The Emergence of Novel-Coronavirus and its Replication Cycle - An Overview
replication, infection, emergence, Respiratory disease, 2019ncov, COVID-19
Recently, a new viral-based infection has emerged as a respiratory disease caused by a novel (new)coronavirus that was first detected in Wuhan City, China. With any or many reasons, this newly emergednovel-Coronavirus (2019-nCoV) has now been recognized in more than 70 locations around the globe.The disease caused by 2019-nCoV has been named as “coronavirus disease 2019 – COVID-19”. Due tothe rising number of confirmed 2019-nCoV infected cases and widespread detection, the World HealthOrganization (WHO) has announced 2019-nCoV as a threatening health concern, and urgent robustactions are of supreme interest to tackle this global health emergency. Owing to this new emergence,we know relatively little about 2019-nCoV, which is a highly pathogenic human pathogen. To completelyovercome this life-threatening 2019-nCoV pathogen, further in-depth studies are needed to gain insightand complete understanding about its fast mode spread, replication, and pathogenesis. Since the firstappearance and detection of 2019-nCoV and COVID-19, respectively, the current literature lacks theglobal perspective and replication cycle of 2019-nCoV. Thus, herein, an effort has been made to cover thisliterature gap. A proper understanding of the 2019-nCoV replication will further insight and strengthenthe infection control measures, transmission prevention, and vaccine development, effectively.
Muhammad Bilal, Roberto Parra-Saldívar, Hafiz M. N. Iqbal, Kenya D. Romero-Castillo
Journal of Pure and Applied Microbiology