Arginine and Endothelial Function

Arginine and Endothelial Function

Jessica Gambardella, Wafiq Khondkar, Marco Bruno Morelli, Xujun Wang, Gaetano Santulli, Valentina Trimarco

Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide production. In this systematic review, we focus on the functional role of arginine in the regulation of endothelial function and vascular tone. Both clinical and preclinical studies are examined, analyzing the effects of arginine supplementation in hypertension, ischemic heart disease, aging, peripheral artery disease, and diabetes mellitus.

2020

covid-19, Blood pressure, arginine, BH4, ADMA, arginine paradox

10.3390/biomedicines8080277

Epidemiology and Health

Korean Society of Epidemiology

Biology (General)