y.) https://socictopen.socict.org/files/original/79957a0aed3d5e8f1a78855916a0b798.pdf c57fe6bddba368b71821352503477cc4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. Creator An entity primarily responsible for making the resource Andrew S. Bell, James E Mills, Gareth P Williams, James A. Brannigan, Anthony J. Wilkinson, Tanya Parkinson, Robin J. Leatherbarrow, Edward W. Tate, Anthony A. Holder, Deborah F. Smith Description An account of the resource Inhibition of N-myristoyltransferase has been validated pre-clinically as a target for the treatment of fungal and trypanosome infections, using species-specific inhibitors. In order to identify inhibitors of protozoan NMTs, we chose to screen a diverse subset of the Pfizer corporate collection against Plasmodium falciparum and Leishmania donovani NMTs. Primary screening hits against either enzyme were tested for selectivity over both human NMT isoforms (Hs1 and Hs2) and for broad-spectrum anti-protozoan activity against the NMT from Trypanosoma brucei. Analysis of the screening results has shown that structure-activity relationships (SAR) for Leishmania NMT are divergent from all other NMTs tested, a finding not predicted by sequence similarity calculations, resulting in the identification of four novel series of Leishmania-selective NMT inhibitors. We found a strong overlap between the SARs for Plasmodium NMT and both human NMTs, suggesting that achieving an appropriate selectivity profile will be more challenging. However, we did discover two novel series with selectivity for Plasmodium NMT over the other NMT orthologues in this study, and an additional two structurally distinct series with selectivity over Leishmania NMT. We believe that release of results from this study into the public domain will accelerate the discovery of NMT inhibitors to treat malaria and leishmaniasis. Our screening initiative is another example of how a tripartite partnership involving pharmaceutical industries, academic institutions and governmental/non-governmental organisations such as Medical Research Council and Wellcome Trust can stimulate research for neglected diseases. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pntd.0001625 Source A related resource from which the described resource is derived PLoS Neglected Tropical Diseases Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine Language A language of the resource EN