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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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              <text>Sequence homology between HLA-bound cytomegalovirus and human peptides: A potential trigger for alloreactivity.</text>
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              <text>Charles E. Hall, Vishal N Koparde, Maximilian Jameson-Lee, Abdelrhman G Elnasseh, Allison F Scalora, David J Kobulnicky, Myrna G Serrano, Catherine H Roberts, Gregory A. Buck, Michael C Neale, Daniel E Nixon, Amir A Toor</text>
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              <text>Human cytomegalovirus (hCMV) reactivation may often coincide with the development of graft-versus-host-disease (GVHD) in stem cell transplantation (SCT). Seventy seven SCT donor-recipient pairs (DRP) (HLA matched unrelated donor (MUD), n = 50; matched related donor (MRD), n = 27) underwent whole exome sequencing to identify single nucleotide polymorphisms (SNPs) generating alloreactive peptide libraries for each DRP (9-mer peptide-HLA complexes); Human CMV CROSS (Cross-Reactive Open Source Sequence) database was compiled from NCBI; HLA class I binding affinity for each DRPs HLA was calculated by NetMHCpan 2.8 and hCMV- derived 9-mers algorithmically compared to the alloreactive peptide-HLA complex libraries. Short consecutive (≥6) amino acid (AA) sequence homology matching hCMV to recipient peptides was considered for HLA-bound-peptide (IC50</text>
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              <text>2017</text>
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              <text>DOI: 10.1371/journal.pone.0178763</text>
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              <text>PLoS ONE</text>
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              <text>Public Library of Science (PLoS)</text>
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              <text>Science, Medicine</text>
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              <text>EN</text>
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