https://socictopen.socict.org/files/original/ad80a523c6595265ac9e62dfb0c2258d.pdf 29af869f2d62bd2872e4b0bbd14626c9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Severe COVID-19, Another Piece in the Puzzle of the Hyperferritinemic Syndrome. An Immunomodulatory Perspective to Alleviate the Storm Creator An entity primarily responsible for making the resource Roberto Giacomelli, Yehuda Shoenfeld, Paola Cipriani, Piero Ruscitti, Paola Di Benedetto, Onorina Berardicurti, Anna Maria Iagnocco Description An account of the resource The coronavirus disease 2019 (COVID-19), an acute respiratory disease caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has been declared as a worldwide public health emergency. Interestingly, severe COVID-19 is characterized by fever, hyperferritinemia, and a hyper-inflammatory process with a massive release of pro-inflammatory cytokines, which may be responsible for the high rate of mortality. These findings may advocate for a similarity between severe COVID-19 and some challenging rheumatic diseases, such as adult onset Still's disease, secondary hemophagocytic lymphohistiocytosis, and catastrophic anti-phospholipid syndrome, which have been included in the “hyperferritinemic syndrome” category. Furthermore, as performed in these hyper-inflammatory states, severe COVID-19 may benefit from immunomodulatory therapies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Hyperferritinemia, adult-onset Still's disease, Haemophagocytic lymphohistiocytosis, Hyper-inflammation, COVID-19, hyperferritinaemic syndrome Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fimmu.2020.01130 Source A related resource from which the described resource is derived Frontiers in Immunology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy