https://socictopen.socict.org/files/original/c3d41a2b3d6657d2c0962d3654522c5b.pdf 46c207e37c0fa7abc74ea152dad7073d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Baculovirus: Hospederos y especificidad Creator An entity primarily responsible for making the resource Juliana Gómez Valderrama, Laura Villamizar Description An account of the resource Título corto: Baculovirus Título en ingles: Baculovirus: Hosts and specificity Resumen: Los baculovirus son virus patógenos de insectos ampliamente empleados a nivel mundial como bioinsecticidas para el control de diferentes plagas de importancia agrícola y más recientemente como vectores de expresión de proteínas y vectores para terapia génica. Una de sus características principales es su alta especificidad de hospedero que incluye un rango muy estrecho de especies de insectos, que a menudo pertenecen a la misma familia. Sin embargo, es necesario entender los mecanismos involucrados en la definición del rango de hospederos de los baculovirus con el fin de evaluar la seguridad e inocuidad de su uso y determinar la posibilidad de mejorar sus propiedades para aplicaciones biotecnológicas mediante la construcción de baculovirus recombinantes con diferentes rangos de hospederos. En el presente artículo se revisarán los principales mecanismos comprendidos en la definición del rango de hospederos de los baculovirus, dentro de los que se destacan la especificidad para entrar en las células, la posibilidad de replicación del genoma viral, el control de los procesos bioquímicos y moleculares del insecto y las interacciones virus-hospedero que regulan la multiplicación del agente infeccioso, así como las perspectivas de la aplicación de este conocimiento. Palabras clave: infección viral, rango de hospederos, evolución, resistencia. Abstract: Baculoviruses are insect pathogenic viruses widely used as bioinsecticides for controlling of several agricultural important pests and more recently as protein expression vectors and gene therapy vectors. One of its main characteristics is its high host-specificity including a very narrow range of insect species, which often belong to the same family. However, to understand the mechanisms involved in the definition of baculoviruses host range is necessary in order to assess the security and safety of its use and to determine the possibility of improving their properties for biotechnological applications through the construction of recombinant baculovirus with different host ranges. In the present article the main mechanisms involved in baculoviruses host range as specificity for entering into the host cells, the possibility of viral genome replication, the control of biochemical and molecular insect processes and the interactions virus-host regulating the multiplication of the infectious agent, and the prospects of applying this knowledge will be reviewed. Key words: viral infection, host range, evolution, resistance. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Subject The topic of the resource Evolución, Host range, evolution, infección viral, rango de hospederos, resistance, resistencia, viral infection Identifier An unambiguous reference to the resource within a given context 10.15446/rev.colomb.biote.v15n2.41273 Source A related resource from which the described resource is derived Revista Colombiana de Biotecnología Publisher An entity responsible for making the resource available Universidad Nacional de Colombia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biotechnology Relation A related resource <a href="https://revistas.unal.edu.co/index.php/biotecnologia/article/view/41273" target="_blank" rel="noreferrer noopener">https://revistas.unal.edu.co/index.php/biotecnologia/article/view/41273</a>