https://socictopen.socict.org/files/original/4cdd9ee7049042520181d14860ea932d.pdf 0cd3c2c1ca33e9b4b799cee7304f4b8c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Is the COVID-19 Pandemic a Good Time to Include <i>Aspergillus</i> Molecular Detection to Categorize Aspergillosis in ICU Patients? A Monocentric Experience Creator An entity primarily responsible for making the resource Jean-Pierre Gangneux, Florian Reizine, Hélène Guegan, Kieran Pinceaux, Pierre Le Balch, Emilie Prat, Romain Pelletier, Sorya Belaz, Mathieu Le Souhaitier, Yves Le Tulzo, Philippe Seguin, Mathieu Lederlin, Jean-Marc Tadié, Florence Robert-Gangneux Description An account of the resource (1) Background: The diagnosis of invasive aspergillosis (IA) in an intensive care unit (ICU)remains a challenge and the COVID-19 epidemic makes it even harder. Here, we evaluatedAspergillus PCR input to help classifying IA in SARS-CoV-2-infected patients. (2) Methods: 45COVID-19 patients were prospectively monitored twice weekly for Aspergillus markers and anti-Aspergillus serology. We evaluated the concordance between (Ι) Aspergillus PCR and culture inrespiratory samples, and (ΙΙ) blood PCR and serum galactomannan. Patients were classified asputative/proven/colonized using AspICU algorithm and two other methods. (3) Results: Theconcordance of techniques applied on respiratory and blood samples was moderate (kappa = 0.58and kappa = 0.63, respectively), with a higher sensitivity of PCR. According to AspICU, 9/45 patientswere classified as putative IA. When incorporating PCR results, 15 were putative IA because theymet all criteria, probably with a lack of specificity in the context of COVID-19. Using a modifiedAspICU algorithm, eight patients were classified as colonized and seven as putative IA. (4)Conclusion: An appreciation of the fungal burden using PCR and Aspergillus serology was addedto propose a modified AspICU algorithm. This proof of concept seemed relevant, as it was inagreement with the outcome of patients, but will need validation in larger cohorts. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource ICU, covid-19, SARS-CoV-2, Invasive aspergillosis, Probable, putative Identifier An unambiguous reference to the resource within a given context 10.3390/jof6030105 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General)