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                <text>Objective: Handwashing is now considered as one of the best safety measures to prevent COVID-19 infection. The effect of excessive handwashing for health on OCD patients who are already having washing compulsion is not known. Furthermore, the fear of contamination of COVID-19 in patients who already have obsession of contamination is not known. This study aims to evaluate the effect of COVID-19 on OCD patients.  Method: Phone interviews were done with 84 patients previously diagnosed with obsession of contamination and compulsive washing. Yale Brown Obsessive Compulsive Scale was used and the scores of the participants were compared to their prepandemic scores.  Results: Only 5 patients (6%) had exacerbation of symptoms after the COVID-19 pandemic. Most of the patients did not report any deterioration of symptoms due to the pandemic.  Conclusion: Handwashing protocol does not aggravate the washing compulsion of patients. Similarly, the fear of infection with COVID-19 does not increase their fear of contamination.</text>
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                <text>The novel coronavirus disease (COVID-19) has become a global health crisis since its first appearance in Wuhan, China. Current epidemiological studies suggest that COVID-19 affects older patients with multiple comorbidities, such as hypertension, obesity, and chronic lung diseases. The differences in the incidence and severity of COVID-19 are likely to be multifaceted, depending on various biological, social, and economical factors. Specifically, the socioeconomic differences and psychological impact of COVID-19 affecting males and females are essential in pandemic mitigation and preparedness. Previous clinical studies have shown that females are less susceptible to acquire viral infections and reduced cytokine production. Female patients have a higher macrophage and neutrophil activity as well as antibody production and response. Furthermore, in-vivo studies of the angiotensin-converting enzyme 2 (ACE2) showed higher expression in the kidneys of male than female patients, which may explain the differences in susceptibility and progression of COVID-19 between male and female patients. However, it remains unknown whether the expression of ACE2 differs in the lungs of male or female patients. Disparities in healthcare access and socioeconomic status between ethnic groups may influence COVID-19 rates. Ethnic groups often have higher levels of medical comorbidities and lower socioeconomic status, which may increase their risk of contracting COVID-19 through weak cell-mediated immunity. In this article, we examine the current literature on the gender and racial differences among COVID-19 patients and further examine the possible biological mechanisms underlying these differences.</text>
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                <text>A Path to Soluble Molecularly Imprinted Polymers</text>
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                <text>Abhilasha Verma, George M. Murray</text>
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                <text>Molecular imprinting is a technique for making a selective binding site for a specific chemical. The technique involves building a polymeric scaffold of molecular complements containing the target molecule. Subsequent removal of the target leaves a cavity with a structural “memory” of the target. Molecularly imprinted polymers (MIPs) can be employed as selective adsorbents of specific molecules or molecular functional groups. In addition, sensors for specific molecules can be made using optical transduction through lumiphores residing in the imprinted site. We have found that the use of metal ions as chromophores can improve selectivity due to selective complex formation. The combination of molecular imprinting and spectroscopic selectivity can result in sensors that are highly sensitive and nearly immune to interferences. A weakness of conventional MIPs with regard to processing is the insolubility of crosslinked polymers. Traditional MIPs are prepared either as monoliths and ground into powders or are prepared in situ on a support. This limits the applicability of MIPs by imposing tedious or difficult processes for their inclusion in devices. The size of the particles hinders diffusion and slows response. These weaknesses could be avoided if a means were found to prepare individual macromolecules with crosslinked binding sites with soluble linear polymeric arms. This process has been made possible by controlled free radical polymerization techniques that can form pseudo-living polymers. Modern techniques of controlled free radical polymerization allow the preparation of block copolymers with potentially crosslinkable substituents in specific locations. The inclusion of crosslinkable mers proximate to the binding complex in the core of a star polymer allows the formation of molecularly imprinted macromolecules that are soluble and processable. Due to the much shorter distance for diffusion, the polymers exhibit rapid responses. This paper reviews the methods that have been employed for the trace determination of organophosphates in real world samples using MIPs.</text>
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                <text>2011</text>
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                <text>Molecular imprinting, molecularly imprinted polymers (MIPs), crosslinkable mers, organophosphates, lanthanide</text>
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                <text>DOI: 10.3390/jfb3010001</text>
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                <text>Journal of Functional Biomaterials</text>
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                <text>Medicine (General), Biotechnology</text>
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                <text>Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy</text>
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                <text>Abhinay Gontu, Sreenidhi Srinivasan, Eric Salazar, Meera Surendran Nair, Ruth H. Nissly, Denver Greenawalt, Ian M. Bird, Catherine M. Herzog, Matthew J. Ferrari, Indira Poojary, Robab Katani, Scott E. Lindner, Allen M. Minns, Randall Rossi, Paul A. Christensen, Brian Castillo, Jian Chen, Todd N. Eagar, Xin Yi, Picheng Zhao, Christopher Leveque, Randall J. Olsen, David W. Bernard, Jimmy Gollihar, Suresh V. Kuchipudi, James M. Musser, Vivek Kapur</text>
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                <text>Gontu et al. conducted a longitudinal study in COVID patients in which they assessed the response trajectories of antibodies directed to the SARS-CoV-2 surface spike glycoprotein and in vitro SARS-CoV-2 live virus neutralizing titers. Their measurements demonstrate the presence of an optimum window for convalescent plasma donation as well as predictions of the most suitable donor type.</text>
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                <text>2021</text>
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                <text>10.1038/s42003-021-01813-y</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Biology (General)</text>
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                <text>Comment on Acute Thrombosis of Lower Limbs Arteries in the Acute Phase and After Recovery From COVID19 Infection"."</text>
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                <text>Abhisekh Mohapatra</text>
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                <text>Annals of surgery</text>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Evaluating Risk and Possible Adaptations to Climate Change Under a Socio-Ecological System Approach</text>
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                <text>Abi Haro, Alma Mendoza-Ponce, Alma Mendoza-Ponce, Óscar Calderón-Bustamante, Julián A. Velasco, Francisco Estrada, Francisco Estrada, Francisco Estrada</text>
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                <text>Evidence suggests that climate change could drastically reduce Mexico's agricultural productivity with severe socio-ecological consequences. Population growth and the increasing demand of resources will exacerbate these impacts. Focusing on rainfed maize production, we evaluate the socio-ecological risk that municipalities currently face and how climate change could modify it. Municipalities were classified based on their biophysical and socioeconomic traits like temperature, precipitation, population, gross domestic product, marginalization, and agricultural subsidies. The study identifies municipalities that would face higher risk under climate change conditions, and it evaluates whether increases in agricultural subsidies could be effective for reducing the farmers' future risk. Our results show that during the 2010's, 36.8% of the municipalities and 15% of the population were at very high and high risk, respectively. By 2070, under a high-warming scenario these figures increase to 56.5 and 18.5%. We find that a generalized augment in agricultural subsidies is not enough to compensate for the effects of climate change on the socio-ecological risk of rainfed maize producers. We suggest that transformative adaptation is required for managing the agricultural risk that socio-ecological systems experience under climate change conditions. Such adaptation strategies should include poverty alleviation, promotion of resistant and native varieties of crops, capacity building to improve management and water use, sustainable technification, and soil restoration.</text>
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                <text>México, Risk assessment, climate change, maize, socio-ecological system</text>
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                <text>10.3389/fclim.2021.674693</text>
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                <text>Frontiers in Climate</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Environmental sciences</text>
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                <text>&lt;a href="https://www.frontiersin.org/articles/10.3389/fclim.2021.674693/full" target="_blank" rel="noreferrer noopener"&gt;https://www.frontiersin.org/articles/10.3389/fclim.2021.674693/full&lt;/a&gt;</text>
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