The Paradox of Feline Coronavirus Pathogenesis: A Review

The Paradox of Feline Coronavirus Pathogenesis: A Review

Abelardo Silva Júnior, Mauricio Resende, Luciana Wanderley Myrrha, Fernanda Miquelitto Figueira Silva, Ethel Fernandes de Oliveira Peternelli, Márcia Rogéria de Almeida

Feline coronavirus (FCoV) is an enveloped single-stranded RNA virus, of the family Coronaviridae and the order Nidovirales. FCoV is an important pathogen of wild and domestic cats and can cause a mild or apparently symptomless enteric infection, especially in kittens. FCoV is also associated with a lethal, systemic disease known as feline infectious peritonitis (FIP). Although the precise cause of FIP pathogenesis remains unclear, some hypotheses have been suggested. In this review we present results from different FCoV studies and attempt to elucidate existing theories on the pathogenesis of FCoV infection.

2011

DOI: 10.1155/2011/109849

Advances in Virology

Hindawi Limited

Microbiology