https://socictopen.socict.org/files/original/31bf2bfa46b4cc3d7457ee1f35f27638.pdf 0fcea00e407023c9f35d19794a5d4255 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Serologic and Molecular Biologic Methods for SARS-associated Coronavirus Infection, Taiwan Creator An entity primarily responsible for making the resource Ho-Sheng Wu, Shu-Chun Chiu, Tsan-Chang Tseng, Szu-Fong Lin, Jih-Hui Lin, Yu-Fen Hsu, Mei-Ching Wang, Tsuey-Li Lin, Wen-Zieh Yang, Tian-Lin Ferng, Kai-Hung Huang, Li-Ching Hsu, Li-Li Lee, Jyh-Yuan Yang, Hour-Young Chen, Shun-Pi Su, Shih-Yan Yang, Ting Hsiang Lin, Ih-Jen Su Description An account of the resource Severe acute respiratory syndrome (SARS) has raised a global alert since March 2003. After its causative agent, SARS-associated coronavirus (SARS-CoV), was confirmed, laboratory methods, including virus isolation, reverse transcriptase–polymerase chain reaction (RT-PCR), and serologic methods, have been quickly developed. In this study, we evaluated four serologic tests ( neutralization test, enzyme-linked immunosorbent assay [ELISA], immunofluorescent assay [IFA], and immunochromatographic test [ICT]) for detecting antibodies to SARS-CoV in sera of 537 probable SARS case-patients with correlation to the RT-PCR . With the neutralization test as a reference method, the sensitivity, specificity, positive predictive value, and negative predictive value were 98.2%, 98.7%, 98.7%, and 98.4% for ELISA; 99.1%, 87.8%, 88.1% and 99.1% for IFA; 33.6%, 98.2%, 95.7%, and 56.1% for ICT, respectively. We also compared the recombinant-based western blot with the whole virus–based IFA and ELISA; the data showed a high correlation between these methods, with an overall agreement of >90%. Our results provide a systematic analysis of serologic and molecular methods for evaluating SARS-CoV infection. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource SARS-CoV, Serodiagnostic methods, Neutralization test, IFA, ELISA, Immunochromatographic test Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1002.030731 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN