463 10 20655 https://socictopen.socict.org/files/original/16212e5a7ccdcdc75eb0e6ac4ed8ae2a.pdf 17b2a9321dc844a290af28eaec9bbe5a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronaviruses in the Sea Creator An entity primarily responsible for making the resource Ian Hewson, Gideon J. Mordecai Description An account of the resource Interest in coronaviruses because of the 2019 novel coronavirus (SARS-CoV-2) pandemic has generated concern about their occurrence and persistence in aquatic habitats. Coronaviruses are not quantitatively significant constituents of marine virioplankton. Members of the Nidovirales (to which human coronaviruses belong) infect marine mammals, teleosts and possibly invertebrates, and human coronaviruses may persist in marine plankton receiving wastewater effluent. However, virions likely experience significant particle and infectivity decay rates in surface seawater, similar to other enveloped RNA viruses. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, Virome, disease, virioplankton, Nidovirales Identifier An unambiguous reference to the resource within a given context 10.3389/fmicb.2020.01795 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://socictopen.socict.org/files/original/51b0098ae5942a5a682f6ce3427e72cc.pdf 5e956bd86d6749c315548d1f6a71cff1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics. Creator An entity primarily responsible for making the resource Everett Clinton Smith, Hervé Blanc, Matthew C Surdel, Marco Vignuzzi, Mark R. Denison Description An account of the resource No therapeutics or vaccines currently exist for human coronaviruses (HCoVs). The Severe Acute Respiratory Syndrome-associated coronavirus (SARS-CoV) epidemic in 2002-2003, and the recent emergence of Middle East Respiratory Syndrome coronavirus (MERS-CoV) in April 2012, emphasize the high probability of future zoonotic HCoV emergence causing severe and lethal human disease. Additionally, the resistance of SARS-CoV to ribavirin (RBV) demonstrates the need to define new targets for inhibition of CoV replication. CoVs express a 3'-to-5' exoribonuclease in nonstructural protein 14 (nsp14-ExoN) that is required for high-fidelity replication and is conserved across the CoV family. All genetic and biochemical data support the hypothesis that nsp14-ExoN has an RNA proofreading function. Thus, we hypothesized that ExoN is responsible for CoV resistance to RNA mutagens. We demonstrate that while wild-type (ExoN+) CoVs were resistant to RBV and 5-fluorouracil (5-FU), CoVs lacking ExoN activity (ExoN-) were up to 300-fold more sensitive. While the primary antiviral activity of RBV against CoVs was not mutagenesis, ExoN- CoVs treated with 5-FU demonstrated both enhanced sensitivity during multi-cycle replication, as well as decreased specific infectivity, consistent with 5-FU functioning as a mutagen. Comparison of full-genome next-generation sequencing of 5-FU treated SARS-CoV populations revealed a 16-fold increase in the number of mutations within the ExoN- population as compared to ExoN+. Ninety percent of these mutations represented A:G and U:C transitions, consistent with 5-FU incorporation during RNA synthesis. Together our results constitute direct evidence that CoV ExoN activity provides a critical proofreading function during virus replication. Furthermore, these studies identify ExoN as the first viral protein distinct from the RdRp that determines the sensitivity of RNA viruses to mutagens. Finally, our results show the importance of ExoN as a target for inhibition, and suggest that small-molecule inhibitors of ExoN activity could be potential pan-CoV therapeutics in combination with RBV or RNA mutagens. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.ppat.1003565 Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy Language A language of the resource EN https://socictopen.socict.org/files/original/c208ca5e800d151a1f69a1e05bf68c6b.pdf ed8c45ac730b2bf73ecaf0dd781b0724 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronaviruses: Molecular and Cellular Biology Creator An entity primarily responsible for making the resource Julian L. Leibowitz Date A point or period of time associated with an event in the lifecycle of the resource 2008 Subject The topic of the resource coronaviruses, molecular biology, book review Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1404.080016 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://socictopen.socict.org/files/original/2cfcf3860158c6be92cd074d1f3997da.pdf 2236bb2be203c284373b70903bd9e46e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource CoronaVR: A Computational Resource and Analysis of Epitopes and Therapeutics for Severe Acute Respiratory Syndrome Coronavirus-2 Creator An entity primarily responsible for making the resource Amit Kumar Gupta, Md. Shoaib Khan, Shubham Choudhury, Adhip Mukhopadhyay, Adhip Mukhopadhyay, Sakshi, Sakshi, Amber Rastogi, Amber Rastogi, Anamika Thakur, Anamika Thakur, Pallawi Kumari, Manmeet Kaur, Shalu, Chanchal Saini, Vandna Sapehia, Barkha, Pradeep Kumar Patel, Kailash T. Bhamare, Manoj Kumar, Manoj Kumar Description An account of the resource In December 2019, the Chinese city of Wuhan was the center of origin of a pneumonia-like disease outbreak with an unknown causative pathogen. The CDC, China, managed to track the source of infection to a novel coronavirus (2019-nCoV; SARS-CoV-2) that shares approximately 79.6% of its genome with SARS-CoV. The World Health Organization (WHO) initially declared COVID-19 as a Public Health Emergency of International Concern (PHEIC) and later characterized it as a global pandemic on March 11, 2020. Due to the novel nature of this virus, there is an urgent need for vaccines and therapeutics to control the spread of SARS-CoV-2 and its associated disease, COVID-19. Global efforts are underway to circumvent its further spread and treat COVID-19 patients through experimental vaccine formulations and therapeutic interventions, respectively. In the absence of any effective therapeutics, we have devised h bioinformatics-based approaches to accelerate global efforts in the fight against SARS-CoV-2 and to assist researchers in the initial phase of vaccine and therapeutics development. In this study, we have performed comprehensive meta-analyses and developed an integrative resource, “CoronaVR” (http://bioinfo.imtech.res.in/manojk/coronavr/). Predominantly, we identified potential epitope-based vaccine candidates, siRNA-based therapeutic regimens, and diagnostic primers. The resource is categorized into the main sections “Genomes,” “Epitopes,” “Therapeutics,” and Primers.” The genome section harbors different components, viz, genomes, a genome browser, phylogenetic analysis, codon usage, glycosylation sites, and structural analysis. Under the umbrella of epitopes, sub-divisions, namely cross-protective epitopes, B-cell (linear/discontinuous), T-cell (CD4+/CD8+), CTL, and MHC binders, are presented. The therapeutics section has different sub-sections like siRNA, miRNAs, and sgRNAs. Further, experimentally confirmed and designed diagnostic primers are earmarked in the primers section. Our study provided a set of shortlisted B-cell and T-cell (CD4+ and CD8+) epitopes that can be experimentally tested for their incorporation in vaccine formulations. The list of selected primers can be used in testing kits to identify SARS-CoV-2, while the recommended siRNAs, sgRNAs, and miRNAs can be used in therapeutic regimens. We foresee that this resource will help in advancing the research against coronaviruses. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource 2019ncov, covid-19, SARS-CoV-2, therapeutics, epitopes, Primers Identifier An unambiguous reference to the resource within a given context 10.3389/fmicb.2020.01858 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://socictopen.socict.org/files/original/83afcc7aa3bade24ca801dbad674296a.pdf 2538e56c65497018b1aa8c6f88d8c651 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Corporação e economia local: uma análise usando Contas Sociais Alfa (CS?) do programa de investimentos da CVRD no Sudeste Paraense (2004 a 2010) Creator An entity primarily responsible for making the resource Francisco de Assis Costa Description An account of the resource O Sudeste Paraense tem sido uma região de extraordinária dinâmica. Lá se alocaram os grandes projetos pecuários financiados pela SUDAM desde meados dos anos sessenta, os quais confrontaram a velha economia dos castanhais e frentes de expansão da agricultura familiar, espontâneas e induzidas, ao lado de grandes projetos minerais e de surtos garimpeiros. Como partes do processo ocorreram transformações estruturais importantes que reforçaram o papel dos centros urbanos e suas bases rurais locais na logística de novos setores econômicos condicionados pela formação da economia mineral resultante da presença da Companhia Vale do Rio Doce (CVRD), que desde 1985 lá opera seu sistema norte de metais ferrosos com base em Carajás. O artigo apresenta resultados de uma análise de insumo-produto com metodologia ascendente que explicita a diversidade estrutural dos setores de base primária – os impactos econômicos da programação de investimento da CVRD de 2004 até 2010. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Subject The topic of the resource Amazônia, economia mineral, economía local, sudeste paraense Source A related resource from which the described resource is derived Nova Economia Publisher An entity responsible for making the resource available Universidade Federal de Minas Gerais Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Economic theory. Demography, Economic history and conditions Relation A related resource <a href="http://revistas.face.ufmg.br/index.php/novaeconomia/article/view/1033" target="_blank" rel="noreferrer noopener">http://revistas.face.ufmg.br/index.php/novaeconomia/article/view/1033</a> https://socictopen.socict.org/files/original/0fb1e9a5b8909103e566e83e6f6004d6.pdf 537812f3e09d23ae6aa0f5f87f538e5e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Corporate social responsibility plan for the real estate sector Creator An entity primarily responsible for making the resource Cecilia Ivonne Narváez-Zurita, Juan Carlos Erazo-Álvarez, Verónica Paulina Moreno, Giovanny Miguel Yauri-Santos Description An account of the resource Corporate social responsibility as a voluntary agreement between companies and society to help achieve sustainability objectives, including environmental ones, is an argument for achieving business advantages in the market. So the objective of the research is to design a corporate social responsibility plan for real estate companies in the city of Cuenca. The type of research was non-experimental, had a qualitative and quantitative orientation and the scope of the study was descriptive-explanatory. The methods used were the historical-logical, analytical-synthetic, deductive-inductive and the systemic method. The results demonstrated how basic it is to have social responsibility in companies and not only that, also to design a plan and socialize people, the same ones who widely understand the concept of sustainability and support and idealize this in large companies, especially in real estate agents as intermediaries to satisfy a primary need. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource EMPRESA PRIVADA, Responsabilidad Social, ecología, marketing Identifier An unambiguous reference to the resource within a given context 10.35381/r.k.v5i10.845 Source A related resource from which the described resource is derived Revista Arbitrada Interdisciplinaria Koinonía Publisher An entity responsible for making the resource available Fundación Koinonia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General), General Works Relation A related resource <a href="https://fundacionkoinonia.com.ve/ojs/index.php/revistakoinonia/article/view/845" target="_blank" rel="noreferrer noopener">https://fundacionkoinonia.com.ve/ojs/index.php/revistakoinonia/article/view/845</a> https://socictopen.socict.org/files/original/79b134815a22bff3e54604e777ab34ed.pdf 838d64ce27efad73b59611ed48305848 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Corporate social responsibility practices of business firms in Dubai during the COVID-19 pandemic Creator An entity primarily responsible for making the resource Abubaker Mousa Eltoum, Aminurraasyid Yatiban, Rusdi Omar, Rabiul Islam Description An account of the resource During the first quarter of 2020, COVID-19 spread worldwide, claiming lives of thousands of people every day. This marked the beginning of all emergency and business continuity plans around the world. This study attempts to study people’s awareness of CSR practices among business firms in Dubai and investigate people’s evaluation of these CSR practices during the COVID-19 pandemic. The study employs a quantitative research method and mainly uses questionnaires for data collection. 199 respondents are selected from different business firms in Dubai. Expert interviews are also conducted for triangulation purposes. It involves the Dubai community with various backgrounds and status. This study shows that a large scheme of the Dubai community has a decent level of expertise in sustainability and corporate social responsibility. It also shows that firms that have implemented CSR before the crisis will mostly be better suited to play a supportive role for government and society during the crisis.AcknowledgmentResearch grant provided by the Fundamental Research Grant Scheme [FRGS/1/2017/SS01/UUM/02/23] under Ministry of Higher Education, Malaysia, and University Utara Malaysia (SO Code: 13806) is gratefully acknowledged. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource sustainability, community, crisis, social capital, Corporate Social Responsibility Identifier An unambiguous reference to the resource within a given context 10.21511/ppm.19(1).2021.20 Source A related resource from which the described resource is derived Problems and Perspectives in Management Publisher An entity responsible for making the resource available LLC CPC "Business Perspectives"" Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Business https://socictopen.socict.org/files/original/cfc26e551989c0b349d95b4acd3fb69c.pdf ca0ea63127edb54850a648580773fe71 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correction to: A randomized, open-label, adaptive, proof-of-concept clinical trial of modulation of host thromboinflammatory response in patients with COVID-19: the DAWn-Antico study Creator An entity primarily responsible for making the resource T. Vanassche, M. M. Engelen, Q. Van Thillo, J. Wauters, J. Gunst, C. Wouters, C. Vandenbriele, S. Rex, L. Liesenborghs, A. Wilmer, P. Meersseman, G. Van den Berghe, D. Dauwe, G. Verbeke, M. Thomeer, T. Fivez, D. Mesotten, D. Ruttens, L. Heytens, I. Dapper, S. Tuyls, B. De Tavernier, P. Verhamme, DAWn consortium members Description An account of the resource An amendment to this paper has been published and can be accessed via the original article. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1186/s13063-020-04991-y Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://socictopen.socict.org/files/original/210c3b53b10addfaef03b6a7095ab44f.pdf 75cd4e209bde9cbfe2c3aa1cca6d16f9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correction to: BCG revaccination of health workers in Brazil to improve innate immune responses against COVID-19: A structured summary of a study protocol for a randomised controlled trial. Creator An entity primarily responsible for making the resource Ana Paula Junqueira-Kipnis, Laura Raniere Borges Dos Anjos, Lília Cristina de Souza Barbosa, Adeliane Castro da Costa, Kellen Christina Malheiros Borges, Amanda da Rocha Oliveira Cardoso, Kaio Mota Ribeiro, Sarah Brena Aparecida Rosa, Carine de Castro Souza, Rogério Coutinho das Neves, Guylherme Saraiva, Sueli Meira da Silva, Erika Aparecida Silveira, Marcelo Fouad Rabahi, Marcus Barreto Conte, André Kipnis Description An account of the resource An amendment to this paper has been published and can be accessed via the original article. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1186/s13063-020-04913-y Source A related resource from which the described resource is derived Trials https://socictopen.socict.org/files/original/e58610c82745218f8d0302c135da1513.pdf 28d3ce8703ae25f5364cda498ce122fa Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correction to: CT and clinical assessment in asymptomatic and pre-symptomatic patients with early SARS-CoV-2 in outbreak settings. Creator An entity primarily responsible for making the resource Nicole Varble, Maxime Blain, Michael Kassin, Sheng Xu, Evrim B Turkbey, Amel Amalou, Dilara Long, Stephanie Harmon, Thomas Sanford, Dong Yang, Ziyue Xu, Daguang Xu, Mona Flores, Peng An, Gianpaolo Carrafiello, Hirofumi Obinata, Hitoshi Mori, Kaku Tamura, Ashkan A Malayeri, Steven M Holland, Tara Palmore, Kaiyuan Sun, Baris Turkbey, Bradford J Wood Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1007/s00330-020-07552-8 Source A related resource from which the described resource is derived European radiology