https://socictopen.socict.org/files/original/514bbadf01a9a014e910062bcb5b2102.pdf b8c09324790c88af64e77196decf7420 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Use of Core Warming as a Treatment for Coronavirus Disease 2019 (COVID-19): an Initial Mathematical Model Creator An entity primarily responsible for making the resource Erik Kulstad, Roger Bedimo, Victor Kostov, Konstantin Kostov, Marcela Mercado-Montoya, Nathaniel Bonfanti, Emily Gundert, Anne Meredith Drewry, Shailee Shah Description An account of the resource Introduction: Increasing data suggest that elevated body temperature may be helpful in resolving a variety of diseases, including sepsis, acute respiratory distress syndrome (ARDS), and viral illnesses such as SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19). A mechanical provision of elevated temperature focused in a body region of high viral activity in patients undergoing mechanical ventilation may offer a therapeutic option that avoids arrhythmias seen with some pharmaceutical treatments. This study investigated the potential to actively provide core warming to the lungs of patients with a commercially available heat transfer device via mathematical modeling, and examined the influence of blood perfusion on temperature using this approach. Methods: Using the software Comsol Multiphysics, the authors modeled and simulated heat transfer in the body from an intraesophageal warming device, taking into account the airflow from patient ventilation. The simulation was focused on heat transfer and warming of the lungs and performed on a simplified geometry of an adult human body and airway from the pharynx to the lungs. Results: Simulations were run over a range of values for blood perfusion rate, since the heat capacity and density remain relatively constant. The highest temperature in this case is the device warming water temperature, and that heat diffuses by conduction to the nearby tissues, including the air flowing in the airways. At the range of blood perfusion investigated, maximum lung temperature ranged from 37.6 to 38.6°C. Conclusions: The provision of core warming may offer an innovative approach to treating infectious diseases from viral illnesses such as COVID-19, while avoiding the arrhythmogenic complications of currently used pharmaceutical treatments. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource body temperature, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: https://doi.org/10.24207/jca.v33i1.3382 Source A related resource from which the described resource is derived Journal of Cardiac Arrhythmias Publisher An entity responsible for making the resource available Linceu Editorial Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the circulatory (Cardiovascular) system