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            <name>Title</name>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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              <text>Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing.</text>
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              <text>Xiaoyan Yu, Rou-Jian Lu, Zhong Wang, Na Zhu, Wen Wang, Druce Julian, Birch Chris, Jianxin Lu, Wen-Jie Tan</text>
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              <text>BACKGROUND: Acute respiratory tract infections (ARTIs) represent a serious global health burden. To date, few reports have addressed the prevalence of respiratory viruses (RVs) in adults with ARTIs attending an emergency department (ED). Therefore, the potential impact of respiratory virus infections on such patients remains unknown. METHODOLOGY/PRINCIPAL FINDINGS: To determine the epidemiological and clinical profiles of common and recently discovered respiratory viruses in adults with ARTIs attending an ED in Beijing, a 1-year consecutive study was conducted from May, 2010, to April, 2011. Nose and throat swab samples from 416 ARTI patients were checked for 13 respiratory viruses using multiple reverse transcription polymerase chain reaction(RT-PCR) assays for common respiratory viruses, including influenza viruses (Flu) A, B, and adenoviruses (ADVs), picornaviruses (PICs), respiratory syncytial virus (RSV), parainfluenza viruses (PIVs) 1-3, combined with real-time RT-PCR for human metapneumovirus (HMPV) and human coronaviruses (HCoVs, -OC43, -229E, -NL63, and -HKU1). Viral pathogens were detected in 52.88% (220/416) of patient samples, and 7.21% (30/416) of patients tested positive for more than one virus. PICs (17.79%) were the dominant agents detected, followed by FluA (16.11%), HCoVs (11.78%), and ADV (11.30%). HMPV, PIVs, and FluB were also detected (</text>
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              <text>2012</text>
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              <text>DOI: 10.1371/journal.pone.0032174</text>
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              <text>PLoS ONE</text>
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          <name>Publisher</name>
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              <text>Public Library of Science (PLoS)</text>
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          <name>Coverage</name>
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              <text>Science, Medicine</text>
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              <text>EN</text>
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