Nucleocapsid Protein as Early Diagnostic Marker for SARS

Nucleocapsid Protein as Early Diagnostic Marker for SARS

Xiao-Yan Che, Wei Hao, Yadi Wang, Biao Di, Kai Yin, Yin-Chao Xu, Changsen Feng, Zhuo-Yue Wan, Vincent C.C. Cheng, Patrick C. Y. Woo

Serum samples from 317 patients with patients with severe acute respiratory syndrome (SARS) were tested for the nucleocapsid (N) protein of SARS-associated coronavirus, with sensitivities of 94% and 78% for the first 5 days and 6–10 days after onset, respectively. The specificity was 99.9%. N protein can be used as an early diagnostic maker for SARS.

2004

SARS-CoV, Nucleocapsid protein, Monoclonal antibody, Enzyme-Linked Immunosorbent Assay, Early diagnosis, severe acute respiratory syndrome, dispatch, China

DOI: 10.3201/eid1011.040516

Emerging Infectious Diseases

Centers for Disease Control and Prevention

Infectious and parasitic diseases, Medicine

EN