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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Dominio científico: Coronavirus</text>
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        <element elementId="50">
          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Prognostic value of NT-proBNP in patients with severe COVID-19</text>
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        <element elementId="39">
          <name>Creator</name>
          <description>An entity primarily responsible for making the resource</description>
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              <text>Lei Gao, Dan Jiang, Xuesong Wen, Xiao-cheng Cheng, Min SUN, Bin He, Lin-na You, Peng Lei, Xiao Wei Tan, Shu Qin, Guoqiang Cai, Dongying Zhang</text>
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        <element elementId="41">
          <name>Description</name>
          <description>An account of the resource</description>
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              <text>Abstract Background The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a public health emergency of international concern. The cardiac injury is a common condition among the hospitalized patients with COVID-19. However, whether N terminal pro B type natriuretic peptide (NT-proBNP) predicted outcome of severe COVID-19 patients was unknown. Methods The study initially enrolled 102 patients with severe COVID-19 from a continuous sample. After screening out the ineligible cases, 54 patients were analyzed in this study. The primary outcome was in-hospital death defined as the case fatality rate. Research information and following-up data were obtained from their medical records. Results The best cut-off value of NT-proBNP for predicting in-hospital death was 88.64 pg/mL with the sensitivity for 100% and the specificity for 66.67%. Patients with high NT-proBNP values (&gt; 88.64 pg/mL) had a significantly increased risk of death during the days of following-up compared with those with low values (≤88.64 pg/mL). After adjustment for potential risk factors, NT-proBNP was independently correlated with in-hospital death. Conclusion NT-proBNP might be an independent risk factor for in-hospital death in patients with severe COVID-19. Trial registration ClinicalTrials, NCT04292964. Registered 03 March 2020,</text>
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          <name>Date</name>
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              <text>2020</text>
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          <name>Subject</name>
          <description>The topic of the resource</description>
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            <elementText elementTextId="16412">
              <text>NT-proBNT, COVID-19, SARS-CoV-2, outcome</text>
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          <name>Identifier</name>
          <description>An unambiguous reference to the resource within a given context</description>
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              <text>DOI: 10.1186/s12931-020-01352-w</text>
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        <element elementId="48">
          <name>Source</name>
          <description>A related resource from which the described resource is derived</description>
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            <elementText elementTextId="16414">
              <text>Respiratory Research</text>
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          </elementTextContainer>
        </element>
        <element elementId="45">
          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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              <text>BMC</text>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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            <elementText elementTextId="16416">
              <text>Diseases of the respiratory system</text>
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          <name>Language</name>
          <description>A language of the resource</description>
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              <text>EN</text>
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