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                  <text>Dominio científico: Coronavirus</text>
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                <text>A review of the impact of environmental factors on the fate and transport of coronaviruses in aqueous environments</text>
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                <text>Diplina Paul, Praveen Kolar, Steven G. Hall</text>
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                <text>Abstract The ongoing severe acute respiratory syndrome-coronavirus (SARS-CoV-2) has triggered the coronavirus pandemic (COVID-19) that has claimed hundreds of thousands of lives worldwide. This virus spreads predominantly by human-to-human transmission via respiratory droplets. However, the presence of this virus in the fecal and anal swabs of infected patients has triggered the need for research into its waterborne transmission. The various environmental factors that impact the persistence of coronavirus in different water matrices include temperature, UV exposure, organic matter, disinfectants as well as adversarial microorganisms. This review summarizes the most recent research data on the effect of various factors on coronavirus in aqueous environments. The available data suggest that: (i) increasing temperature decreases the overall persistence of the virus; (ii) the presence of organic matter can increase the survivability of coronavirus; (iii) chlorine is the most effective and economic disinfectant; (iv) membrane bioreactors in wastewater treatment plants are hosts of competitive microorganisms that can inactivate coronaviruses; (v) ultraviolet irradiation is another effective option for virus inactivation. However, the inactivation disinfection kinetics of coronaviruses are yet to be fully understood. Thus, further research is needed to understand its fate and transport with respect to the water cycle so that effective strategies can be adopted to curb its effects. These strategies may vary based on geographic, climatic, technical, and social conditions around the globe. This paper explores possible approaches and especially the conditions that local communities and authorities should consider to find optimal solutions that can limit the spread of this virus.</text>
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                <text>10.1038/s41545-020-00096-w</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Water supply for domestic and industrial purposes</text>
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                <text>A Review of the Strategies and Policies for the Prevention and Control of the COVID-19 at Workplaces</text>
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                <text>Farideh  Golbabaei, Saba Kalantari</text>
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                <text>The occupational settings present high risk in terms of exposure and spreading of the Corona Virus‑2019 (COVID-19) due to the gathering of many individuals. Although still uncertainty remains around COVID-19 and it is early to have conclusion on its prevention and control, different policies have been promoted by international organizations and health authorities regarding high risk staff to reduce exposure in occupational settings. The aim of this study was to provide a brief review of the required strategies and policies to prevent and control COVID-19 at workplaces. Because of the wide and rapid spread of new coronavirus globally, all people, including employees, and employers should implement the necessary instructions, training, and measures for the prevention and control of infection. Furthermore, governments and health organizations should promote prevention and control measures in three levels of engineering, administrative, and personal protective equipment (PPE) controls to prevent COVID-19 at workplaces.</text>
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                <text>2020</text>
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                <text>International Journal of Occupational Hygiene</text>
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                <text>Tehran University of Medical Sciences</text>
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                <text>Environmental technology. Sanitary engineering</text>
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                  <text>Agricultura sostenible</text>
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                <text>Giorgia Graells, Giorgia Graells, Giorgia Graells, Nao Nakamura, Juan L. Celis-Diez, Nelson A. Lagos, Nelson A. Lagos, Pablo A. Marquet, Pablo A. Marquet, Patricio Pliscoff, Stefan Gelcich, Stefan Gelcich, Stefan Gelcich</text>
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                <text>Coastal urban areas have dramatically increased during the last decades, however, coastal research integrating the impacts and challenges facing urban areas is still scarce. To examine research advances and critical gaps, a review of the literature on coastal urban ecology was performed. Articles were selected following a structured decision tree and data were classified into study disciplines, approaches, type of analysis, main research objectives, and Pickett's paradigms in-, of-, and for- the city, among other categories. From a total of 237 publications, results show that most of the research comes from the USA, China, and Australia, and has been carried out mostly in large cities with populations between 1 and 5 million people. Focus has been placed on ecological studies, spatial and quantitative analysis and pollution in coastal urban areas. Most of the studies on urban ecology in coastal zones were developed at nearshore terrestrial environments and only 22.36% included the marine ecosystem. Urban ecological studies in coastal areas have mainly been carried out under the paradigm in the city with a focus on the disciplines of biology and ecology. Results suggest a series of disciplinary, geographical, and approach biases which can present a number of risks. Foremost among these is a lack of knowledge on social dimensions which can impact on sustainability. A key risk relates to the fact that lessons and recommendations of research are mainly from developed countries and large cities which might have different institutional, planning and cultural settings compared to developing and mid-income countries. Scientific research on coastal urban areas needs to diversify toward an ecology of and for the cities, in order to support coastal development in a diversity of countries and settings.</text>
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                <text>2021</text>
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                <text>coastal cities, coastal urban ecology, coastal urbanization, marine urbanization, urban ecology paradigms</text>
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                <text>10.3389/fmars.2021.617897</text>
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                <text>Frontiers in Marine Science</text>
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                <text>Frontiers Media S.A.</text>
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                <text>A Review on Coronavirus Disease (COVID-19) and What is Known about it</text>
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                <text>Sara Taheri</text>
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                <text>Pandemic of New Coronavirus 2019 is becoming a health crisis in the world. The various aspects of the virus are still unknown. This study aims to introduce general aspects of the virus. This study is a narrative review that reviews the available literatures on the internet. Articles published from January 1, 2020 to March 3, 2020 were searched using the keywords COVID-19 and New Coronavirus 2019. The search was mainly conducted through PubMed and Google Scholar, using the keywords COVID-19 and New Coronavirus 2019. We also used Regular Google's search engine to gather news and background information. Prevalence, control, and prevention aspects of the disease were reviewed and presented. The study showed that the ways of transmitting the Covid 19 virus are through respiratory droplets and direct contact with the virus-containing secretions. The causes of the overwhelming prevalence of this disease can be attributed to its high incubation period and its transmission in the asymptomatic, mild, or pre-emergent periods. The study also found symptoms of the virus in people with chronic diseases such as cardiovascular disease, diabetes, cancer, hypertension and chronic respiratory illnesses, and the risk of the virus increases with age and a definite cure has not been discovered yet. The results showed that the epidemic of the new virus will continue for three months and can be prevented by the methods of prevention and management of the factors influencing its transmission. Suggested ways to treat the disease are also being investigated. Currently, the only way to control Coronavirus 19 is to maintain personal hygiene, boost immunity system of body and avoid staying in crowded places.</text>
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                <text>Taṣvīr-i salāmat</text>
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                <text>Tabriz University of Medical Sciences</text>
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                <text>Medicine (General)</text>
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                <text>A Review on Epidemiology, Emergence, Spread, Clinical Aspects, Avoidance and Management of COVID-19 Outbreak</text>
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            <name>Creator</name>
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            <elementTextContainer>
              <elementText elementTextId="49215">
                <text>Mahdi Mohammed Alrajhi, Naif Albaqami</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Background: COVID-19 or corona virus outbreak is a major source of disaster in the year 2020 which has distraught about 220 countries around the globe. The source of the outbreak was first identified in the province of Wuhan, China in December 2019. As of now, there are about 52,00,000 positive cases of the virus by the last week of May 2020 causing approx. 3,42,000 deaths worldwide.Methods: The objective of this review paper is to methodically analyze the reasons, findings, deterrence, and control of this virus. The secondary sources applied in this analysis have been taken from the data and information available on a public domain.Results: Testing in a laboratory for the identification of the virus comprises of the usual or decreased counts of white cells with lofty protein C-reactive. The tomographic chest scan is typically anomalous yet in patients having no indications. Preclusion in this deadly ailment include entails isolation of suspected numbers. Strict precautionary measures are required with suspects.Conclusion: This paper attempts to review the structure, cause of infection, direction of diffusion, pathogenesis, quantifiable attributes, management, and avoidance of virus.</text>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
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                <text>management, Symptoms, deterrence, substantiations covid-19</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="49219">
                <text>Journal of Research in Medical and Dental Science</text>
              </elementText>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Amber Publication</text>
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            <elementTextContainer>
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                <text>Medicine (General), Dentistry</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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                <text>A Review on Novel Drug Targets and Future Directions for COVID-19 Treatment</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="62985">
                <text>Wondmkun YT, Mohammed OA</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Yohannes Tsegyie Wondmkun,1 Ousman Ahmed Mohammed2 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2College of Health Sciences, Woldia University, Woldia, EthiopiaCorrespondence: Yohannes Tsegyie WondmkunDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Churchill Avenue, P.O. Box 1176, Addis Ababa, EthiopiaEmail yohannes.tsegyie@aau.edu.etAbstract: Severe acute respiratory syndrome coronavirus-2 causes coronavirus disease-19 (COVID-19) that spreads quickly in the world. Considering the impact of this pandemic, researchers have been racing to understand the peculiar nature of the virus and the pathogenesis of the disease to uncover possible drug targets, effective therapeutic agents, and vaccines. Accordingly, numerous drug targets are identified by scientists. Among them, structural glycoproteins, virulence factors, host-specific receptors and enzymes, non-structure proteins, the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway, and pro-inflammatory cytokines are discussed herein. This review summarizes the promising drug targets for COVID-19, and highlights antiviral strategies which depend on molecular interactions between viral small molecules and host biologic machinery for repurposing the available clinical drugs. In addition, it gives a strong rational basis for the ongoing discovery of new drugs and vaccines.Keywords: COVID-19, drug targets, SARS-COV-2, non-structural proteins, structural proteins</text>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="62988">
                <text>covid-19, SARS-CoV-2, non-structural proteins, structural proteins, Drug targets</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="62989">
                <text>Biologics : Targets &amp; Therapy</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="62990">
                <text>Dove Medical Press</text>
              </elementText>
            </elementTextContainer>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="50218">
                <text>A Review on Recent Guidelines and Articles about Prevention of Covid-19 Infection in Dental Settings</text>
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            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50219">
                <text>Ehsan Rafeemanesh, Fatemeh Ahmadi, Taraneh Movahhed, Orang Abdollahi</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="50220">
                <text>Introduction: Dental services are high-risk centers to spread the new coronavirus disease 2019 (COVID-19) due to the type of treatment and closeness of the staff to patients. For this reason, several guidelines have been developed by international organizations regarding the necessity for complying with health standards in these centers. The present study aimed to review the guidelines and studies conducted on the prevention and control of COVID-19 in dental settings. Materials and Methods: The current study was carried out to investigate COVID-19 prevention and control strategies in dental settings. Several databases, including Google Scholar, PubMed, and Scopus, since 2019 to 2020 in addition to the guidelines of the Centers for Disease Control and Prevention, Occupational Safety and Health Administration, National Health Service, and American Dental Association were reviewed through subject searching and used in the present study. Results: Studies have shown that the staff of dental centers similar to other health care workers is at high risk of getting COVID-19. The majority of published guidelines have emphasized the elimination of nonemergency measures and provision of remote counseling services to patients. In case of the need for an emergency visit, it is necessary to implement preventive measures, especially hand hygiene and protection measures, to prevent the spread of the virus through aerosol transmission. Conclusion: Due to the increasing prevalence of COVID-19, it is necessary to provide all dental staff with the essential information and training on prevention and control strategies based on scientific guidelines and standards. This issue can play an important role in reducing the number of patients and preventing the spread of the virus in the community.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50221">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50222">
                <text>control, Prevention, covid-19, Dentistry</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="50223">
                <text>10.22038/jmds.2020.48058.1907</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="50224">
                <text>Journal of Mashhad Dental School</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="50225">
                <text>Mashhad University of Medical Sciences</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="50226">
                <text>Medicine, Dentistry</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
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            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50558">
                <text>A Review on Remdesivir: A Possible Promising Agent for the Treatment of COVID-19</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50559">
                <text>Hashemian SM, Farhadi T, Velayati AA</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="50560">
                <text>Seyed MohammadReza Hashemian,1,2 Tayebeh Farhadi,2 Ali Akbar Velayati2 1Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran; 2Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, IranCorrespondence: Tayebeh FarhadiChronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, IranTel/ Fax +982126109931Email tayebehfarhadi@yahoo.comAbstract: The novel coronavirus 2019 (2019-nCoV), formally named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel human infectious coronavirus. The disease caused by SARS-CoV-2 is named COVID-19. Development and manufacturing of specific therapeutics and vaccines to treat COVID-19 are time-consuming processes. At this time, using available conventional therapeutics along with other treatment options may be useful to fight COVID-19. In different clinical trials, efficacy of remdesivir (GS-5734) against Ebola virus has been demonstrated. Moreover, remdesivir may be an effective therapy in vitro and in animal models infected by SARS and MERS coronaviruses. Hence, the drug may be theoretically effective against SARS-CoV-2. Remdesivir is a phosphoramidate prodrug of an adenosine C-nucleoside. By entrance into respiratory epithelial cells in human, the prodrug is metabolized to a nucleoside triphosphate as the active form. The nucleoside analog inhibits the viral RNA-dependent RNA polymerase (RdRp) by competing with the usual counterpart adenosine triphosphate (ATP). The nucleoside analog is incorporated into the generating RNA strand and causes a delayed stop in the viral replication process. Knowledge about the potential efficacy of remdesivir against coronaviruses has been restricted to in vitro studies and animal models. However, information related to COVID-19 is rapidly growing. Several clinical trials are ongoing for the management of COVID-19 using remdesivir. In this study, characteristics of remdesivir and its usage for treatment of COVID-19 are reviewed based on an electronic search using PubMed and Google Scholar.Keywords: remdesivir, COVID-19, SARS-CoV-2, RNA-dependent RNA polymerase</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50561">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="50562">
                <text>covid-19, SARS-CoV-2, Remdesivir, RNA dependent RNA polymerase</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="50563">
                <text>Biotemas</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="50564">
                <text>Universidade Federal de Santa Catarina</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="50565">
                <text>Therapeutics. Pharmacology</text>
              </elementText>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
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                <text>A Review on SARS-CoV-2 Virology, Pathophysiology, Animal Models, and Anti-Viral Interventions</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="47842">
                <text>Sabari  Nath Neerukonda, Upendra Katneni</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="47843">
                <text>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of CoV disease 2019 (COVID-19) is a highly pathogenic and transmissible CoV that is presently plaguing the global human population and economy. No proven effective antiviral therapy or vaccine currently exists, and supportive care remains to be the cornerstone treatment. Through previous lessons learned from SARS-CoV-1 and MERS-CoV studies, scientific groups worldwide have rapidly expanded the knowledge pertaining to SARS-CoV-2 virology that includes in vitro and in vivo models for testing of antiviral therapies and randomized clinical trials. In the present narrative, we review SARS-CoV-2 virology, clinical features, pathophysiology, and animal models with a specific focus on the antiviral and adjunctive therapies currently being tested or that require testing in animal models and randomized clinical trials.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="47844">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="47845">
                <text>Animal Models, covid-19, SARS-CoV-2, antivirals</text>
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            </elementTextContainer>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="47846">
                <text>10.3390/pathogens9060426</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="47847">
                <text>Biotemas</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Medicine</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A Review on the Novel Coronavirus Disease based on In-silico Analysis of Various Drugs and Target Proteins</text>
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                <text>Hetalkumar Panchal, Hiren A. Dhameliya, Gauravi N. Trivedi, Janhavi T. Karlekar</text>
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                <text>Coronavirus Disease (COVID-19) is a new disease that emerged in Wuhan, China which spreads throughclose contact of people, often by small droplets produced during coughing or sneezing. Detail mechanismby which it spreads between people are under investigation. The World Health Organization (WHO)declared this disease as a pandemic after the severity of the disease increased. Many scientific reportsgathered have suggested many drugs that could be potential candidates for the treatment. Although,clinical effectiveness has not been fully evaluated. In this review, we have aggregated the data fromfew research articles, official news websites and few review papers regarding its phylogenetic relation,genomic constitution, transmission, replication and in-silico analysis done by researchers for fewpotent drugs that are currently used to cure COVID-19. SARS-CoV-2 belongs to Betacoronavirus genuswith Genome structure consists 14 Open Reading Frames (ORFs) that encode 27 proteins. Coronavirusreplicates into the host cells having unique mechanisms like ribosome frame-shifting and synthesisof genomic and sub genomic RNAs. In-silico methods have the advantage that they can make fastpredictions for a large set of compounds in a high-throughput mode and also make their predictionbased on the structure of a compound even before it has been synthesized. In-silico softwares havebeen used to find or to improve a novel bioactive compound, which may exhibit a strong affinity to aparticular target in the drug development process.</text>
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                <text>2020</text>
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                <text>Pandemic, WHO, MERS-CoV, SARS-CoV, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.22207/JPAM.14.SPL1.22</text>
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                <text>Journal of Pure and Applied Microbiology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="37413">
                <text>Journal of Pure and Applied Microbiology</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Microbiology</text>
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