https://socictopen.socict.org/files/original/cc02997a96d08025c7523592b04ea23f.pdf 10d65fe7b082c7b2bb7c940e4e21aa34 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Novel Coronavirus Infection (COVID-19) in Humans: A Scoping Review and Meta-Analysis Creator An entity primarily responsible for making the resource Israel Júnior Borges do Nascimento, Nensi Cacic, Hebatullah Mohamed Abdulazeem, Thilo Caspar von Groote, Umesh Jayarajah, Ishanka Weerasekara, Meisam Abdar-Esfahani, Vinicius Tassoni Civile, Ana Marušić, Ana Jerončić, Nelson Carvas Junior, Tina Poklepović Peričić, Irena Zakarija-Grković, Silvana Mangeon Meirelles Guimarães, Nicola Luigi Bragazzi, Maria Björklund, Ahmad Sofi-Mahmudi, Mohammad Altujjar, Maoyi Tian, Diana Maria Cespedes Arcani, Dónal P. O’Mathúna, Milena Soriano Marcolino Description An account of the resource A growing body of literature on the 2019 novel coronavirus (SARS-CoV-2) is becoming available, but a synthesis of available data has not been conducted. We performed a scoping review of currently available clinical, epidemiological, laboratory, and chest imaging data related to the SARS-CoV-2 infection. We searched MEDLINE, Cochrane CENTRAL, EMBASE, Scopus and LILACS from 01 January 2019 to 24 February 2020. Study selection, data extraction and risk of bias assessment were performed by two independent reviewers. Qualitative synthesis and meta-analysis were conducted using the clinical and laboratory data, and random-effects models were applied to estimate pooled results. A total of 61 studies were included (59,254 patients). The most common disease-related symptoms were fever (82%, 95% confidence interval (CI) 56%–99%; n = 4410), cough (61%, 95% CI 39%–81%; n = 3985), muscle aches and/or fatigue (36%, 95% CI 18%–55%; n = 3778), dyspnea (26%, 95% CI 12%–41%; n = 3700), headache in 12% (95% CI 4%–23%, n = 3598 patients), sore throat in 10% (95% CI 5%–17%, n = 1387) and gastrointestinal symptoms in 9% (95% CI 3%–17%, n = 1744). Laboratory findings were described in a lower number of patients and revealed lymphopenia (0.93 × 109/L, 95% CI 0.83–1.03 × 109/L, n = 464) and abnormal C-reactive protein (33.72 mg/dL, 95% CI 21.54–45.91 mg/dL; n = 1637). Radiological findings varied, but mostly described ground-glass opacities and consolidation. Data on treatment options were limited. All-cause mortality was 0.3% (95% CI 0.0%–1.0%; n = 53,631). Epidemiological studies showed that mortality was higher in males and elderly patients. The majority of reported clinical symptoms and laboratory findings related to SARS-CoV-2 infection are non-specific. Clinical suspicion, accompanied by a relevant epidemiological history, should be followed by early imaging and virological assay. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource novel coronavirus, SARS-CoV-2, COVID-19, scoping review, Meta-analysis Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/jcm9040941 Source A related resource from which the described resource is derived Journal of Clinical Medicine Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN