https://socictopen.socict.org/files/original/58f1f2c2529fbce242929f20048290b9.pdf 757f2b043d518cdcaca2dfeee6b81af6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses Creator An entity primarily responsible for making the resource Javier A. Jaimes, Jean K. Millet, Alison E Stout, Nicole M André, Gary R. Whittaker Description An account of the resource Feline coronavirus (FCoV) is a complex viral agent that causes a variety of clinical manifestations in cats, commonly known as feline infectious peritonitis (FIP). It is recognized that FCoV can occur in two different serotypes. However, differences in the S protein are much more than serological or antigenic variants, resulting in the effective presence of two distinct viruses. Here, we review the distinct differences in the S proteins of these viruses, which are likely to translate into distinct biological outcomes. We introduce a new concept related to the non-taxonomical classification and differentiation among FCoVs by analyzing and comparing the genetic, structural, and functional characteristics of FCoV and the FCoV S protein among the two serotypes and FCoV biotypes. Based on our analysis, we suggest that our understanding of FIP needs to consider whether the presence of these two distinct viruses has implications in clinical settings. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Feline coronavirus, feline infectious peritonitis, spike protein, Serotype, Genetic characterization Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12010083 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN