Hydroxychloroquine-induced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus

Hydroxychloroquine-induced hyperpigmentation in a 14-year-old female with systemic lupus erythematosus

Alexander KC Leung, Tara McMillan, Andrea Human, Joseph M Lam

Hydroxychloroquine (HCQ)-induced hyperpigmentation is uncommon but is increasingly recognized. To our knowledge, HCQ-induced hyperpigmentation has not been reported in the pediatric age group. Herein, we present the case of a 14-year-old girl with systemic lupus erythematosus, who developed hyperpigmentation on her shins and dorsum of the left foot, approximately 3 years after initiating treatment with HCQ. Physicians who treat children with HCQ for reasons such as rheumatologic disorders, dermatologic disorders and, more recently, coronavirus disease-19 should be aware of this less-known side effect of HCQ.

2020

covid-19, chloroquine, melanin, Rheumatologic disorders, dermatologic disorders

10.7573/dic.2020-5-8

Drugs in Context

BioExcel Publishing Ltd

Therapeutics. Pharmacology