25 10 20655 https://socictopen.socict.org/files/original/0d6e8595f56834ead89742f6d7c28eef.pdf 2ef943c493c5cd44f1a1e299c21d34d8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 12th EEF Congress. 12º Congreso Europeo de Ecología Creator An entity primarily responsible for making the resource L. Jiménez-Eguizábal Date A point or period of time associated with an event in the lifecycle of the resource 2011 Source A related resource from which the described resource is derived Ecosistemas Publisher An entity responsible for making the resource available Asociación Española de Ecología Terrestre Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental sciences Relation A related resource <a href="http://www.redalyc.org/articulo.oa?id=54021285025" target="_blank" rel="noreferrer noopener">http://www.redalyc.org/articulo.oa?id=54021285025</a> https://socictopen.socict.org/files/original/5ecd7569009b3d8316e54cb503d99b5d.pdf e652af81b6b83b9bffbb1020357a12f9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 15 Smartphone Apps for Older Adults to Use While in Isolation During the COVID-19 Pandemic Creator An entity primarily responsible for making the resource Elizabeth M. Goldberg, Swechya Banskota, Margaret Healy Description An account of the resource The maintenance of well-being, healthcare, and social connection is crucial for older adults (OA) and has become a topic of debate as much of the world faces lockdown during the coronavirus disease 2019 (COVID-19) pandemic. OAs have been advised to isolate themselves because they are at higher risk for developing serious complications from severe acute respiratory syndrome coronavirus. Additionally, nursing homes and assisted-living facilities across the country have closed their doors to visitors to protect their residents. Mobile technology such as applications (apps) could provide a valuable tool to help families stay connected, and to help OAs maintain mobility and link them to resources that encourage physical and mental well-being. Apps could address cognitive, visual, and hearing impairments. Our objective was to narratively summarize 15 apps that address physical and cognitive limitations and have the potential to improve OAs’ quality of life, especially during social distancing or self-quarantine. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.5811/westjem.2020.4.47372 Source A related resource from which the described resource is derived Western Journal of Emergency Medicine Publisher An entity responsible for making the resource available eScholarship Publishing, University of California Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Medical emergencies. Critical care. Intensive care. First aid https://socictopen.socict.org/files/original/1512ce48296f9f2a0091b2040e1113f6.pdf 46db059e7cbda3fde16bdd5c8fabfe1a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 17 Days in Warsan, Dubai, UAE, for COVID-19 Creator An entity primarily responsible for making the resource Jasem Alhashmi Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1159/000508553 Source A related resource from which the described resource is derived Dubai Medical Journal Publisher An entity responsible for making the resource available Karger Publishers Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://socictopen.socict.org/files/original/c5561084ebbb4a8c15e914873dc00599.pdf 6ca633fac4550fedac14ed22303c8b4a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 19.- Experiencia educativa: Práctica de huertos familiares y escolares en la zona rural Capachalito, Municipio Tovar, Estado Aragua Creator An entity primarily responsible for making the resource María Moreno Jaimes Description An account of the resource El desarrollo local desde la práctica de los huertos familiares y escolares está vinculado a políticas públicas del Gobierno venezolano relacionado con la agricultura urbana, generando en esta investigación un plan de acción en la zona rural Capachalito, Municipio Tovar, Estado Aragua, para mejorar la calidad de vida de sus habitantes, incentivando a representantes, estudiantes y docentes a retomar la práctica de huertos escolares, dentro del Programa de Alimentación Escolar (PAE), apoyando los postulados de soberanía y seguridad alimentaria. Epistemológicamente se sustentó en el Paradigma Socio Crítico desde la perspectiva de Habermas (1987), con enfoque cualitativo, método de Investigación Acción Participativa (IAP) apoyado con la observación participante. El procesamiento de información se realizó mediante la clasificación, nudos críticos y síntesis categorial para construir estrategias de acción y evaluación de experiencias, permitiendo destacar la importancia del desarrollo endógeno y la agricultura sustentable comunitaria, para rescatar los saberes tradicionales vinculados a la siembra de huertos familiares y escolares. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Desarrollo endógeno, Huertos Familiares y Escolares, desarrollo local Identifier An unambiguous reference to the resource within a given context 10.46498/reduipb.v25i3.1544 Source A related resource from which the described resource is derived Educare Publisher An entity responsible for making the resource available Universidad Pedagógica Experimental Libertador Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Special aspects of education, Education (General), History of education, Theory and practice of education Relation A related resource <a href="https://revistas.investigacion-upelipb.com/index.php/educare/article/view/1544" target="_blank" rel="noreferrer noopener">https://revistas.investigacion-upelipb.com/index.php/educare/article/view/1544</a> https://socictopen.socict.org/files/original/a4080e021fe3318eb0f1647ea85008ea.pdf 68a6e0ad3b216f1352a57a1bb61a2ea1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 1D-Var multilayer assimilation of X-band SAR data into a detailed snowpack model Creator An entity primarily responsible for making the resource X. V. Phan, L. Ferro-Famil, M. Gay, Y. Durand, M. Dumont, S. Morin, S. Allain, G. D'Urso, A. Girard Description An account of the resource The structure and physical properties of a snowpack and their temporal evolution may be simulated using meteorological data and a snow metamorphism model. Such an approach may meet limitations related to potential divergences and accumulated errors, to a limited spatial resolution, to wind or topography-induced local modulations of the physical properties of a snow cover, etc. Exogenous data are then required in order to constrain the simulator and improve its performance over time. Synthetic-aperture radars (SARs) and, in particular, recent sensors provide reflectivity maps of snow-covered environments with high temporal and spatial resolutions. The radiometric properties of a snowpack measured at sufficiently high carrier frequencies are known to be tightly related to some of its main physical parameters, like its depth, snow grain size and density. SAR acquisitions may then be used, together with an electromagnetic backscattering model (EBM) able to simulate the reflectivity of a snowpack from a set of physical descriptors, in order to constrain a physical snowpack model. In this study, we introduce a variational data assimilation scheme coupling TerraSAR-X radiometric data into the snowpack evolution model Crocus. The physical properties of a snowpack, such as snow density and optical diameter of each layer, are simulated by Crocus, fed by the local reanalysis of meteorological data (SAFRAN) at a French Alpine location. These snowpack properties are used as inputs of an EBM based on dense media radiative transfer (DMRT) theory, which simulates the total backscattering coefficient of a dry snow medium at X and higher frequency bands. After evaluating the sensitivity of the EBM to snowpack parameters, a 1D-Var data assimilation scheme is implemented in order to minimize the discrepancies between EBM simulations and observations obtained from TerraSAR-X acquisitions by modifying the physical parameters of the Crocus-simulated snowpack. The algorithm then re-initializes Crocus with the modified snowpack physical parameters, allowing it to continue the simulation of snowpack evolution, with adjustments based on remote sensing information. This method is evaluated using multi-temporal TerraSAR-X images acquired over the specific site of the Argentière glacier (Mont-Blanc massif, French Alps) to constrain the evolution of Crocus. Results indicate that X-band SAR data can be taken into account to modify the evolution of snowpack simulated by Crocus. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Identifier An unambiguous reference to the resource within a given context DOI: 10.5194/tc-8-1975-2014 Source A related resource from which the described resource is derived The Cryosphere Publisher An entity responsible for making the resource available Copernicus Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental sciences, Geology Language A language of the resource EN https://socictopen.socict.org/files/original/24ee73e9cadb4bf47e2fbc6d5948f987.pdf ffb97abf7190228ddad41829f99da341 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 1H, 13C, 15N and 31P chemical shift assignment for stem-loop 4 from the 5'-UTR of SARS-CoV-2. Creator An entity primarily responsible for making the resource Stephen A Peter, Nusrat S Qureshi, Julia E Weigand, Jennifer Vögele, Jan-Peter Ferner, Nadide Altincekic, Jasleen Kaur Bains, Betül Ceylan, Boris Fürtig, J Tassilo Grün, Martin Hengesbach, Katharina F Hohmann, Daniel Hymon, Bozana Knezic, Frank Löhr, Dennis Pyper, Christian Richter, Andreas Schlundt, Harald Schwalbe, Elke Stirnal, Alexey Sudakov, Anna Wacker, Julia Wirmer-Bartoschek, Jens Wöhnert, Elke Duchardt-Ferner Description An account of the resource The SARS-CoV-2 virus is the cause of the respiratory disease COVID-19. As of today, therapeutic interventions in severe COVID-19 cases are still not available as no effective therapeutics have been developed so far. Despite the ongoing development of a number of effective vaccines, therapeutics to fight the disease once it has been contracted will still be required. Promising targets for the development of antiviral agents against SARS-CoV-2 can be found in the viral RNA genome. The 5'- and 3'-genomic ends of the 30 kb SCoV-2 genome are highly conserved among Betacoronaviruses and contain structured RNA elements involved in the translation and replication of the viral genome. The 40 nucleotides (nt) long highly conserved stem-loop 4 (5_SL4) is located within the 5'-untranslated region (5'-UTR) important for viral replication. 5_SL4 features an extended stem structure disrupted by several pyrimidine mismatches and is capped by a pentaloop. Here, we report extensive 1H, 13C, 15N and 31P resonance assignments of 5_SL4 as the basis for in-depth structural and ligand screening studies by solution NMR spectroscopy. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource SARS-CoV-2, Covid19-NMR, Solution NMR-spectroscopy, RNA genome, 5′-UTR, 5_SL4 Identifier An unambiguous reference to the resource within a given context 10.1007/s12104-021-10026-7 Source A related resource from which the described resource is derived Biomolecular NMR assignments https://socictopen.socict.org/files/original/05e6f3855f65cd6a36f5872d3d845d7a.pdf 61653abef4fed8f93bcbbdc857e65736 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2-(3,4-Dihydro-4-Oxothieno[2,3-d]pyrimidin-2-ylthio) Acetamides as a New Class of Falcipain-2 Inhibitors. 3. Design, Synthesis and Biological Evaluation Creator An entity primarily responsible for making the resource Hualiang Jiang, Jian Li, Honglin Li, Jin Huang, Weiqiang Lu, Ruoqun Ma, Jie Liu, Jin Zhu, Tong Chen Description An account of the resource The cysteine protease falcipain-2 (FP-2) of Plasmodium falciparum is a principal cysteine protease and an essential hemoglobinase of erythrocytic P. falciparum trophozoites, making it become an attractive target enzyme for developing anti-malarial drugs. In this study, a series of novel small molecule FP-2 inhibitors have been designed and synthesized based on compound 1, which was identified by using structure-based virtual screening in conjunction with an enzyme inhibition assay. All compounds showed high inhibitory effect against FP-2 with IC50s of 1.46-11.38 μM, and the inhibitory activity of compound 2a was ~2 times greater than that of prototype compound 1. The preliminary SARs are summarized and should be helpful for future inhibitor design, and the novel scaffold presented here, with its potent inhibitory activity against FP-2, also has potential application in discovery of new anti-malarial drugs. Date A point or period of time associated with an event in the lifecycle of the resource 2009 Subject The topic of the resource 2-(3, 4-Dihydro-4-oxothieno[2, 3-d]pyrimidin-2-ylthio)acetamide derivatives, Falcipain-2 inhibitor, Malária, SAR Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/molecules14020785 Source A related resource from which the described resource is derived Molecules Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry Language A language of the resource EN https://socictopen.socict.org/files/original/33e354efba2eebf74e22b276bfcac8fa.pdf 6024ca09b52d66a38fc814754145f0c1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. Creator An entity primarily responsible for making the resource Kristy J Szretter, Brian P. Daniels, Hyelim Cho, Maria D Gainey, Wayne M. Yokoyama, Michael Gale, Herbert W. Virgin, Robyn S. Klein, Ganes C Sen, Michael S. Diamond Description An account of the resource Prior studies have shown that 2'-O methyltransferase activity of flaviviruses, coronaviruses, and poxviruses promotes viral evasion of Ifit1, an interferon-stimulated innate immune effector protein. Viruses lacking 2'-O methyltransferase activity exhibited attenuation in primary macrophages that was rescued in cells lacking Ifit1 gene expression. Here, we examined the role of Ifit1 in restricting pathogenesis in vivo of wild type WNV (WNV-WT) and a mutant in the NS5 gene (WNV-E218A) lacking 2'-O methylation of the 5' viral RNA cap. While deletion of Ifit1 had marginal effects on WNV-WT pathogenesis, WNV-E218A showed increased replication in peripheral tissues of Ifit1⁻/⁻ mice after subcutaneous infection, yet this failed to correlate with enhanced infection in the brain or lethality. In comparison, WNV-E218A was virulent after intracranial infection as judged by increased infection in different regions of the central nervous system (CNS) and a greater than 16,000-fold decrease in LD(50) values in Ifit1⁻/⁻ compared to wild type mice. Ex vivo infection experiments revealed cell-type specific differences in the ability of an Ifit1 deficiency to complement the replication defect of WNV-E218A. In particular, WNV-E218A infection was impaired in both wild type and Ifit1⁻/⁻ brain microvascular endothelial cells, which are believed to participate in blood-brain barrier (BBB) regulation of virus entry into the CNS. A deficiency of Ifit1 also was associated with increased neuronal death in vivo, which was both cell-intrinsic and mediated by immunopathogenic CD8⁺ T cells. Our results suggest that virulent strains of WNV have largely evaded the antiviral effects of Ifit1, and viral mutants lacking 2'-O methylation are controlled in vivo by Ifit1-dependent and -independent mechanisms in different cell types. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.ppat.1002698 Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy Language A language of the resource EN https://socictopen.socict.org/files/original/e0abbf72e1285d389466c7137cec44eb.pdf 6407a4703aa52ccd77153ababf583ed3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2014: Ano Internacional da Agricultura Familiar Creator An entity primarily responsible for making the resource Álvaro Simon Date A point or period of time associated with an event in the lifecycle of the resource 2020 Source A related resource from which the described resource is derived Revista Agropecuária Catarinense Publisher An entity responsible for making the resource available Empresa de Pesquisa Agropecuária e Extensão Rural de Santa Catarina - Epagri Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture (General) Relation A related resource <a href="https://publicacoes.epagri.sc.gov.br/RAC/article/view/788" target="_blank" rel="noreferrer noopener">https://publicacoes.epagri.sc.gov.br/RAC/article/view/788</a> https://socictopen.socict.org/files/original/1e90255d207d2db31ca06aa1cffa18ed.pdf 70b5b7801f6dbc466241a7a372e8b2eb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2015 MERS outbreak in Korea: hospital-to-hospital transmission Creator An entity primarily responsible for making the resource Moran Ki Description An account of the resource The distinct characteristic of the Middle East Respiratory Syndrome (MERS) outbreak in South Korea is that it not only involves intra-hospital transmission, but it also involves hospital-to-hospital transmission. It has been the largest MERS outbreak outside the Middle East, with 186 confirmed cases and, among them, 36 fatal cases as of July 26, 2015. All confirmed cases are suspected to be hospital-acquired infections except one case of household transmission and two cases still undergoing examination. The Korean health care system has been the major factor shaping the unique characteristics of the outbreak. Taking this as an opportunity, the Korean government should carefully assess the fundamental problems of the vulnerability to hospital infection and make short- as well as long-term plans for countermeasures. In addition, it is hoped that this journal, Epidemiology and Health, becomes a place where various topics regarding MERS can be discussed and shared. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Middle East respiratory syndrome coronavirus, Outbreak, Hospital infection, Epidemiology, statistics, Korea Identifier An unambiguous reference to the resource within a given context DOI: 10.4178/epih/e2015033 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN