Domestic Pig Unlikely Reservoir for MERS-CoV
subject: Middle East respiratory syndrome coronavirus, MERS-CoV, animal models, domestic pig, dipeptidyl peptidase-4, DPP4
description: We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikely to constitute a reservoir in nature.
creator: Emmie de Wit, Friederike Feldmann, Eva Horne, Cynthia Martellaro, Elaine Haddock, Trenton Bushmaker, Kyle Rosenke, Atsushi Okumura, Rebecca Rosenke, Greg Saturday, Dana Scott, Heinz Feldmann
source: Emerging Infectious Diseases
publisher: Centers for Disease Control and Prevention
date: 2017
language: EN
identifier: DOI: 10.3201/eid2306.170096
coverage: Infectious and parasitic diseases, Medicine