Interferon-β 1a and SARS Coronavirus Replication
subject: SARS, interferon, coronavirus, treatment, therapy
description: A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon (IFN)-β 1a potently inhibits SARS coronavirus replication in vitro.
creator: Lisa E. Hensley, Elizabeth A. Fritz, Peter B. Jahrling, Christopher Karp, John W. Huggins, Thomas W. Geisbert
source: Emerging Infectious Diseases
publisher: Centers for Disease Control and Prevention
date: 2004
language: EN
identifier: DOI: 10.3201/eid1002.030482
coverage: Infectious and parasitic diseases, Medicine