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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Severe Acute Respiratory Syndrome: Clinical Outcome and Prognostic Correlates</text>
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          <name>Creator</name>
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              <text>Ping Tim Tsui, Man Leung Kwok, Hon Yuen, Sik To Lai</text>
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          <name>Description</name>
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              <text>Severe acute respiratory syndrome (SARS) poses a major threat to the health of people worldwide. We performed a retrospective case series analysis to assess clinical outcome and identify pretreatment prognostic correlates of SARS, managed under a standardized treatment protocol. We studied 127 male and 196 female patients with a mean age of 41±14 (range 18–83). All patients, except two, received ribavirin and steroid combination therapy. In 115 (36%) patients, the course of disease was limited. Pneumonitis progressed rapidly in the remaining patients. Sixty-seven (21%) patients required intensive care, and 42 (13%) required ventilator support. Advanced age, high admission neutrophil count, and high initial lactate dehydrogenase level were independent correlates of an adverse clinical outcome. SARS-associated coronavirus caused severe illnesses in most patients, despite early treatment with ribavirin and steroid. This study has identified three independent pretreatment prognostic correlates.</text>
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          <name>Date</name>
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              <text>2003</text>
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              <text>severe acute respiratory syndrome, clinical outcome, ribavirin, steroid, Hong Kong, China</text>
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          <name>Identifier</name>
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              <text>DOI: 10.3201/eid0909.030362</text>
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          <name>Source</name>
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              <text>Emerging Infectious Diseases</text>
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          <name>Publisher</name>
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              <text>Centers for Disease Control and Prevention</text>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <text>Infectious and parasitic diseases, Medicine</text>
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          <name>Language</name>
          <description>A language of the resource</description>
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              <text>EN</text>
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