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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>Detecting Human-to-Human Transmission of Avian Influenza A (H5N1)</text>
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          <name>Creator</name>
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              <text>Yang Yang, M. Elizabeth Halloran, Jonathan D. Sugimoto, Ira M. Longini</text>
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              <text>Highly pathogenic avian influenza A (HPAI) subtype H5N1 has caused family case clusters, mostly in Southeast Asia, that could be due to human-to-human transmission. Should this virus, or another zoonotic influenza virus, gain the ability of sustained human-to-human transmission, an influenza pandemic could result. We used statistical methods to test whether observed clusters of HPAI (H5N1) illnesses in families in northern Sumatra, Indonesia, and eastern Turkey were due to human-to-human transmission. Given that human-to-human transmission occurs, we estimate the infection secondary attack rates (SARs) and the local basic reproductive number, R0. We find statistical evidence of human-to-human transmission (p = 0.009) in Sumatra but not in Turkey (p = 0.114). For Sumatra, the estimated household SAR was 29% (95% confidence interval [CI] 15%–51%). The estimated lower limit on the local R0 was 1.14 (95% CI 0.61–2.14). Effective HPAI (H5N1) surveillance, containment response, and field evaluation are essential to monitor and contain potential pandemic strains.</text>
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          <name>Date</name>
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              <text>2007</text>
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          <name>Subject</name>
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              <text>human influenza, Outbreaks, Surveillance, control, Data analysis, mathematical model</text>
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          <name>Identifier</name>
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              <text>DOI: 10.3201/eid1309.070111</text>
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              <text>Emerging Infectious Diseases</text>
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          <name>Publisher</name>
          <description>An entity responsible for making the resource available</description>
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              <text>Centers for Disease Control and Prevention</text>
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          <name>Coverage</name>
          <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <text>Infectious and parasitic diseases, Medicine</text>
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          <name>Language</name>
          <description>A language of the resource</description>
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              <text>EN</text>
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