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                  <text>Dominio científico: Coronavirus</text>
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                <text>SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges</text>
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                <text>Ali Hekmatnia, Rajender S. Varma, Parisa Iravani, Mahmoud Nasrollahzadeh, Salman Fallah, Mohaddeseh Sajjadi, Siavash Iravani, Ghazaleh  Jamalipour Soufi, Nasrin Shafiei</text>
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                <text>SARS-CoV-2 (COVID-19) has today multiplied globally and various governments are attempting to stop the outbreak of the disease escalation into a worldwide health crisis. At this juncture, readiness, candor, clarity, and partaking of data are of paramount importance to speed up factual evaluation and starting pattern control activities, including serendipitous findings. Owing to the involvement of COVID-19, many facts regarding virulence, pathogenesis, and the real viral infection source and/or transmission mode still need to be addressed. The infected patients often present clinical symptoms with fever, dyspnea, fatigue, diarrhea, vomiting, and dry cough, as well as pulmonary, infiltrates on imaging. Extensive measures to decrease person-to-person transmission of COVID-19 are being implemented to prevent, recognize, and control the current outbreak as it is very similar to SARS-CoV in its clinical spectrum, epidemiology, and pathogenicity. In response to this fatal disease and disruptive outbreak, it is extremely vital to expedite the drug development process to treat the disease and vaccines for the prevention of COVID-19 that would help us defeat this pandemic expeditiously. This paper sums up and unifies the study of virological aspects, disease transmission, clinically administered techniques, therapeutics options, managements, future directions, designing of vaccines, and news dissemination pertaining to COVID-19.</text>
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                <text>diagnosis, cardiovascular systems, SARS-CoV-2, COVID-19, therapeutics options, respiratory systems</text>
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                <text>DOI: 10.3390/app10103641</text>
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                <text>Applied Sciences</text>
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                <text>MDPI AG</text>
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                <text>Biology (General), Technology, Physics, Chemistry, Engineering (General). Civil engineering (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting</text>
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                <text>Ali Hosseini Rad SM, Alexander  D. McLellan</text>
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            <description>An account of the resource</description>
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                <text>The SARS-CoV-2 virus is a recently-emerged zoonotic pathogen already well adapted to transmission and replication in humans. Although the mutation rate is limited, recently introduced mutations in SARS-CoV-2 have the potential to alter viral fitness. In addition to amino acid changes, mutations could affect RNA secondary structure critical to viral life cycle, or interfere with sequences targeted by host miRNAs. We have analysed subsets of genomes from SARS-CoV-2 isolates from around the globe and show that several mutations introduce changes in Watson–Crick pairing, with resultant changes in predicted secondary structure. Filtering to targets matching miRNAs expressed in SARS-CoV-2-permissive host cells, we identified ten separate target sequences in the SARS-CoV-2 genome; three of these targets have been lost through conserved mutations. A genomic site targeted by the highly abundant miR-197-5p, overexpressed in patients with cardiovascular disease, is lost by a conserved mutation. Our results are compatible with a model that SARS-CoV-2 replication within the human host is constrained by host miRNA defences. The impact of these and further mutations on secondary structures, miRNA targets or potential splice sites offers a new context in which to view future SARS-CoV-2 evolution, and a potential platform for engineering conditional attenuation to vaccine development, as well as providing a better understanding of viral tropism and pathogenesis.</text>
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                <text>2020</text>
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                <text>SARS-CoV-2, miRNA, RNA secondary structure, conserved mutation</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.3390/ijms21134807</text>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Korean Society of Epidemiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Biology (General), Chemistry</text>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Spectrum of Chest Computed Tomography findings of Novel Coronavirus disease 2019 in Medical City in Baghdad, a case series</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Ali Ibrahim, Salam Joori, Atheer Adnan, Zaid Hammoodi, Haider Ghayad</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Background: Native chest Computed Tomography (CT) is a quick, non-invasive and practical investigation &amp; plays an important role in evaluation of Coronavirus Disease 2019.  Objective: to describe the chest CT findings in patients with confirmed coronavirus disease 2019 (COVID-19) in sample from Baghdad population.  Patients &amp; methods: Study sample consisted of 55 patients with laboratory confirmed COVID-19 from 1st March through 15th April 2020. Native chest CT was performed in radiology departments in Medical City Teaching Complex (MCTH). The chest CT images were reviewed &amp; analyzed.  Results: The most frequent CT findings were ground-glass opacities (47.3%) &amp; mixed ground glass &amp; consolidation (43.6%). Most lesions were multiple (67.2%), peripheral (56.3%) &amp; bilateral (81.8%). Least common findings were pleural effusion (7.2%) &amp; mediastinal lymphadenopathy (1.8%).  Conclusion: The commonest chest CT findings of COVID-19 in Baghdad population were multiple, bilateral, peripheral ground glass opacity &amp; consolidation.   </text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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                <text>Baghdad, Chest CT, MCTH, Keywords: COVID 19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.32007/jfacmedbagdad.621,21744</text>
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                <text>مجلة كلية الطب</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Faculty of Medicine University of Baghdad</text>
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                <text>Medicine (General), Medicine</text>
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              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Políticas para el espacio público en las ciudades europeas.</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Ali Madanipour, Sabine Knierbein, Aglaée Degros</text>
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            <description>An account of the resource</description>
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                <text>Las ciudades europeas están cambiando rápidamente en respuesta parcial a los procesos de integración europea, la migración internacional, la globalización económica y el cambio climático. Los espacios públicos de estas ciudades, como ingredientes esenciales de la imagen urbana y la experiencia, juegan un papel cada vez más importante en esta transición. Una cuestión clave se refiere al papel que los espacios públicos deben desempeñar en la transformación política, económica y cultural de las ciudades, y el impacto de estas transformaciones en la naturaleza del espacio público como un recurso compartido. ¿Cómo hacen las autoridades públicas para abordar al espacio público como un catalizador para el cambio y como un bien común? Vamos a esbozar los desafíos que enfrentan las ciudades europeas y la importancia del espacio público para hacer frente a estos desafíos. Sobre la base de estudios de casos de todo Europa (Amberes, Belfast, Berlín, Budapest, Dresde, Estambul, Londres, Milán, Nápoles, París, Viena, Varsovia, y seis ciudades de Suiza), diversos autores han analizado las formas en que los espacios públicos han sido abordados por los poderes públicos en su interacción con las sociedades urbanas. Exploramos la política del espacio público en tres partes: las estrategias, planes y políticas; múltiples funciones del espacio público, y la vida cotidiana en la ciudad. Vamos a describir los principales desafíos y examinar las respuestas de estas ciudades europeas, en busca de tendencias y patrones identificables.</text>
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                <text>2014</text>
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                <text>Diversidad cultural, Inclusión social, Resurgimiento económico, gobernabilidad urbana, protección ambiental</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Gestión y Ambiente</text>
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                <text>Universidad Nacional de Colombia</text>
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                <text>Geography. Anthropology. Recreation, Environmental sciences</text>
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                <text>&lt;a href="https://revistas.unal.edu.co/index.php/gestion/article/view/41216" target="_blank" rel="noreferrer noopener"&gt;https://revistas.unal.edu.co/index.php/gestion/article/view/41216&lt;/a&gt;</text>
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                <text>Will the Pandemic Crisis Covid-19 be a Turning Point in Changing and Bringing a New World Order?</text>
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                <text>Ali Madouni</text>
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                <text>Abstract. As the new pandemic broke out in almost the globe, part of analysts, observers and politicians hurried to talk early about the major changes that may be caused by the new spreading pandemic in all domains ; specifically at the political and economic fields, locally and internationally ; in an attempt to bring to the surface a profound perspective on the new world transformations and division. The present article main aim is to approach and investigate the global situation before, during and after the pandemic crisis of 2019 ; in all world continents, from the WWI until the Post Cold War era, not only that, but also to determine the pandemic crisis’s effects and consequences in all sectors as well as on the international actors of the international relations , additionally ; to its impacts on some core concepts in Politics. Through this inductive paper we ; also present an extrapolation of the current world situation in the light of new-traditional struggle between the two great powers in the world : China and the United States ; beside the sweeping explanations of the pandemic outbreak through some theories.</text>
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                <text>2020</text>
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                <text>globalization, economic crisis, Conspiracy theories, National Security, International Actors, The New World Order, pandemic outbreak 2019, sino-american competition</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Social sciences (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>The Organizational Creativity and its Relationship to Crisis Management in the Light of Coronavirus Pandemic</text>
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                <text>Ali Madouni</text>
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                <text>This paper aims to highlight the organizational creativity and how to manage crises, within the global pandemic crisis of 2019. Common that creativity and innovation are considered as core principles for the continuous advance of any organizational structure, through investment in ideas and manners; to modernize and cope with sorts of response to the performant and technological progress and changes, and to increase the competition effectiveness of the organizational structure, correspondingly. In the other hand, as it is typically recognized that any organization is affected by the external changes, conditions and occurrences; in positive or negative sides. Additionally, the essential pillars of such entities lie implicitly in the strong policies and strategies in dealing with such situations, and in maintaining its balance, especially in time of crises, in particular domestic domains, or crises of a global span. Through this presented paper, we target to approach the relationship between the organizational creativity and crisis management in linkage to the current global pandemic crisis ; as we extend the affecting features on the organizational structure creativity, and its communicative activities.  </text>
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                <text>2020</text>
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                <text>coronavirus 2019, crisis management, communication activities, Organizational Creativity, impact features</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Social sciences (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Mersin İlinde Gerçekleşen İntihar Olgularının Sosyodemoğrafik Özellikleri</text>
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                <text>Ali Metin, Günay Çileli, İlker Koçar, Halis Dokgöz</text>
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            <description>An account of the resource</description>
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                <text>İntihar, toplumsal dayanışma, bağımlılık ve özerklik ilişkisindeki dengesizliğin bir sonucu olarak ortaya çıkabilmekte ve toplumsal bağların gücüne, yapısına göre değişiklik gösterebilmektedir. Bireylerin toplumla ilişkileri, toplumsal destek türü intihar eğilimini  etkilemektedir.  Mersin ilinde 2012 ve 2013 yılları arasında intihar orijinli meydana gelen ölüm olgularının sosyodemografik özelliklerinin belirlenmesi amacıyla yapılan bu çalışmada; 30 olgunun en küçüğü 15 yaşında kız çocuğu, en büyüğü 80 yaşında kadın olup, yaş ortalaması 38.46 yıldır. Olguların 17’si (% 56,7) erkek, 11’i (% 36,6) evli, 16’sı (% 53,4) bekardır. 11 olgu (% 36,6) ilaç ve benzeri madde alımını, yedisi (% 23,3) ası yöntemini, beşi (% 16,6) yüksekten düşme yöntemini uyguladığı, 11 olgunun (% 36,6) kış ve sekizinin (% 26,6) sonbahar mevsiminde intihar eylemini gerçekleştirmiş olduğu, dört (% 13,33) olguda daha önce intihar girişimi öyküsünün bulunduğu, yedi (% 23,33) olguda daha önce psikiyatrik rahatsızlık nedeni ile tedavi gördüğünün ifade edildiği tespit edilmiştir.  İntihara yönelik olarak sosyolojik, biyolojik ve psikolojik yaklaşımlar, intihar eyleminin karmaşıklığını ortaya koymaktadır. Bu çalışmada Mersin ilinde intihar orijinli meydana gelen ölüm olgularının sosyodemografik özelliklerinin belirlenmesi amaçlanmıştır.   Anahtar kelimeler: İntihar, otopsi, adli tıp, sosyodemografik özellikler, ölüm.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2014</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>İntihar, otopsi, adli tıp, sosyodemografik özellikler, Ölüm</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.17986/blm.2014191769</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Adli Tıp Bülteni</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Adli Tıp Uzmanları Derneği</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
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                <text>EN, TR</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Bakımevinde Ölüm ile Sonuçlanan Engelli Çocuğa Yönelik Fiziksel İstismar Olgusu</text>
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                <text>Ali Metin, Nursel Gamsız Bilgin, Veli Yıldırım</text>
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                <text>Engelliler toplumumuzun yaklaşık %12.3 gibi büyük bir bölümünü oluşturmaktadır. Engelli bireyler, şiddet açısından risk grubunda bulunmaktadır. Engelliler çocuklar, kadınlar, yaşlılar gibi fiziksel, cinsel, ekonomik, duygusal şiddettin hedefi olmaktadır. Yaşanan şiddetin sonucunda fiziksel ve ruhsal sorunlar yaşamakta, engel durumları artmakta veya yaşamlarını yitirebilmektedirler. Yapılan ulusal ve uluslararası birçok çalışmada engellilerin fiziksel ve cinsel başta olmak üzere birçok şiddet türüne maruz kaldıkları vurgulanmaktadır 9 yaşında bakımevinde kalan olgumuzda bakımından sorumlu kişi tarafından şiddetin en ağır sonucuna maruz kalmıştır. Şiddetin boyutu ve etkilerinin ortaya konulması şiddetin kaynağının yok edilmesine katkı sağlayacaktır.     Anahtar Kelimeler: engelli çocuk; fiziksel istismar; ölüm</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2014</text>
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            <description>The topic of the resource</description>
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                <text>engelli çocuk, fiziksel istismar, Ölüm</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.17986/blm.2014193258</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Adli Tıp Bülteni</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="22105">
                <text>Adli Tıp Uzmanları Derneği</text>
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            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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            </elementTextContainer>
          </element>
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            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="22107">
                <text>EN, TR</text>
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            </elementTextContainer>
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                <text>Solutions of Ternary Problems of Conditional Probability with Applications to Mathematical Epidemiology and the COVID-19 Pandemic</text>
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                <text>Ali Muhammad Ali Rushdi, Hamzah Abdul Majid Serag</text>
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            <description>An account of the resource</description>
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                <text>A normalized version of the ubiquitous two-by-two contingency matrix is associated with a variety of marginal, conjunctive, and conditional probabilities that serve as appropriate indicators in diagnostic testing. If this matrix is enhanced by being interpreted as a probabilistic Universe of Discourse, it still suffers from two inter-related shortcomings, arising from lack of length/area proportionality and a potential misconception concerning a false assumption of independence between the two underlying events. This paper remedies these two shortcomings by modifying this matrix into a new Karnaugh-map-like diagram that resembles an eikosogram. Furthermore, the paper suggests the use of a pair of functionally complementary versions of this diagram to handle any ternary problem of conditional probability. The two diagrams split the unknowns and equations between themselves in a fashion that allows the use of a divide-and-conquer strategy to handle such a problem. The method of solution is demonstrated via four examples, in which the solution might be arithmetic or algebraic, and independently might be numerical or symbolic. In particular, we provide a symbolic arithmetic derivation of the well-known formulas that express the predictive values in terms of prevalence, sensitivity and specificity. Moreover, we prove a virtually unknown interdependence among the two predictive values, sensitivity, and specificity. In fact, we employ a method of symbolic algebraic derivation to express any one of these four indicators in terms of the other three. The contribution of this paper to the diagnostic testing aspects of mathematical epidemiology culminates in a timely application to the estimation of the true prevalence of the contemporary world-wide COVID-19 pandemic. It turns out that this estimation is hindered more by the lack of global testing world-wide rather than by the unavoidable imperfection of the available testing methods.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="42339">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="42340">
                <text>covid-19, Mathematical epidemiology, Conditional probability, divide-and-conquer, imperfect testing, ternary problem, length/area proportionality, probabilistic dependence</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="42341">
                <text>10.33889/IJMEMS.2020.5.5.062</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="42342">
                <text>International Journal of Mathematical, Engineering and Management Sciences</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="42343">
                <text>International Journal of Mathematical, Engineering and Management Sciences</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Mathematics, Technology</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
          </elementContainer>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>Training Manual for Prevention of Covid-19 Disease among Hospital Personnel</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="35897">
                <text>Ali Poormohammadi, Ghasem Azarian</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Dear EditorIn recent days, coronavirus disease (COVID-19) as a viral infection caused by the SARS-Cov-2 virus has become a pandemic disease and has created critical conditions worldwide [1]. According to previous studies on pathogenic viruses associated with acute respiratory distress syndrome, each virus has a specific virulence dose, which it is about 2×103-3×103 viral particles for the influenza virus. Given the emergence of the SARSCov-2 virus and no complete information on its virulence dose, it is clear that its very low virulence dose can cause its rapid spread. Regarding the effectiveness of the use of simple cloth filter masks, it can be stated that these masks provide relative safety depending on their type and structure [2]. In this regard, Blachere et al., reported that in multi-stage sampling of influenza viruses, 46% of the viruscontaining particles are trapped in the first filter layer of the sampler with a diameter of 4 microns, 49% of the viral particles are trapped in the second layer filter with a diameter 1 to 4 microns and only 1% of viruses are trapped in the last layer filter with a diameter of about 1 micron [2-4]. Coughing, sneezing, speaking, and breathing create a cloud of particles in the air with varying diameters ranging from a few millimeters to</text>
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            <name>Date</name>
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                <text>2020</text>
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          <element elementId="49">
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            <description>The topic of the resource</description>
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                <text>coronavirus, hospital personnel, Training Manual, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="35901">
                <text>DOI: 10.29252/jech.7.2.69</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="35902">
                <text>Journal of Education and Community Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="35903">
                <text>Hamadan University of Medical Sciences</text>
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            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="35904">
                <text>Public aspects of medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
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