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                <text>Coronavirus</text>
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                <text>Dominio científico: Coronavirus</text>
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          <name>Title</name>
          <description>A name given to the resource</description>
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              <text>The United States Drug Enforcement Administration and Prescription Opioid Production Quotas: An End Game of Eradication?</text>
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          <name>Creator</name>
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              <text>Schatman ME, Wegrzyn EL</text>
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              <text>Michael E Schatman,1,2 Erica L Wegrzyn3 1Department of Diagnostic Sciences, Tufts University School of Dental Medicine, Boston, MA, USA; 2Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, Ma, USA; 3Department of Pharmacy, Stratton VA Medical Center, Albany, NY, USACorrespondence: Michael E Schatman Tel +1 425 647-4880Email Michael.Schatman@tufts.edu As a means of mitigating the now concluded prescription opioid crisis in the United&amp;nbsp;States, the Drug Enforcement Administration (DEA) has, in its infinite wisdom,&amp;nbsp;embarked on a campaign of annually reducing the Aggregate Production Quota&amp;nbsp;(APQ) of opioids each year since 2017. According to the DEA, they began reducing&amp;nbsp;the APQ because there was no longer the need for a 25% &amp;ldquo;buffer&amp;rdquo; of excess opioids&amp;nbsp;due to decreases in prescribing each year.1 In 2017, production of almost every&amp;nbsp;opioid manufactured in the United States was reduced by at least 25%.1 In 2018,&amp;nbsp;APQs of opioids &amp;ndash; including oxycodone, hydrocodone, oxymorphone, hydromorphone,&amp;nbsp;morphine, codeine, meperidine, and fentanyl &amp;ndash; were reduced by 20%&amp;nbsp;compared to 2017 production.2 For 2019, DEA reduced APQs only of &amp;ldquo;more&amp;nbsp;commonly prescribed schedule II opioids, including oxycodone, hydrocodone,&amp;nbsp;oxymorphone, hydromorphone, morphine, and fentanyl&amp;rdquo;.3 The 2020 production&amp;nbsp;decreases affected 5 commonly-used opioids: Oxycodone production was decreased&amp;nbsp;by 9%, hydrocodone by 19%, hydromorphone by 25%, fentanyl by 31%, and&amp;nbsp;oxymorphone by 55%.4 Given, in response to the need for increased availability&amp;nbsp;of opioids associated with the COVID-19 crisis, DEA made small adjustments&amp;nbsp;(increases of 10&amp;ndash;15%) in production APQs in April of 2020 of analgesics including&amp;nbsp;codeine, fentanyl, hydromorphone, and morphine.5 Unfortunately, this action was&amp;nbsp;too little, too late. Hospitals that had already been sounding the alarm for the past&amp;nbsp;several years regarding routine shortages of parenteral opioids suddenly were faced&amp;nbsp;with inadequate supplies essential for treating patients on ventilators amidst&amp;nbsp;COVID-19, with the need for IV formulations increasing more than twofold.6 &amp;nbsp;</text>
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              <text>2020</text>
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              <text>not required for an editorial</text>
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          <name>Source</name>
          <description>A related resource from which the described resource is derived</description>
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              <text>Biotemas</text>
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              <text>Universidade Federal de Santa Catarina</text>
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              <text>Medicine (General)</text>
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