COVID-19: Mechanisms of Vaccination and Immunity

COVID-19: Mechanisms of Vaccination and Immunity

Daniel E. Speiser, Martin F. Bachmann

Vaccines are needed to protect from SARS-CoV-2, the virus causing COVID-19. Vaccines that induce large quantities of high affinity virus-neutralizing antibodies may optimally prevent infection and avoid unfavorable effects. Vaccination trials require precise clinical management, complemented with detailed evaluation of safety and immune responses. Here, we review the pros and cons of available vaccine platforms and options to accelerate vaccine development towards the safe immunization of the world’s population against SARS-CoV-2. Favorable vaccines, used in well-designed vaccination strategies, may be critical for limiting harm and promoting trust and a long-term return to normal public life and economy.

2020

serology, immunity, covid-19, SARS-CoV-2, Vaccination, nucleic acid tests

10.3390/vaccines8030404

Epidemiology and Health

Korean Society of Epidemiology

Medicine