Interferon-β 1a and SARS Coronavirus Replication
SARS, interferon, coronavirus, treatment, therapy
A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon (IFN)-β 1a potently inhibits SARS coronavirus replication in vitro.
Lisa E. Hensley, Elizabeth A. Fritz, Peter B. Jahrling, Christopher Karp, John W. Huggins, Thomas W. Geisbert
Centers for Disease Control and Prevention
Infectious and parasitic diseases, Medicine