https://socictopen.socict.org/files/original/bb9e3d1e38858f88e5eadea68050c1dd.pdf 1e04392634aeed2b68829b685bba80be Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Pentoxifylline: An Immunomodulatory Drug for the Treatment of COVID-19 Creator An entity primarily responsible for making the resource R.B. Subramanian, Vasudev R. Thakkar, Hiren A. Dhameliya, Gauravi N. Trivedi, Sureshkumar N. Mesara Description An account of the resource Rapidly spreading outbreak of the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)is causing serious health concerns worldwide. It started as an epidemic in Wuhan, Hubei province,central China, and has now become a pandemic, spreading over most of the continents of the planet. Themajor clinical symptoms of the infection are dry cough, fever, pneumonia, respiratory failure, hypoxia,and in certain cases, even death. Alveolar damage and respiratory system failure are observed in severecases. Initial mild infection leads to activation of the immune system in the lungs and accumulationof various inflammatory cells and molecules. At a later phase during the infection, a “cytokine storm”causes an Acute Respiratory Distress Syndrome (ARDS), leading to an increase in the production ofpro-inflammatory cytokines, migration of a large number of immune cells to the site of infection, andultimately pulmonary damage. The rapid and uncontrolled outbreak requires putative therapeuticdrugs for treatment of patients suffering from COVID-19. Amongst the currently used antiviral drugs,such as hydroxychloroquine, lopinavir, remdesivir etc. we would like to present an update on anothereffective drug, pentoxifylline. Pentoxifylline has anti-inflammatory, immunomodulatory, anti-viral,and bronchodilatory properties. Pentoxifylline is known to reduce cytokine production, immune cellmigration, and suppress certain signal transduction pathways (e.g. NF-κβ and STAT3). Thus, it minimizesinflammatory damage in the lung tissues. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource cytokines, anti-inflammatory, antiviral, Pentoxifylline, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.22207/JPAM.14.SPL1.23 Source A related resource from which the described resource is derived Journal of Pure and Applied Microbiology Publisher An entity responsible for making the resource available Journal of Pure and Applied Microbiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology