<i>N</i>-(2-(1<i>H</i>-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

<i>N</i>-(2-(1<i>H</i>-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide

Stanimir Manolov, Iliyan Ivanov, Dimitar Bojilov

N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro-[1,1′-biphenyl]-4-yl)propanamide was prepared by a reaction between tryptamine and flurbiprofen, applying N,N’-dicyclohexylcarbodiimide, as a coupling agent. The obtained new amide has a fragment similar to Brequinar, a compound used in SARS-CoV-2 treatment trials. The newly synthesized compound was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

2021

SARS-CoV-2, amide, tryptamine, Flurbiprofen

10.3390/M1177

Epidemiology and Health

Korean Society of Epidemiology

Inorganic chemistry