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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Dominio científico: Coronavirus</text>
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        <element elementId="50">
          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Genome-wide analysis of codon usage bias in Bovine Coronavirus</text>
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          <name>Creator</name>
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            <elementText elementTextId="22315">
              <text>Matías Castells, Matias Victoria, Rodney Colina, Hector Musto, Juan Cristina</text>
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          <name>Description</name>
          <description>An account of the resource</description>
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              <text>Abstract Background Bovine coronavirus (BCoV) belong to the genus Betacoronavirus of the family Coronaviridae. BCoV are widespread around the world and cause enteric or respiratory infections among cattle, leading to important economic losses to the beef and dairy industry worldwide. To study the relation of codon usage among viruses and their hosts is essential to understand host-pathogen interaction, evasion from host’s immune system and evolution. Methods We performed a comprehensive analysis of codon usage and composition of BCoV. Results The global codon usage among BCoV strains is similar. Significant differences of codon preferences in BCoV genes in relation to codon usage of Bos taurus host genes were found. Most of the highly frequent codons are U-ending. G + C compositional constraint and dinucleotide composition also plays a role in the overall pattern of BCoV codon usage. Conclusions The results of these studies revealed that mutational bias is a leading force shaping codon usage in this virus. Additionally, relative dinucleotide frequencies, geographical distribution, and evolutionary processes also influenced the codon usage pattern.</text>
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              <text>2017</text>
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          <name>Subject</name>
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              <text>bovine, coronavirus, codon usage, evolution</text>
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          <name>Identifier</name>
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              <text>DOI: 10.1186/s12985-017-0780-y</text>
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        <element elementId="48">
          <name>Source</name>
          <description>A related resource from which the described resource is derived</description>
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            <elementText elementTextId="22320">
              <text>Virology Journal</text>
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        <element elementId="45">
          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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            <elementText elementTextId="22321">
              <text>BMC</text>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
          <elementTextContainer>
            <elementText elementTextId="22322">
              <text>Infectious and parasitic diseases</text>
            </elementText>
          </elementTextContainer>
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          <name>Language</name>
          <description>A language of the resource</description>
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            <elementText elementTextId="22323">
              <text>EN</text>
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