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            <name>Title</name>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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              <text>Respiratory DNA viruses are undetectable in nasopharyngeal secretions from adenotonsillectomized children.</text>
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              <text>Ronaldo Bragança Martins, Lucas Penna Rocha, Mirela Moreira Prates, Talita Bianca Gagliardi, Balduino Biasoli, Marcelo Junqueira Leite, Guilherme Buzatto, Miguel Ângelo Hyppolito, Davi Casale Aragon, Edwin Tamashiro, Fabiana Cardoso Pereira Valera, Eurico Arruda, Wilma Terezinha Anselmo-Lima</text>
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              <text>Respiratory viruses are frequently detected in association with chronic tonsillar hypertrophy in the absence of symptoms of acute respiratory infection (ARI). The present analysis was done in follow-up to a previous clinical study done by this same group. Nasopharyngeal washes (NPWs) were obtained from 83 of 120 individuals at variable times post adenotonsillectomy, in the absence of ARI symptoms. A look back at virus detection results in NPWs from the same 83 individuals at the time of tonsillectomy revealed that 73.5% (61/83) were positive for one or more viruses. The overall frequency of respiratory virus detection in post-tonsillectomy NPWs was 58.8%. Rhinovirus (RV) was the agent most frequently detected, in 38 of 83 subjects (45.8%), followed by enterovirus in 7 (8.4%), human metapneumovirus in 6 (7.2%), human respiratory syncytial virus in 3 (3.6%) and human coronavirus in 1 (1.2%). Remarkably, there was no detection of adenovirus (HAdV) or human bocavirus (HBoV) in asymptomatic individuals in follow-up of adenotonsillectomy. In keeping with persistence of respiratory DNA viruses in human tonsils, tonsillectomy significantly reduces asymptomatic shedding of HAdV and HBoV in NPWs.</text>
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              <text>2017</text>
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              <text>DOI: 10.1371/journal.pone.0174188</text>
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              <text>PLoS ONE</text>
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          <name>Publisher</name>
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              <text>Public Library of Science (PLoS)</text>
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          <name>Coverage</name>
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              <text>Science, Medicine</text>
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          <name>Language</name>
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              <text>EN</text>
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