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                <text>Guan-Min Jiang, Xiaoxue Chen, Sisi Kang, Mei Yang, Suhua He, Yueming Wang, Yao-Qing Chen, Zhongsi Hong, Jing Liu, Qiuyue Chen, Ziliang Zhou, Zhechong Zhou, Zhaoxia Huang, Xi Huang, Huanhuan He, Weihong Zheng, Hua-Xin Liao, Fei Xiao, Hong Shan, Shoudeng Chen</text>
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                <text>While SARS-CoV-2 S protein targeting monoclonal antibodies (mAbs) are well studied, little is known about N protein-targeting mAbs. Here, Kang et al. provide the crystal structure of the N protein RNA binding domain with a mAb derived from a convalescent patient and show that it compromises the N protein-induced complement hyperactivation.</text>
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                <text>This study is a scoping review of the literature on organizational adaptation in school settings during the early stages of the COVID-19 pandemic. Dramatic and unexpected environmental changes raise questions about the capacity of schooling organizations to adapt to in response to the pandemic. Different management practices have implications for the selection of organizational behaviors, electively in school settings. The research literature on school responses is analyzed from a selectionist perspective. The aim of this study is to identify and describe three constituting elements of this perspective: variation, interaction, and selection. An additional element is considered in this analysis and comprises the mechanisms of exploration and exploitation in the context of organizational adaptation. Sixteen studies met the selection criteria of describing emergent processes in schools. The findings highlight the emergence of exploration, as teachers actively experimented with a range of strategies and methods in order to maintain educational activities in the complex and uncertain context of the COVID-19 pandemic. However, several questions are raised regarding the effects and maintenance of new practices in the post-pandemic scenario. Management practices that facilitate variation and open communication about learning processes can contribute to the process of organizational adaptation.</text>
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                <text>O Semiárido de Minas Gerais conviveu com forte seca entre 2011 e 2018. Nessa área de mananciais já degradados, precipitações escassas e concentradas contribuíram para reduzir a água para uso doméstico e produtivo. Tomando a grande seca como cenário, este artigo busca compreender a dinâmica cotidiana de abastecimento das famílias rurais e analisar os arranjos feitos para assegurar provisão de água em duas comunidades de agricultores familiares do gerais, os vastos chapadões do Alto-Médio rio São Francisco. Investigou o tema usando técnicas de pesquisa social (entrevistas e grupos focais) e ambiental (dimensionamento de oferta e consumo de água) durante as estações de estiagem e de chuvas ao longo de um ano. Este artigo revela que, nessa “quadra de seca”, a existência de programas públicos para provimento de água e renda assegurou abastecimento suficiente para a população rural. No entanto, os agricultores precisaram introduzir ajustes e inovações na gestão da água, no consumo e, principalmente, na agricultura, para conservar, mesmo que em novas bases, os sistemas de produção e a organização comunitária.</text>
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                <text>&lt;a href="https://revistaesa.com/ojs/index.php/esa/article/view/esa28-3_09_seca" target="_blank" rel="noreferrer noopener"&gt;https://revistaesa.com/ojs/index.php/esa/article/view/esa28-3_09_seca&lt;/a&gt;</text>
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                <text>Abstract Background Single Nucleotide Polymorphism (SNP) in the genome has become crucial information for clinical use. For example, the targeted cancer therapy is primarily based on the information which clinically important SNPs are detectable from the tumor. Many hospitals have developed their own panels that include clinically important SNPs. The genome information exchange between the patient and the hospital has become more popular. However, the genome sequence information is innate and irreversible and thus its leakage has serious consequences. Therefore, protecting one’s genome information is critical. On the other side, hospitals may need to protect their own panels. There is no known secure SNP panel scheme to protect both. Results In this paper, we propose a secure SNP panel scheme using homomorphically encrypted K-mers without requiring SNP calling on the user side and without revealing the panel information to the user. Use of the powerful homomorphic encryption technique is desirable, but there is no known algorithm to efficiently align two homomorphically encrypted sequences. Thus, we designed and implemented a novel secure SNP panel scheme utilizing the computationally feasible equality test on two homomorphically encrypted K-mers. To make the scheme work correctly, in addition to SNPs in the panel, sequence variations at the population level should be addressed. We designed a concept of Point Deviation Tolerance (PDT) level to address the false positives and false negatives. Using the TCGA BRCA dataset, we demonstrated that our scheme works at the level of over a hundred thousand somatic mutations. In addition, we provide a computational guideline for the panel design, including the size of K-mer and the number of SNPs. Conclusions The proposed method is the first of its kind to protect both the user’s sequence and the hospital’s panel information using the powerful homomorphic encryption scheme. We demonstrated that the scheme works with a simulated dataset and the TCGA BRCA dataset. In this study, we have shown only the feasibility of the proposed scheme and much more efforts should be done to make the scheme usable for clinical use.</text>
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                <text>2019</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="14667">
                <text>SNP panel, Homomorphic encryption, k-mer, Genomic security, Genomic privacy</text>
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            <name>Identifier</name>
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                <text>DOI: 10.1186/s12864-019-5473-z</text>
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          <element elementId="48">
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              <elementText elementTextId="14669">
                <text>BMC Genomics</text>
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                <text>BMC</text>
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                <text>Genetics, Biotechnology</text>
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                <text>EN</text>
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                  <text>Agricultura sostenible</text>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>A Seguridade Social rural como um seguro agrícola: alcances previstos e imprevistos de uma política pública no sul do Brasil</text>
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                <text>Nádia Velleda Caldas, Flávio Sacco dos Anjos</text>
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            <description>An account of the resource</description>
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                <text>O artigo analisa a importância da previdência social rural na dinâmica da agricultura familiar no Sul do Brasil. Os resultados indicam que as aposentadorias e pensões são decisivas na perspectiva de redução das desigualdades. Foi comprovada a hipótese de que estes recursos servem para o financiamento das atividades agropecuárias em uma proporção considerável (53%) dos estabelecimentos familiares. Abstract The article analyzes the importance of rural social welfare in family farming. The results show that the pensions are essentially important under the perspective of reducing inequalities. The hypothesis that these resources are equally important to finance farm and cattle raising activities was confirmed under a considerable proportion (53%) in the family farms as a whole.</text>
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              <elementText elementTextId="142714">
                <text>20th-21st Centuries, Agricultura Familiar, Brasil, Brazil, Family farming, Políticas Públicas, Previdência social rural, Public policies, Social rural security, Séculos xx-xxi</text>
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                <text>10.18441/ibam.9.2009.36.57-78</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Iberoamericana. América Latina - España - Portugal</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="142717">
                <text>Iberoamericana / Vervuert</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="142718">
                <text>Social Sciences, Latin America. Spanish America, French literature - Italian literature - Spanish literature - Portuguese literature, History of Portugal, History of Spain</text>
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                <text>&lt;a href="http://journals.iai.spk-berlin.de/index.php/iberoamericana/article/view/733" target="_blank" rel="noreferrer noopener"&gt;http://journals.iai.spk-berlin.de/index.php/iberoamericana/article/view/733&lt;/a&gt;</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>A seq2seq model to forecast the COVID-19 cases, deaths and reproductive R numbers in US counties.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="78068">
                <text>Stephen V Faraone, Yanli Zhang-James, Jonathan Hess, Asif Salekin, Dongliang Wang, Samuel Chen, Peter Winkelstein, Christopher P Morley</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="78069">
                <text>The global pandemic of coronavirus disease 2019 (COVID-19) has killed almost two million people worldwide and over 400 thousand in the United States (US). As the pandemic evolves, informed policy-making and strategic resource allocation relies on accurate forecasts. To predict the spread of the virus within US counties, we curated an array of county-level demographic and COVID-19-relevant health risk factors. In combination with the county-level case and death numbers curated by John Hopkins university, we developed a forecasting model using deep learning (DL). We implemented an autoencoder-based Seq2Seq model with gated recurrent units (GRUs) in the deep recurrent layers. We trained the model to predict future incident cases, deaths and the reproductive number, R . For most counties, it makes accurate predictions of new incident cases, deaths and R values, up to 30 days in the future. Our framework can also be used to predict other targets that are useful indices for policymaking, for example hospitalization or the occupancy of intensive care units. Our DL framework is publicly available on GitHub and can be adapted for other indices of the COVID-19 spread. We hope that our forecasts and model can help local governments in the continued fight against COVID-19.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2021</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="78071">
                <text>10.1101/2021.04.14.21255507</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="78072">
                <text>medRxiv : the preprint server for health sciences</text>
              </elementText>
            </elementTextContainer>
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          <name>Dublin Core</name>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <name>Title</name>
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                <text>A Severe Acute Respiratory Syndrome extranet: supporting local communication and information dissemination</text>
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            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="28288">
                <text>Thomas Helen, Akhtar-Danesh Noori, Kealey Cathy M, Valaitis Ruta K, Brunetti Glenn M</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="28289">
                <text>Abstract Background The objective of this study was to explore the use and perceptions of a local Severe Acute Respiratory Syndrome (SARS) Extranet and its potential to support future information and communication applications. The SARS Extranet was a single, managed electronic and limited access system to manage local, provincial and other SARS control information. Methods During July, 2003, a web-based and paper-based survey was conducted with 53 SARS Steering Committee members in Hamilton. It assessed the use and perceptions of the Extranet that had been built to support the committee during the SARS outbreak. Before distribution, the survey was user-tested based on a think-aloud protocol, and revisions were made. Quantitative and qualitative questions were asked related to frequency of use of the Extranet, perceived overall usefulness of the resource, rationale for use, potential barriers, strengths and limitations, and potential future uses of the Extranet. Results The response rate was 69.4% (n = 34). Of all respondents, 30 (88.2%) reported that they had visited the site, and rated it highly overall (mean = 4.0; 1 = low to 5 = high). However, the site was rated 3.4 compared with other communications strategies used during the outbreak. Almost half of all respondents (44.1%) visited the site at least once every few days. The two most common reasons the 30 respondents visited the Extranet were to access SARS Steering Committee minutes (63.3%) and to access Hamilton medical advisories (53.3%). The most commonly cited potential future uses for the Extranet were the sending of private emails to public health experts (63.3%), and surveillance (63.3%). No one encountered personal barriers in his or her use of the site, but several mentioned that time and duplication of email information were challenges. Conclusion Despite higher rankings of various communication strategies during the SARS outbreak, such as email, meetings, teleconferences, and other web sites, users generally perceived a local Extranet as a useful support for the dissemination of local information during public health emergencies.</text>
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            <name>Date</name>
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              <elementText elementTextId="28290">
                <text>2005</text>
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              <elementText elementTextId="28291">
                <text>DOI: 10.1186/1472-6947-5-17</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="28292">
                <text>BMC Medical Informatics and Decision Making</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="28293">
                <text>BMC</text>
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            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="28294">
                <text>Computer applications to medicine. Medical informatics</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>A significance do Aquisição Food Programme (PAA) gives us Territórios cidadania two states of Minas Gerais and Bahia: Creation of markets from novos da visão two Assistência Agents Technique and Extensão Rural (ATER)</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="144765">
                <text>Nora Beatriz Presno Amodeo, Telma Coelho Silva, Palloma Rosa Ferreira</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="144766">
                <text>This article aims to identify how the Foodstuff Acquisition Program has influenced market creation for family farmers in two Brazilian states – Minas Gerais e Bahia and also the limitations and benefits of the program from the point of view of the extension agents. A bibliographic research and a quantitative exploratory study were conducted, questionnaires were sent to extension agents who work for public rural extension agencies, municipalities, NGOs, cooperatives and producers’ associations, during the year 2010-2011</text>
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            <name>Date</name>
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                <text>2014</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="144768">
                <text>Agricultura Familiar, Programa de Aquisição de Alimentos, mercado</text>
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            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="144769">
                <text>Mundo Agrario</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="144770">
                <text>Universidad Nacional de La Plata</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="144771">
                <text>Social history and conditions. Social problems. Social reform, Sociology (General)</text>
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            <name>Relation</name>
            <description>A related resource</description>
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                <text>&lt;a href="http://www.mundoagrario.unlp.edu.ar/article/view/5316" target="_blank" rel="noreferrer noopener"&gt;http://www.mundoagrario.unlp.edu.ar/article/view/5316&lt;/a&gt;</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study</text>
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                <text>Jin Yongjie, Cheung Jo LK, Chiu Rossa WK, Chung Grace TY, Chim Stephen SC, Chan Paul KS, Lo YM Dennis</text>
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                <text>Abstract Background The Severe Acute Respiratory Syndrome (SARS) was a newly emerged infectious disease which caused a global epidemic in 2002–2003. Sequence analysis of SARS-coronavirus isolates revealed that specific genotypes predominated at different periods of the epidemic. This information can be used as a footprint for tracing the epidemiology of infections and monitor viral evolution. However, direct sequencing analysis of a large number of clinical samples is cumbersome and time consuming. We present here a simple and rapid assay for the screening of SARS-coronavirus genotypes based on the use of fluorogenic oligonucleotide probes for allelic discrimination. Methods Thirty SARS patients were recruited. Allelic discrimination assays were developed based on the use of fluorogenic oligonucleotide probes (TaqMan). Genotyping of the SARS-coronavirus isolates obtained from these patients were carried out by the allelic discrimination assays and confirmed by direct sequencing. Results Genotyping based on the allelic discrimination assays were fully concordant with direct sequencing. All of the 30 SARS-coronavirus genotypes studied were characteristic of genotypes previously documented to be associated with the latter part of the epidemic. Seven of the isolates contained a previously reported major deletion but in patients not epidemiologically related to the previously studied cohort. Conclusion We have developed a simple and accurate method for the characterization and screening of SARS-coronavirus genotypes. It is a promising tool for the study of epidemiological relationships between documented cases during an outbreak.</text>
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                <text>2005</text>
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                <text>DOI: 10.1186/1471-2334-5-87</text>
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                <text>BMC Infectious Diseases</text>
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                <text>BMC</text>
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              <elementText elementTextId="21318">
                <text>Infectious and parasitic diseases</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>EN</text>
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